Microstructured Optical Fiber Based Distributed Sensor for In Vivo Pressure Detection

Microstructured optical fiber based distributed pressure sensor is proposed and demonstrated for high resolution manometry (HRM), which adopts the hybrid wavelength and frequency division multiplexing architecture, and hyperelastic packaging. The microstructure acting as a sensing element is composed of two identical and closely spaced ultrashort fiber Bragg gratings with the reflectivity of only 1%. In theory, 243 microstructures can be multiplexed along one single fiber with an interval of 10 mm beneficial from the compact structure, hybrid encoding feature, and low insertion loss. Homogeneous elastic packaging is explored to protect the fiber and greatly enhance the lateral pressure sensitivity of the sensor. Moreover, a mechanical model is established through the finite element method to analyze the sensitizing effect of the packaging. A prototype system is built and experimentally demonstrated the distributed pressure measurement with the spatial resolution of 10 mm and the pressure sensitivity up to 2.2 Nm/mPa. Due to the advantage of high spatial resolution, high multiplexing capacity, and high pressure sensitivity, the proposed sensor is suitable for HRM in medical application.

[1]  L. Reekie,et al.  Optical in-fibre grating high pressure sensor , 1993 .

[2]  M. Fox,et al.  High‐resolution manometry predicts the success of oesophageal bolus transport and identifies clinically important abnormalities not detected by conventional manometry , 2004, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[3]  Jan Mehner,et al.  Characterization of fiber Bragg grating-based sensor array for high resolution manometry , 2012, Photonics Europe.

[4]  J. Pandolfino,et al.  Incidence and Prevalence of Achalasia in Central Chicago, 2004–2014, Since the Widespread Use of High‐Resolution Manometry , 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[5]  L. Duan,et al.  A comparative study of 22-channel water-perfusion system and solid-state system with 36-sensors in esophageal manometery , 2012, BMC Gastroenterology.

[6]  T. Erdogan Fiber grating spectra , 1997 .

[7]  Ming Zhang,et al.  Three-dimensional finite element analysis of the foot during standing--a material sensitivity study. , 2005, Journal of biomechanics.

[8]  C. R. Dennison,et al.  A Distributed Pressure Measurement System Comprising Multiplexed In-Fibre Bragg Gratings Within a Flexible Superstructure , 2012, Journal of Lightwave Technology.

[9]  J. Brasseur,et al.  Space-time pressure structure of pharyngo-esophageal segment during swallowing. , 2001, American journal of physiology. Gastrointestinal and liver physiology.

[10]  A. Bredenoord,et al.  Oesophageal high-resolution manometry: moving from research into clinical practice , 2007, Gut.

[11]  P. Wild,et al.  Demonstration of a flexible, highly sensitive catheter for high resolution manometry based on in-fibre Bragg gratings , 2012, Other Conferences.

[12]  Serguei V. Miridonov,et al.  Twin-grating fiber optic sensor demodulation , 2001 .

[13]  Deming Liu,et al.  M-OTDR sensing system based on 3D encoded microstructures , 2017, Scientific reports.

[14]  Jan Tack,et al.  The migrating motor complex: control mechanisms and its role in health and disease , 2012, Nature Reviews Gastroenterology &Hepatology.

[15]  Subhas Banerjee,et al.  Esophageal function testing. , 2012, Gastrointestinal endoscopy.

[16]  P. Dinning,et al.  In-vivo demonstration of a high resolution optical fiber manometry catheter for diagnosis of gastrointestinal motility disorders. , 2009, Optics express.

[17]  K. Srimannarayana,et al.  Polymer Packaged Fiber Grating Pressure Sensor with Enhanced Sensitivity , 2014 .

[18]  H. Sheng,et al.  A lateral pressure sensor using a fiber Bragg grating , 2004, IEEE Photonics Technology Letters.

[19]  Deming Liu,et al.  Simultaneous wavelength and frequency encoded microstructure based quasi-distributed temperature sensor. , 2012, Optics express.

[20]  Jan Mehner,et al.  Homogeneous catheter for esophagus high-resolution manometry using fiber Bragg gratings , 2010, BiOS.

[21]  Anbo Wang,et al.  Multiplexed Fiber Fabry–Pérot Interferometer Sensors Based on Ultrashort Bragg Gratings , 2007, IEEE Photonics Technology Letters.

[22]  Elfed Lewis,et al.  Optical Fibre Pressure Sensors in Medical Applications , 2015, Sensors.

[23]  Seyed Mojtaba Zebarjad,et al.  A study on the tensile properties of silicone rubber/polypropylene fibers/silica hybrid nanocomposites. , 2016, Journal of the mechanical behavior of biomedical materials.

[24]  S. Roman,et al.  Normative values in esophageal high‐resolution manometry , 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[25]  P. Dinning,et al.  Design of a high-sensor count fibre optic manometry catheter for in-vivo colonic diagnostics. , 2009, Optics express.

[26]  J.W. Arkwright,et al.  The use of wavelength division multiplexed fiber Bragg grating sensors for distributed sensing of pressure in the gastrointestinal tract , 2008, 2008 IEEE PhotonicsGlobal@Singapore.

[27]  P. Dinning,et al.  A fibre optic catheter for simultaneous measurement of longitudinal and circumferential muscular activity in the gastrointestinal tract , 2011, Journal of biophotonics.

[28]  S. Tjin,et al.  Fiber Bragg grating based shear-force sensor: modeling and testing , 2004, Journal of Lightwave Technology.