Ehrlich-reacting protein in kidneys of tumor-bearing rats.

Summary A basic protein has been isolated from the kidneys of Jensen sarcoma-bearing Sprague-Dawley rats which is not present in the kidneys of normal animals of the same strain. The purification and isolation of this protein can be analytically followed because it gives a strong colored reaction with Ehrlich reagent. The protein, obtained in crystalline form, has been shown to behave as a single component electrophoretically and in the ultracentrifuge. A significant positive correlation has been shown to exist between the amount of this protein present in the kidney extracts and the weight of the tumor.