Protein Structure and Engineering
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[1] C. Walsh,et al. Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide. , 1982, The Journal of biological chemistry.
[2] L. Kay,et al. Three-Dimensional Heteronuclear NMR of 15 N-Labeled Proteins , 2022 .
[3] Richard Earl Dickerson,et al. Hemoglobin : structure, function, evolution, and pathology , 1983 .
[4] J. LEE,et al. Nuclear Magnetic Resonance , 1968, Nature.
[5] D. Powers,et al. In vivo formation and stability of engineered disulfide bonds in subtilisin. , 1986, The Journal of biological chemistry.
[6] W. Bialek,et al. Do vibrational spectroscopies uniquely describe protein dynamics? The case for myoglobin. , 1985, Biophysical journal.
[7] Ronald M. Levy,et al. Molecular dynamics of an a-helical polypeptide: Temperature dependence and deviation from harmonic behavior (protein dynamics/temperature factor/quantum corrections/fluctuations/normal modes) , 1982 .
[8] A. Cooper. Dynamics of Proteins and Nucleic Acids , 1988 .
[9] I. Solomon. Relaxation Processes in a System of Two Spins , 1955 .
[10] I. R. Mcdonald,et al. Theory of simple liquids , 1998 .
[11] E. M.,et al. Statistical Mechanics , 2021, Manual for Theoretical Chemistry.
[12] W. M. Westler,et al. Two-dimensional NMR approaches to the study of protein structure and function. , 1984, Federation proceedings.
[13] K. Moffat,et al. The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins. , 1986, The Journal of biological chemistry.
[14] K. Wüthrich,et al. Carbon‐13 NMR chemical shifts of the common amino acid residues measured in aqueous solutions of the linear tetrapeptides H‐Gly‐Gly‐ X‐L‐ Ala‐OH , 1978 .
[15] T. Grundström,et al. Expression of bovine intestinal calcium binding protein from a synthetic gene in Escherichia coli and characterization of the product. , 1986, Biochemistry.
[16] Terrence G. Oas,et al. A peptide model of a protein folding intermediate , 1988, Nature.
[17] P. Karplus,et al. Refined structure of glutathione reductase at 1.54 A resolution. , 1987, Journal of molecular biology.
[18] E. Haas,et al. Estimation of intramolecular distance distributions in bovine pancreatic trypsin inhibitor by site-specific labeling and nonradiative excitation energy-transfer measurements. , 1987, Biochemistry.
[19] M. Uziel,et al. REACTION OF BOVINE PANCREATIC RIBONUCLEASE A WITH 1,5-DIFLUORO-2,4-DINITROBENZENE. II. STRUCTURE OF AN INTRAMOLECULARLY BRIDGED DERIVATIVE. , 1965, The Journal of biological chemistry.
[20] J. Markley. High-resolution proton magnetic resonance spectroscopy of selectively deuterated enzymes. , 1972, Methods in enzymology.
[21] Structure and dynamics of detergent-solubilized M13 coat protein (an integral membrane protein) determined by 13C and 15N nuclear magnetic resonance spectroscopy. , 1990, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[22] I. Yamazaki,et al. Diffusion effect on excitation energy transfer in solution: Analysis by means of picosecond time-resolved fluorimeter , 1985 .
[23] N. Scrutton,et al. Engineering of an intersubunit disulphide bridge in glutathione reductase from Escherichia coli , 1988, FEBS letters.
[24] W C Johnson,et al. Information content in the circular dichroism of proteins. , 1981, Biochemistry.
[25] J. H. Noggle. The nuclear Overhauser effect , 1971 .
[26] S. Opella,et al. Detection of 1H homonuclear NOE between amide sites in proteins with 1H15N heteronuclear correlation spectroscopy , 1989 .
[27] R. Kaptein,et al. Nonselective three-dimensional nmr spectroscopy. The 3D NOE-HOHAHA experiment , 1988 .
[28] A. Bacher,et al. Riboflavin synthases of Bacillus subtilis. Purification and properties. , 1980, The Journal of biological chemistry.
[29] S. Fesik,et al. Amide proton exchange rates of a bound pepsin inhibitor determined by isotope-edited proton NMR experiments. , 1987, Biochemical and biophysical research communications.
[30] A. Bax,et al. Optimization of two-dimensional homonuclear relayed coherence transfer NMR spectroscopy , 1985 .
[31] M. Laskowski,et al. Soybean trypsin inhibitor (Kunitz) and its complex with trypsin. Carbon-13 nuclear magnetic resonance studies of the reactive site arginine. , 1980, Biochemistry.
[32] D. Parry,et al. α-Helical coiled coils — a widespread motif in proteins , 1986 .
[33] Benno P. Schoenborn,et al. Neutron diffraction reveals oxygen–histidine hydrogen bond in oxymyoglobin , 1981, Nature.
[34] C. Dobson,et al. Sequential 1H NMR assignments and secondary structure of hen egg white lysozyme in solution. , 1988, Biochemistry.
[35] L. J. Perry,et al. Disulfide bonds and thermal stability in T4 lysozyme. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[36] P G Schultz,et al. A general method for site-specific incorporation of unnatural amino acids into proteins. , 1989, Science.
[37] H. Lipson. Crystal Structures , 1949, Nature.
[38] R. Griffey,et al. Proton NMR measurements of bacteriophage T4 lysozyme aided by 15N isotopic labeling: structural and dynamic studies of larger proteins. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[39] A. Gronenborn,et al. Multinuclear NMR characterization of two coexisting conformational states of the Lactobacillus casei dihydrofolate reductase-trimethoprim-NADP+ complex. , 1984, Biochemistry.
[40] Michael Levitt,et al. Refinement of Large Structures by Simultaneous Minimization of Energy and R Factor , 1978 .
