Intracranial Microwave Hyperthermia: Heat Induction and Temperature Control

Malignant brain tumors cannot be effectively managed with conventional therapeutic modalities. The unique anatomical characteristics of the brain, the ease of lesion localization, and the dismal prognosis for this disease offer a viable (although quite formidable) proving ground for the development and tcsting of hyperthermal therapy. This paper deals with three of the four basic problems underlying the administration of intracranial hyperthermia¿heat induction, temperature measurement, and temperature control. The fourth, and as yet unsolved, problem of predicting spatial temperature distributions is discussed.

[1]  Samaras Gm,et al.  Microwave hyperthermia for cancer therapy. , 1981 .

[2]  L. Taylor,et al.  Implantable radiators for cancer therapy by microwave hyperthermia , 1980, Proceedings of the IEEE.

[3]  R. Britt,et al.  Feasibility of ultrasound hyperthermia in the treatment of malignant brain tumors. , 1983, Medical instrumentation.

[4]  T. W. Athey,et al.  Dielectric properties of animal tissues in vivo at frequencies 10 MHz--1 GHz. , 1981, Bioelectromagnetics.

[5]  D. Morton,et al.  Localized magnetic‐loop induction hyperthermia of the rabbit brain , 1982, Journal of surgical oncology.

[6]  M. Salcman,et al.  Hyperthermia for brain tumors: biophysical rationale. , 1981, Neurosurgery.

[7]  G M Samaras,et al.  Direct contact applicators for microwave hyperthermia. , 1981, The Journal of microwave power.

[8]  R. C. Eggleton,et al.  ULTRASOUND POTENTIATION OF CHEMOTHERAPY FOR BRAIN MALIGNANCY , 1975 .

[9]  J. Strohbehn,et al.  A Method for Measurement of the Permittivity of Thin Samples , 1979 .

[10]  Hyperthermia for Brain Tumors , 1981 .

[11]  B. Stuart Trembly,et al.  Blood Flow Effects on the Temperature Distributions from an Invasive Microwave Antenna Array Used in Cancer Therapy , 1982, IEEE Transactions on Biomedical Engineering.

[12]  J W Strohbehn,et al.  An invasive microwave antenna for locally-induced hyperthermia for cancer therapy. , 1979, The Journal of microwave power.

[13]  A. W. Guy,et al.  Analyses of Electromagnetic Fields Induced in Biological Tissues by Thermographic Studies on Equivalent Phantom Models , 1971 .

[14]  J. Strohbehn,et al.  Localized Hyperthermia in the Treatment of Malignant Brain Tumors Using an Interstitial Microwave Antenna Array , 1984, IEEE Transactions on Biomedical Engineering.