Sex drives Tregs into fat
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Androgens promote inflammation in visceral adipose tissue (VAT), leading to the expansion of a distinct IL-33 producing stromal population and recruitment of Tregs. Androgens promote inflammation in visceral adipose tissue (VAT), leading to the expansion of a distinct IL-33 producing stromal population and recruitment of Tregs.
[1] David Chisanga,et al. Sex-specific adipose tissue imprinting of regulatory T cells , 2020, Nature.