[41] P. Karplus,et al. A crystallographic study of the glutathione binding site of glutathione reductase at 0.3-nm resolution. , 1989, European journal of biochemistry.
[42] R. Schirmer,et al. Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain. , 1982, European journal of biochemistry.
[43] Kurt Wüthrich,et al. Stereospecific assignment of the methyl 1H NMR lines of valine and leucine in polypeptides by nonrandom 13C labelling , 1989 .
[44] P. Model,et al. Sequence of thioredoxin reductase from Escherichia coli. Relationship to other flavoprotein disulfide oxidoreductases. , 1988, The Journal of biological chemistry.
[45] S. Walter Englander,et al. Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR , 1988, Nature.
[46] L. Bonewald,et al. A naturally occurring structural variant of human growth hormone. , 1978, The Journal of biological chemistry.
[47] A. Szabó,et al. Model-free approach to the interpretation of nuclear magnetic resonance relaxation in macromolecules. 1. Theory and range of validity , 1982 .
[48] L. Verlet. Computer "Experiments" on Classical Fluids. I. Thermodynamical Properties of Lennard-Jones Molecules , 1967 .
[49] R. Woody. Aromatic side‐chain contributions to the far ultraviolet circular dichroism of peptides and proteins , 1978 .
[50] A. Jones,et al. Biosynthetic 20-kilodalton methionyl-human growth hormone has diabetogenic and insulin-like activities. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[51] M Karplus,et al. Hemoglobin tertiary structural change on ligand binding. Its role in the co-operative mechanism. , 1983, Journal of molecular biology.
[52] W. D. Phillips,et al. Manifestations of the tertiary structures of proteins in high-frequency nuclear magnetic resonance. , 1967, Journal of the American Chemical Society.
[53] J M Burridge,et al. Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim. , 1985, The Journal of biological chemistry.
[54] R. Griffey,et al. Proton-detected heteronuclear edited and correlated nuclear magnetic resonance and nuclear Overhauser effect in solution , 1987, Quarterly Reviews of Biophysics.
[55] R. Perham,et al. The lipoamide dehydrogenase component of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli. , 1978, Biochemical Society transactions.
[56] J. Kirkwood,et al. The Radial Distribution Function in Liquids , 1942 .
[57] V. Bystrov. Spin—spin coupling and the conformational states of peptide systems , 1976 .
[58] M. Karplus,et al. Crystallographic R Factor Refinement by Molecular Dynamics , 1987, Science.
[59] H. Rüterjans,et al. Nuclear magnetic resonance investigation of 15N-labeled histidine in aqueous solution. , 1977, Journal of the American Chemical Society.
[60] F. Winkler,et al. Crystal structure of human dihydrofolate reductase complexed with folate. , 1988, European journal of biochemistry.
[61] P. Wright,et al. Complete assignment of the 1H nuclear magnetic resonance spectrum of French bean plastocyanin. Application of an integrated approach to spin system identification in proteins. , 1988, Journal of molecular biology.
[62] J T Yang,et al. Calculation of protein conformation from circular dichroism. , 1986, Methods in enzymology.
[63] P. Wright,et al. Assignment of heme and distal amino acid resonances in the 1H-NMR spectra of the carbon monoxide and oxygen complexes of sperm whale myoglobin. , 1985, Biochimica et biophysica acta.
[64] J. Anglister,et al. NMR technique for assessing contributions of heavy and light chains to an antibody combining site , 1985, Nature.
[65] M Karplus,et al. X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution. , 1986, Journal of molecular biology.
[66] E. Southern. Detection of specific sequences among DNA fragments separated by gel electrophoresis. , 1975, Journal of molecular biology.
[67] M. Kainosho,et al. Local structural features around the C-terminal segment of Streptomyces subtilisin inhibitor studied by carbonyl carbon nuclear magnetic resonances three phenylalanyl residues. , 1987, Biochemistry.
[68] L. Retegui,et al. The intriguing nature of the multiple actions of growth hormone , 1979 .
[69] A. J. Shaka,et al. An improved sequence for broadband decoupling: WALTZ-16 , 1983 .
[70] P. Wright,et al. Site-selective observation of nuclear Overhauser effects in proteins via isotopic labeling , 1987 .
[71] M Karplus,et al. Estimation of uncertainties in X‐ray refinement results by use of perturbed structures , 1987, Proteins.
[72] A. Gronenborn,et al. Determination of the secondary structure of the DNA binding protein Ner from phage Mu using 1H homonuclear and 15N-1H heteronuclear NMR spectroscopy. , 1989, Biochemistry.
[73] B. Sykes,et al. Backbone dynamics of a model membrane protein: measurement of individual amide hydrogen-exchange rates in detergent-solubilized M13 coat protein using 13C NMR hydrogen/deuterium isotope shifts. , 1987, Biochemistry.
[74] Thomas A. Weber,et al. Hidden structure in liquids , 1982 .
[75] R. L. Baldwin,et al. Detection of an early intermediate in the folding of ribonuclease A by protection of amide protons against exchange. , 1979, Journal of molecular biology.
[76] C. Ho,et al. 19F NMR Investigations of Membranes , 1985 .
[77] J. Feeney,et al. Trimethoprim binding to Lactobacillus casei dihydrofolate reductase: a 13C NMR study using selectively 13C-enriched trimethoprim. , 1986, Biochemistry.
[78] E. Purcell,et al. Effects of Diffusion on Free Precession in Nuclear Magnetic Resonance Experiments , 1954 .
[79] D. G. Davis,et al. OBSERVATION OF 1000-FOLD ENHANCEMENT OF NITROGEN-15 NMR VIA PROTON-DETECTED MULTIQUANTUM COHERENCES: STUDIES OF LARGE PEPTIDES , 1985 .
[80] L. Bonewald,et al. Altered proteolytic cleavage of human growth hormone as a result of deamidation. , 1981, The Journal of biological chemistry.
[81] Rudolf Rigler,et al. Polarized fluorescence and rotational brownian motion , 1972 .
[82] M Karplus,et al. Active site dynamics of ribonuclease. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[83] T. A. Jones,et al. A graphics model building and refinement system for macromolecules , 1978 .
[84] R. Griffey,et al. Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR☆ , 1983 .
[85] K. Wuethrich,et al. The development of nuclear magnetic resonance spectroscopy as a technique for protein structure determination , 1989 .
[86] H. Susi,et al. Resolution-enhanced Fourier transform infrared spectroscopy of enzymes. , 1986, Methods in enzymology.
[87] B C Finzel,et al. Three-dimensional structure of an antibody-antigen complex. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[88] Ronald M. Levy,et al. NMR relaxation parameters in molecules with internal motion: exact Langevin trajectory results compared with simplified relaxation models , 1981 .
[89] C. Hansch,et al. Crystal structure of avian dihydrofolate reductase containing phenyltriazine and NADPH. , 1982, The Journal of biological chemistry.
[90] R. B. Moon,et al. Applications of natural-abundance nitrogen-15 nuclear magnetic resonance to large biochemically important molecules. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[91] M. Ehrenberg,et al. Fluorescence relaxation spectroscopy in the analysis of macromolecular structure and motion , 1976, Quarterly Reviews of Biophysics.
[92] M Karplus,et al. Picosecond dynamics of tyrosine side chains in proteins. , 1979, Biochemistry.
[93] J. Hopfield,et al. CO binding to heme proteins: A model for barrier height distributions and slow conformational changes , 1983 .
[94] J. Anglister,et al. Distances of tyrosine residues from a spin-label hapten in the combining site of a specific monoclonal antibody. , 1984, Biochemistry.
[95] Kevin M. Smith,et al. Proton nuclear magnetic resonance investigation of the conformation-dependent spin equilibrium in azide-ligated monomeric insect hemoglobins , 1983 .
[96] C M Dobson,et al. Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig alpha-lactalbumin. , 1989, Biochemistry.
[97] E. Bradbury,et al. Thermal denaturation studies of acetylated nucleosomes and oligonucleosomes. , 1982, European journal of biochemistry.
[98] J. Feeney,et al. Dihydrofolate reductase. 1H resonance assignments and coenzyme-induced conformational changes. , 1986, Journal of molecular biology.
[99] G. Fasman. Circular dichroism analysis of chromatin and DNA--nuclear protein complexes. , 1978, Methods in cell biology.
[100] R. Ladenstein,et al. Electrostatic effects in a large enzyme complex: Subunit interactions and electrostatic potential field of the icosahedral β60 capsid of heavy riboflavin synthase , 1989, Proteins.
[101] P. Artymiuk,et al. X-ray studies of water in crystals of lysozyme. , 1983, Journal of molecular biology.
[102] J. Blanchard,et al. Glutathione reductase: solvent equilibrium and kinetic isotope effects. , 1988, Biochemistry.
[103] J. Hoch,et al. A structural study of the hydrophobic box region of lysozyme in solution using nuclear Overhauser effects. , 1980, Biochemistry.
[104] Axel T. Brunger,et al. A memory-efficient fast Fourier transformation algorithm for crystallographic refinement on supercomputers , 1989 .
[105] W. Horrocks,et al. Evaluation of dipolar nuclear magnetic resonance shifts in low-spin hemin systems: ferricytochrome c and metmyoglobin cyanide. , 1973, Biochimica et biophysica acta.
[106] A. Bax,et al. Measurement of carbon-13 longitudinal relaxation using 1H detection , 1987 .
[107] J. Kirkwood,et al. THE NUCLEAR MAGNETIC RESONANCE SPECTRUM OF RIBONUCLEASE1 , 1957 .
[108] M. Krahl,et al. Diabetogenic peptide from human growth hormone: partial purification from peptic digest and long-term action in ob/ob mice. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[109] R. Rigler,et al. Picosecond Time Domain Spectroscopy of Structure and Dynamics in Nucleic Acids , 1986 .
[110] A. M. Skene,et al. TRIAL OF TISSUE PLASMINOGEN ACTIVATOR FOR MORTALITY REDUCTION IN ACUTE MYOCARDIAL INFARCTION Anglo-Scandinavian Study of Early Thrombolysis (ASSET) , 1988, The Lancet.
[111] J. B. Johnson,et al. Rebinding and relaxation in the myoglobin pocket. , 1987, Biophysical chemistry.
[112] S. Fesik,et al. Isotope-edited proton NMR study on the structure of a pepsin/inhibitor complex. , 1988, Biochemistry.
[113] J. Bandekar,et al. Vibrational spectroscopy and conformation of peptides, polypeptides, and proteins. , 1986, Advances in protein chemistry.
[114] J. Andrew McCammon,et al. The dynamic picture of protein structure , 1983 .
[115] K Wüthrich,et al. A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules. , 1980, Biochemical and biophysical research communications.
[116] F. Stillinger,et al. Packing Structures and Transitions in Liquids and Solids , 1984, Science.
[117] M. Karplus,et al. Active site dynamics in protein molecules: A stochastic boundary molecular‐dynamics approach , 1985, Biopolymers.
[118] M Karplus,et al. Time dependence of atomic fluctuations in proteins: analysis of local and collective motions in bovine pancreatic trypsin inhibitor. , 1982, Biochemistry.
[119] G. Reeke,et al. Three-dimensional structure of beta 2-microglobulin. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[120] Wayne A. Hendrickson,et al. Structure of the hydrophobic protein crambin determined directly from the anomalous scattering of sulphur , 1981, Nature.
