Concomitant Cardiac Surgery and Pulmonary Resection

Abstract Background: Surgical management of concomitant pulmonary and cardiac disease remains controversial. There is no consensus on the use of a one-or two-staged procedure, the timing of heparinization and the utilisation of cardio-pulmonary bypass. Methods: We performed a retrospective review of 27 patients who underwent pulmonary and cardiac surgery, from 2000 to 2008, in two institutions. We focused on early postoperative morbidity and mortality. Results: 24 men and 3 women, with a mean age of 68 years, were treated. