Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues
暂无分享,去创建一个
[1] O. Delaneau,et al. Estimating the causal tissues for complex traits and diseases , 2016, Nature Genetics.
[2] Kyle J. Gaulton,et al. Genome-wide associations for birth weight and correlations with adult disease , 2016 .
[3] Jie Huang,et al. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps , 2016, Nature Genetics.
[4] Ayellet V. Segrè,et al. Colocalization of GWAS and eQTL Signals Detects Target Genes , 2016, bioRxiv.
[5] Olivier Delaneau,et al. A complete tool set for molecular QTL discovery and analysis , 2016, Nature Communications.
[6] Stephen C. J. Parker,et al. The genetic architecture of type 2 diabetes , 2016, Nature.
[7] Xiaoquan Wen,et al. Efficient Integrative Multi-SNP Association Analysis using Deterministic Approximation of Posteriors , 2015, bioRxiv.
[8] Benjamin A. Logsdon,et al. Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia , 2016, Nature Neuroscience.
[9] C. Spencer,et al. A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium , 2016, bioRxiv.
[10] Jakob Grove,et al. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population , 2015, Nature Genetics.
[11] Gabor T. Marth,et al. A global reference for human genetic variation , 2015, Nature.
[12] Matti Pirinen,et al. FINEMAP: efficient variable selection using summary data from genome-wide association studies , 2015, bioRxiv.
[13] Tom R. Gaunt,et al. The UK10K project identifies rare variants in health and disease , 2016 .
[14] Judy H. Cho,et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations , 2015, Nature Genetics.
[15] J. Danesh,et al. A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease , 2016 .
[16] Emmanouil T. Dermitzakis,et al. Fast and efficient QTL mapper for thousands of molecular phenotypes , 2015, bioRxiv.
[17] J. Barrett,et al. Strategies for fine-mapping complex traits , 2015, Human molecular genetics.
[18] Gregory A. Poland,et al. Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics , 2015, Genetics.
[19] Ross M. Fraser,et al. Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.
[20] Michael Q. Zhang,et al. Integrative analysis of 111 reference human epigenomes , 2015, Nature.
[21] Xiaoquan Wen,et al. Cross-Population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation , 2014, bioRxiv.
[22] Richard Durbin,et al. Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins , 2014, Nature Genetics.
[23] Gail Clement,et al. A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans , 2014, Nature Communications.
[24] Ross M. Fraser,et al. Defining the role of common variation in the genomic and biological architecture of adult human height , 2014, Nature Genetics.
[25] Eleazar Eskin,et al. Identifying Causal Variants at Loci with Multiple Signals of Association , 2014, Genetics.
[26] C. Spencer,et al. Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.
[27] Richard Durbin,et al. Genetic interactions affecting human gene expression identified by variance association mapping , 2014, eLife.
[28] Peggy Hall,et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations , 2013, Nucleic Acids Res..
[29] C. Wallace,et al. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics , 2013, PLoS genetics.
[30] Tanya M. Teslovich,et al. Discovery and refinement of loci associated with lipid levels , 2013, Nature Genetics.
[31] M. Pirinen,et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis , 2013, Nature Genetics.
[32] Pedro G. Ferreira,et al. Transcriptome and genome sequencing uncovers functional variation in humans , 2013, Nature.
[33] E. Prossnitz,et al. GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state. , 2013, Endocrinology.
[34] P. Arner,et al. NPC1 in human white adipose tissue and obesity , 2013, BMC Endocrine Disorders.
[35] M. Nogueira-Barbosa,et al. Increased vertebral morphometric fracture in patients with postsurgical hypoparathyroidism despite normal bone mineral density , 2013, BMC Endocrine Disorders.
[36] M. Stephens,et al. A Statistical Framework for Joint eQTL Analysis in Multiple Tissues , 2012, PLoS genetics.
[37] Roderic Guigó,et al. The GEM mapper: fast, accurate and versatile alignment by filtration , 2012, Nature Methods.
[38] Kenny Q. Ye,et al. An integrated map of genetic variation from 1,092 human genomes , 2012, Nature.
[39] Simon C. Potter,et al. Mapping cis- and trans-regulatory effects across multiple tissues in twins , 2012, Nature Genetics.
[40] Bronwen L. Aken,et al. GENCODE: The reference human genome annotation for The ENCODE Project , 2012, Genome research.
[41] J. Marchini,et al. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.
[42] Claude Bouchard,et al. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance , 2012, Nature Genetics.
[43] T. Trouard,et al. Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance. , 2011, Human molecular genetics.
[44] R. Erickson,et al. Decreased Npc1 Gene Dosage in Mice Is Associated With Weight Gain , 2010, Obesity.
[45] J. Marchini,et al. Genotype imputation for genome-wide association studies , 2010, Nature Reviews Genetics.
[46] E. Dermitzakis,et al. Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations , 2010, PLoS genetics.
[47] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[48] Richard Durbin,et al. Sequence analysis Fast and accurate short read alignment with Burrows – Wheeler transform , 2009 .
[49] Barbara Heude,et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations , 2009, Nature Genetics.
[50] M. Stephens,et al. Imputation-Based Analysis of Association Studies: Candidate Regions and Quantitative Traits , 2007, PLoS genetics.
[51] John D. Storey,et al. Statistical significance for genomewide studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[52] Elizabeth M. Smigielski,et al. dbSNP: the NCBI database of genetic variation , 2001, Nucleic Acids Res..
[53] International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome , 2001, Nature.
[54] Empirical nonparametric bootstrap strategies in quantitative trait loci mapping: conditioning on the genetic model. , 1998, Genetics.
[55] P M Visscher,et al. Confidence intervals in QTL mapping by bootstrapping. , 1996, Genetics.