[121] M. Llinás,et al. Analysis of the aromatic 1H-NMR spectrum of the kringle 5 domain from human plasminogen. Evidence for a conserved kringle fold. , 1988, European journal of biochemistry.
[122] Lou Reinisch,et al. Protein fluctuations, distributed coupling, and the binding of ligands to heme proteins , 1988 .
[123] R. R. Ernst,et al. Improvement of pulse performance in N.M.R. coherence transfer experiments , 1983 .
[124] K. Wüthrich,et al. 15N-labeled P22 c2 repressor for nuclear magnetic resonance studies of protein-DNA interactions , 1987, European Biophysics Journal.
[125] K. Wüthrich. NMR of proteins and nucleic acids , 1988 .
[126] M. Karplus,et al. Fluorescence depolarization of tryptophan residues in proteins: a molecular dynamics study. , 1983, Biochemistry.
[127] W. Caughey,et al. Infrared spectroscopy of a single cell--the human erythrocyte. , 1988, Biochemical and biophysical research communications.
[128] M. Karplus,et al. Restraints in temperature-factor refinement for macromolecules: an evaluation by molecuar dynamics , 1985 .
[129] H. Mantsch,et al. New insight into protein secondary structure from resolution-enhanced infrared spectra. , 1988, Biochimica et biophysica acta.
[130] R. Poljak,et al. Three-dimensional structure of immunoglobulins. , 1979, Annual review of biochemistry.
[131] L. Yu,et al. Directly observed 15N NMR spectra of uniformly enriched proteins. , 1987, Biochemistry.
[132] Richard R. Ernst,et al. Investigation of exchange processes by two‐dimensional NMR spectroscopy , 1979 .
[133] J. Richardson,et al. The anatomy and taxonomy of protein structure. , 1981, Advances in protein chemistry.
[134] A M Gronenborn,et al. Determination of three-dimensional structures of proteins and nucleic acids in solution by nuclear magnetic resonance spectroscopy. , 1989, Critical reviews in biochemistry and molecular biology.
[135] M. Karplus,et al. Harmonic dynamics of proteins: normal modes and fluctuations in bovine pancreatic trypsin inhibitor. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[136] A. Gronenborn,et al. Long‐range 15N‐1H correlation as an aid to sequential proton resonance assignment of proteins Application to the DNA‐binding protein ner from phage Mu , 1988, FEBS letters.
[137] J. Feeney,et al. 15N and 1H NMR evidence for multiple conformations of the complex of dihydrofolate reductase with its substrate, folate , 1987, FEBS letters.
[138] C. Dobson,et al. Proton nuclear Overhauser effects and protein dynamics , 1981 .
[139] NMR OF PROTONS COUPLED TO CARBON-13 NUCLEI ONLY , 1981 .
[140] M. Karplus,et al. Hidden thermodynamics of mutant proteins: a molecular dynamics analysis. , 1989, Science.
[141] R. Zinkernagel,et al. Identical Vβ T-cell receptor genes used in alloreactive cytotoxic and antigen plus I–A specific helper T cells , 1985, Nature.
[142] L. C. Allen,et al. Strong, positive‐ion hydrogen bonds: The binary complexes formed from NH3, OH2, FH, PH3, SH2, and ClH , 1980 .
[143] G. Schulz,et al. The catalytic mechanism of glutathione reductase as derived from x-ray diffraction analyses of reaction intermediates. , 1983, The Journal of biological chemistry.
[144] B. Oh,et al. Carbon-13-spin-system-directed strategy for assigning cross peaks in the COSY fingerprint region of a protein , 1989 .
[145] G. Bricogne,et al. Methods and programs for direct‐space exploitation of geometric redundancies , 1976 .
[146] M. Karplus,et al. Crystallographic refinement by simulated annealing: application to crambin , 1989 .
[147] D. Wiley,et al. Crystallization and X-ray diffraction studies on the histocompatibility antigens HLA-A2 and HLA-A28 from human cell membranes. , 1985, Journal of molecular biology.
[148] G. L. Kenyon,et al. Studies of macromolecular structure by 13 C nuclear magnetic resonance. II. A specific labeling approach to the study of histidine residues in proteins. , 1973, Journal of the American Chemical Society.
[149] J. Bolin,et al. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate. , 1982, The Journal of biological chemistry.
[150] C. Janeway,et al. Molecular characterization of antibodies bearing Id-460. II. Molecular basis for Id-460 expression , 1985, The Journal of experimental medicine.
[151] F. Richards,et al. Anion binding and pH-dependent electrostatic effects in ribonuclease. , 1982, Biochemistry.
[152] W. Caughey,et al. Determination of anesthetic molecule environments by infrared spectroscopy. I. Effects of solvating molecule structure on nitrous oxide spectra. , 1985, Archives of biochemistry and biophysics.
[153] D. Doddrell,et al. Conformation and segmental motion of native and denatured ribonuclease A in solution. Application of natural-abundance carbon-13 partially relaxed Fourier transform nuclear magnetic resonance. , 1971, Journal of the American Chemical Society.
[154] K. Wüthrich. Protein structure determination in solution by nuclear magnetic resonance spectroscopy. , 1989, Science.
[155] G. Lomakka,et al. Picosecond Single Photon Fluorescence Spectroscopy of Nucleic Acids , 1984, Topical Meeting on Ultrafast Phenomena.
[156] K. Rothschild,et al. Fourier transform infrared techniques for probing membrane protein structure. , 1988, Annual review of biophysics and biophysical chemistry.
[157] Wolfgang Doster,et al. Dynamical transition of myoglobin revealed by inelastic neutron scattering , 1989, Nature.
[158] J. H. Brown. A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules , 1988, Nature.
[159] T. Grundström,et al. The role of protein surface charges in ion binding , 1988, Nature.
[160] C. Walsh,et al. Mercuric reductase: homology to glutathione reductase and lipoamide dehydrogenase. Iodoacetamide alkylation and sequence of the active site peptide. , 1983, Biochemistry.
[161] D. Leahy,et al. Sequences of 12 monoclonal anti-dinitrophenyl spin-label antibodies for NMR studies. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[162] C. Nicolini. Biophysics and cancer , 1986 .
[163] E. Lattman,et al. Representation of phase probability distributions for simplified combination of independent phase information , 1970 .
[164] A. Böck,et al. Genes for stable RNA in the extreme thermophile Thermoproteus tenax: introns and transcription signals , 1987, The EMBO journal.
[165] L. Nilsson,et al. Structural fluctuations of a helical polypeptide traversing a lipid bilayer. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[166] P. Wright,et al. Assignment of resonances in the 1H nuclear magnetic resonance spectrum of the carbon monoxide complex of sperm whale myoglobin by phase-sensitive two-dimensional techniques. , 1987, Journal of molecular biology.
[167] M. Levitt,et al. Protein normal-mode dynamics: trypsin inhibitor, crambin, ribonuclease and lysozyme. , 1985, Journal of molecular biology.
[168] J. Kirkwood. Statistical Mechanics of Fluid Mixtures , 1935 .
[169] J. Strominger,et al. Human class II major histocompatibility complex genes and proteins. , 1988, Annual review of biochemistry.
[170] K. Wüthrich,et al. Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. , 1983, Biochemical and biophysical research communications.
[171] S. Harrison. Multiple modes of subunit association in the structures of simple spherical viruses , 1984 .
[172] K Wüthrich,et al. Sequential resonance assignments as a basis for determination of spatial protein structures by high resolution proton nuclear magnetic resonance. , 1982, Journal of molecular biology.
[173] Wayne A. Hendrickson,et al. A restrained-parameter thermal-factor refinement procedure , 1980 .
[174] A. Bax,et al. Simplification of two-dimensional NOE spectra of proteins by 13C labeling , 1987 .
[175] B. Roth,et al. Recent progress in the medicinal chemistry of 2,4-diaminopyrimidines. , 1982, Progress in medicinal chemistry.
[176] Hans Frauenfelder,et al. Temperature-dependent X-ray diffraction as a probe of protein structural dynamics , 1979, Nature.
[177] M. Karplus,et al. Electronic structure of cyanide complexes of hemes and heme proteins. , 1971, Journal of molecular biology.
[178] W. Baumeister,et al. Decoration and shadowing of freeze-etched catalase crystals. , 1985, Ultramicroscopy.
[179] A. Drake,et al. An analysis of the 225–230‐nm CD band of elapid toxins , 1988, Biopolymers.
[180] W. Zinth,et al. Femtosecond Spectroscopy of the Primary Events of Bacterial Photosynthesis , 1986 .
[181] Måns Ehrenberg,et al. Rotational brownian motion and fluorescence intensify fluctuations , 1974 .
[182] M Karplus,et al. Conformations of intermediates in the folding of the pancreatic trypsin inhibitor. , 1987, Journal of molecular biology.
[183] R. Dwek,et al. NMR in Biological Research: Peptides and Proteins , 1978 .
[184] J. Anglister,et al. Nonaromatic amino acids in the combining site region of a monoclonal anti-spin-label antibody. , 1984, Biochemistry.
[185] L. Gráf,et al. Human pituitary growth hormone: isolation and properties of two biologically active fragments from plasmin digests. , 1974, Proceedings of the National Academy of Sciences of the United States of America.
[186] M. Levitt,et al. Automatic identification of secondary structure in globular proteins. , 1977, Journal of molecular biology.
[187] H Frauenfelder,et al. Control and pH dependence of ligand binding to heme proteins. , 1982, Biochemistry.
[188] P. Bolton. Heteronuclear relay transfer spectroscopy with proton detection , 1985 .
[189] P. A. Peterson,et al. Chemical, physical-chemical, and immunological properties of papain-solubilized human transplatation antigens. , 1979, Biochemistry.
[190] F. Stillinger,et al. Improved simulation of liquid water by molecular dynamics , 1974 .
[191] A. Bax,et al. 1H and13C Assignments from Sensitivity-Enhanced Detection of Heteronuclear Multiple-Bond Connectivity by 2D Multiple Quantum NMR , 1986 .
[192] B. Oh,et al. Protein carbon-13 spin systems by a single two-dimensional nuclear magnetic resonance experiment. , 1988, Science.
[193] E. Ulrich,et al. NMR relaxation study of internal motions in Staphylococcal nuclease , 1988 .
[194] M. Karplus,et al. CHARMM: A program for macromolecular energy, minimization, and dynamics calculations , 1983 .
[195] S. Fesik,et al. Heteronuclear three-dimensional nmr spectroscopy. A strategy for the simplification of homonuclear two-dimensional NMR spectra , 1988 .
[196] K. Wüthrich,et al. Carbon-13 nuclear magnetic resonance studies of the selectively isotope-labeled reactive site peptide bond of the basic pancreatic trypsin inhibitor in the complexes with trypsin, trypsinogen, and anhydrotrypsin. , 1980, Biochemistry.
[197] H. Berendsen,et al. ALGORITHMS FOR MACROMOLECULAR DYNAMICS AND CONSTRAINT DYNAMICS , 1977 .
[198] G. Wagner,et al. Measurement of 13C spin-spin relaxation times by two-dimensional heteronuclear 1H13C correlation spectroscopy , 1989 .
[199] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[200] S. Provencher,et al. Estimation of globular protein secondary structure from circular dichroism. , 1981, Biochemistry.
[201] Claudio Nicolini,et al. Pepto: An expert system for automatic peak assignment of two‐dimensional nuclear magnetic resonance spectra of proteins , 1990 .
[202] K Wüthrich,et al. Sequential resonance assignments in protein 1H nuclear magnetic resonance spectra. Computation of sterically allowed proton-proton distances and statistical analysis of proton-proton distances in single crystal protein conformations. , 1982, Journal of molecular biology.
[203] G. Clore,et al. Nuclear magnetic resonance study of the globular domain of chicken histone H5: resonance assignment and secondary structure. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[204] Ad Bax,et al. Line narrowing of amide proton resonances in 2D NMR spectra of proteins , 1989 .
[205] L. J. Lewis,et al. The 20,000-dalton variant of human growth hormone: location of the amino acid deletions. , 1980, Biochemical and biophysical research communications.
[206] P. Parham,et al. Carbohydrate moiety of HLA antigens. Antigenic properties and amino acid sequences around the site of glycosylation. , 1977, The Journal of biological chemistry.
[207] E. Knapp,et al. Protein dynamics. Mössbauer spectroscopy on deoxymyoglobin crystals. , 1982, Journal of molecular biology.
[208] F. Bovey,et al. Polymer NSR spectroscopy. I. The motion and configuration of polymer chains in solution , 1959 .
[209] M. Karplus,et al. Structure and internal mobility of proteins: A molecular dynamics study of hen egg white lysozyme , 1986, Biopolymers.
[210] G A Petsko,et al. Fluctuations in protein structure from X-ray diffraction. , 1984, Annual review of biophysics and bioengineering.
[211] H. Grey,et al. Autologous peptides constitutively occupy the antigen binding site on Ia. , 1988, Science.
[212] H. Crespi,et al. Proton Magnetic Resonance of Proteins Fully Deuterated except for 1H-Leucine Side Chains , 1968, Science.
[213] L. A. Day,et al. Circular dichroism and ultraviolet absorption of a deoxyribonucleic acid binding protein of filamentous bacteriophage. , 1973, Biochemistry.
[215] D. Lancet,et al. Heavy chain of HLA-A and HLA-B antigens is conformationally labile: a possible role for beta 2-microglobulin. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[216] George M. Church,et al. A structure-factor least-squares refinement procedure for macromolecular structures using constrained and restrained parameters , 1977 .
[217] D. Cowburn,et al. Assignment of 15N NMR signals in bovine pancreatic trypsin inhibitor , 1987 .
[218] J. Strominger,et al. Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line. , 1987, The Journal of biological chemistry.
[219] A. Bax,et al. Long range heteronuclear correlation. A powerful tool for the NMR analysis of medium-size proteins , 1988 .
[220] G. McFeters,et al. Induction and Characterization of β-Galactosidase in an Extreme Thermophile , 1972, Journal of bacteriology.
[221] A. Bacher. Heavy riboflavin synthase from Bacillus subtilis. , 1986, Methods in enzymology.
[222] P. Seeburg,et al. Efficient bacterial expression of bovine and porcine growth hormones. , 1983, DNA.
[223] Robert L. Baldwin,et al. NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A , 1988, Nature.
[224] D. Thouless,et al. Models of Disorder: The Theoretical Physics of Homogeneously Disordered Systems , 1979 .
[225] R. Kretsinger,et al. Structure and evolution of calcium-modulated proteins. , 1980, CRC critical reviews in biochemistry.
[226] R. Boelens,et al. Three-dimensional J-resolved NMR spectroscopy , 1987 .
[227] A. Bax,et al. NMR signal assignments of amide protons in the alpha-helical domains of staphylococcal nuclease. , 1988, Biochemistry.
[228] J. Markley,et al. Two-dimensional nuclear magnetic resonance spectroscopy of proteins: an overview. , 1989, Methods in enzymology.
[229] S. Hyberts,et al. Stereospecific assignments of side-chain protons and characterization of torsion angles in Eglin c. , 1987, European journal of biochemistry.
[230] G. K. Ackers,et al. Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[231] E. Kabat,et al. Sequences of proteins of immunological interest , 1991 .
[232] W. Zillig,et al. Transcription termination in the archaebacterium Sulfolobus: signal structures and linkage to transcription initiation. , 1988, Nucleic acids research.
[233] M. Levitt,et al. Contribution of tryptophan residues to the combining site of a monoclonal anti dinitrophenyl spin-label antibody. , 1987, Biochemistry.
[234] L. Kay,et al. Sensitivity enhancement of 13C T1 measurements via polarization transfer , 1987 .
[235] M. J. Chatfield,et al. Solvent isotope effects on NMR spectral parameters in high-spin ferric hemoproteins: an indirect probe for distal hydrogen bonding. , 1988, Biochimica et biophysica acta.
[236] J. M. Kwiatkoski,et al. FT-IR microspectrometry advances , 1987, Nature.
[237] G. Careri,et al. Soliton-assisted unidirectional circulation in a biochemical cycle. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[238] W. F. van Gunsteren,et al. Effect of constraints on the dynamics of macromolecules , 1982 .
[239] S. Forsén,et al. Chapter 4 – Biophysical Studies of Calmodulin , 1986 .
[240] James E. Roberts,et al. Two-dimensional heteronuclear chemical shift correlation spectroscopy in rotating solids , 1984 .
[241] M. Druger,et al. EVOLUTIONARY DIVERGENCE BETWEEN TWO POPULATIONS OF DROSOPHILA PSEUDOOBSCURA , 1977, Evolution; international journal of organic evolution.
[242] D. G. Davis,et al. Paramagnetic proton nuclear magnetic resonance shifts of metmyoglobin, methemoglobin, and hemin derivatives. , 1968, Journal of the American Chemical Society.
[243] J. Anglister,et al. Magnetic resonance of a monoclonal anti-spin-label antibody , 1984 .
[244] J. Markley,et al. Methods of Stable-Isotope-Assisted Protein NMR Spectroscopy in Solution , 1989 .
[245] M. Kainosho,et al. Assignment of the three methionyl carbonyl carbon resonances in Streptomyces subtilisin inhibitor by a carbon-13 and nitrogen-15 double-labeling technique. A new strategy for structural studies of proteins in solution. , 1982, Biochemistry.
[246] M Karplus,et al. Dynamics of proteins: elements and function. , 1983, Annual review of biochemistry.
[247] R. Perham,et al. An amino acid sequence in the active site of lipoamide dehydrogenase from pig heart. , 1974, Biochemical Journal.
[248] Ronald M. Levy,et al. Vibrational approach to the dynamics of an α‐helix , 1979 .
[249] A. Bacher,et al. Biosynthesis of riboflavin in Bacillus subtilis: function and genetic control of the riboflavin synthase complex , 1978, Journal of bacteriology.
[250] M. Karplus,et al. Internal motion of proteins: nuclear magnetic resonance measurements and dynamic simulations. , 1986, Methods in enzymology.
[251] B. Sykes,et al. Backbone dynamics of a model membrane protein: 13C NMR spectroscopy of alanine methyl groups in detergent-solubilized M13 coat protein. , 1986, Biochemistry.
[252] R. Levy,et al. Interactions of antibody aromatic residues with a peptide of cholera toxin observed by two-dimensional transferred nuclear Overhauser effect difference spectroscopy. , 1989, Biochemistry.
[253] H. Bunn,et al. Hemoglobin: Molecular, Genetic and Clinical Aspects , 1984 .
[254] Jen-Tsi Yang,et al. Two-Point Calibration of Circular Dichrometer with d-10-Camphorsulfonic Acid , 1977 .
[255] S. Ogawa,et al. Assignments of the paramagnetically shifted heme methyl nuclear magnetic resonance peaks of cyanometmyoglobin by selective deuteration. , 1974, Journal of molecular biology.
[256] Kurt Wüthrich,et al. Experimental techniques of two-dimensional correlated spectroscopy , 1980 .
[257] N. Brown,et al. Nucleotide sequence of a gene from the Pseudomonas transposon Tn501 encoding mercuric reductase. , 1983, Biochemistry.
[258] M. Summers. 113Cd NMR spectroscopy of coordination compounds and proteins , 1988 .
[259] P. Marrack,et al. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. , 1986, Advances in immunology.
[260] S. Phillips,et al. Structure and refinement of oxymyoglobin at 1.6 A resolution. , 1980, Journal of molecular biology.
[261] J. Markley,et al. Staphylococcal nuclease active-site amino acids: pH dependence of tyrosines and arginines by 13C NMR and correlation with kinetic studies. , 1989, Biochemistry.
[262] P. Lu,et al. Lambda cro repressor complex with OR3 DNA: 15N NMR observations. , 1987, Biochemistry.
[263] H. Senn,et al. Protein structure and interactions by combined use of sequential NMR assignments and isotope labeling , 1987 .
[264] L. Kay,et al. Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1 beta. , 1989, Biochemistry.
[265] R D Young,et al. Protein states and proteinquakes. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[266] G. Montelione,et al. 2D chemical exchange NMR spectroscopy by proton-detected heteronuclear correlation , 1989 .
[267] M. A. Saper,et al. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens , 1987, Nature.
[268] Side chain mobility in bovine calbindin D9k. Rotational motion of Tyr13. , 1990, European journal of biochemistry.
[269] G. Bodenhausen,et al. Principles of nuclear magnetic resonance in one and two dimensions , 1987 .
[270] M. Perutz,et al. Molecular Pathology of Human Haemoglobin: Stereochemical Interpretation of Abnormal Oxygen Affinities , 1971, Nature.
[271] A. Fairlamb,et al. Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases. , 1986, Biochemistry.
[272] M. Brunori,et al. Enzyme Proteins. (Book Reviews: Hemoglobin and Myoglobin in Their Reactions with Ligands) , 1971 .
[273] F. Richards,et al. NMR sequential assignment of Escherichia coli thioredoxin utilizing random fractional deuteriation. , 1988, Biochemistry.
[274] S. Forsén,et al. 43Ca NMR studies of calcium binding to proteins: Interpretation of experimental data by bandshape analysis , 1983 .
[275] J. Feeney,et al. The charge state of trimethoprim bound to Lactobacillus casei dihydrofolate reductase , 1981, FEBS letters.
[276] A. Lesk,et al. How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins. , 1980, Journal of molecular biology.
[277] Barry Robson,et al. Introduction to proteins and protein engineering , 1986 .
[278] I. Kuntz,et al. Diffusion‐collision model for the folding kinetics of myoglobin , 1988, Proteins.
[279] H Frauenfelder,et al. Dynamics of ligand binding to myoglobin. , 1975, Biochemistry.
[280] D. Isenman,et al. The structure and function of immunoglobulin domains: studies with beta-2-microglobulin on the role of the intrachain disulfide bond. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[281] J. Satterlee,et al. Axial histidyl imidazole non-exchangeable proton resonances as indicators of imidazole hydrogen bonding in ferric cyanide complexes of heme peroxidases. , 1982, Biochimica et biophysica acta.
[282] S. Fesik,et al. Heteronuclear three-dimensional NMR spectroscopy of the inflammatory protein C5a. , 1989, Biochemistry.
[283] D. G. Davis,et al. Natural-abundance 15N NMR studies of Turkey ovomucoid third domain. Assignment of peptide 15N resonances to the residues at the reactive site region via proton-detected multiple-quantum coherence , 1986 .
[284] J. Markley,et al. Assignment of the histidine proton magnetic resonance peaks of soybean trypsin inhibitor (Kunitz) by a differertial deuterium exchange technique. , 1975, Biochemistry.
[285] A. Fairlamb,et al. Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme. , 1987, European Journal of Biochemistry.
[286] F. A. Cotton,et al. Staphylococcal nuclease: proposed mechanism of action based on structure of enzyme-thymidine 3',5'-bisphosphate-calcium ion complex at 1.5-A resolution. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[287] C. Chothia,et al. Hydrophobic bonding and accessible surface area in proteins , 1974, Nature.
[288] W. M. Westler,et al. Two-dimensional NMR strategies for carbon-carbon correlations and sequence-specific assignments in carbon-13 labeled proteins , 1988 .
[289] J. Feeney,et al. Dynamics of trimethoprim bound to dihydrofolate reductase. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[290] A. Malcolm. Amino acid sequence homology. , 1979, Journal of theoretical biology.
[291] Champion,et al. Spectral broadening in biomolecules. , 1986, Physical review letters.
[292] L. Franco,et al. Structural studies on histones H1. Circular dichroism and difference spectroscopy of the histones H1 and their trypsin-resistant cores from calf thymus and from the fruit fly Ceratitis capitata. , 1980, Biochemistry.
[293] J. Feeney,et al. Direct 19F NMR observation of the conformational selection of optically active rotamers of the antifolate compound fluoronitropyrimethamine bound to the enzyme dihydrofolate reductase , 1988, FEBS letters.
[294] M. Bokranz,et al. Nucleotide sequence of the methyl coenzyme M reductase gene cluster from Methanosarcina barkeri. , 1987, Nucleic acids research.
[295] L. J. Perry,et al. Unpaired cysteine-54 interferes with the ability of an engineered disulfide to stabilize T4 lysozyme. , 1986, Biochemistry.
[296] R. R. Ernst,et al. Novel three-dimensional NMR techniques for studies of peptides and biological macromolecules , 1987 .
[297] K. Wüthrich,et al. Amide protein exchange and surface conformation of the basic pancreatic trypsin inhibitor in solution. Studies with two-dimensional nuclear magnetic resonance. , 1982, Journal of molecular biology.
[298] P. Chambon,et al. The segmented paper method: DNA synthesis and mutagenesis by rapid microscale "shotgun gene synthesis". , 1987, Methods in enzymology.
[299] P. Kraulis,et al. Three-dimensional NMR spectroscopy of a protein in solution , 1988, Nature.
[300] B. E. Kimmel,et al. Trypanothione reductase of Trypanosoma congolense: gene isolation, primary sequence determination, and comparison to glutathione reductase. , 1988, Biochemistry.
[301] N. Green,et al. Optical rotatory dispersion, circular dichroism and far-ultraviolet spectra of avidin and streptavidin. , 1966, The Biochemical journal.
[302] S. Radford,et al. 2-Oxo acid dehydrogenase multi-enzyme complexes: in the beginning and halfway there. , 1987, Biochemical Society symposium.
[303] M Karplus,et al. The internal dynamics of globular proteins. , 1981, CRC critical reviews in biochemistry.
[304] G. Wagner,et al. Selective excitation of 1H resonances coupled to 13C. Hetero COSY and RELAY experiments with 1H detection for a protein , 1986 .
[305] S. Opella,et al. Protein backbone dynamics by solid-state and solution 15N NMR spectroscopy , 1987 .
[306] R. Perham,et al. Glutathione reductase from Escherichia coli: cloning and sequence analysis of the gene and relationship to other flavoprotein disulfide oxidoreductases. , 1986, Biochemistry.
[307] K. Wüthrich,et al. Editing of 2D 1H NMR spectra using X half-filters. combined use with residue-selective 15N labeling of proteins , 1986 .
[308] W. C. Johnson,et al. Secondary structure of proteins through circular dichroism spectroscopy. , 1988, Annual review of biophysics and biophysical chemistry.
[309] J. Markley. Correlation proton magnetic resonance studies at 250 MHz of bovine pancreatic ribonuclease. I. Reinvestigation of the histidine peak assignments. , 1975, Biochemistry.
[310] Y H Chen,et al. Determination of the helix and beta form of proteins in aqueous solution by circular dichroism. , 1974, Biochemistry.
[311] D. Bogenhagen,et al. Clusters of point mutations are found exclusively around rearranged antibody variable genes. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[312] L. Pauling,et al. The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain. , 1951, Proceedings of the National Academy of Sciences of the United States of America.
[313] N. Scrutton,et al. Switching kinetic mechanism and putative proton donor by directed mutagenesis of glutathione reductase. , 1989, Biochemistry.
[314] J Deisenhofer,et al. Crystallographic refinement and atomic models of the intact immunoglobulin molecule Kol and its antigen-binding fragment at 3.0 A and 1.0 A resolution. , 1980, Journal of molecular biology.
[315] G. Montelione,et al. Accurate measurements of homonuclear HN-H.alpha. coupling constants in polypeptides using heteronuclear 2D NMR experiments , 1989 .
[316] C. Nicolini. Chromatin structure: from nuclei to genes (review). , 1983, Anticancer research.
[317] M. Karplus,et al. Nuclear Magnetic Resonance Determination of the Angle Ψ in Peptides , 1972 .
[318] J. Tanner. Human Growth , 1876, Nature.
[319] H. Scheraga,et al. Structural Studies of Ribonuclease. XXIV. The Application of Nuclear Magnetic Resonance Spectroscopy to Distinguish between the Histidine Residues of Ribonuclease1 , 1966 .
[320] S. Baldwin,et al. Fourier transform infrared spectroscopic study of the structure and conformational changes of the human erythrocyte glucose transporter. , 1987, The Journal of biological chemistry.
[321] J. Katz,et al. Deuterated organisms: cultivation and uses. , 1966, Science.
[322] T. A. Osipova,et al. The effect of synthetic fragment 31-44 of human growth hormone on glucose uptake by isolated adipose tissue. , 1983, Biochemical and biophysical research communications.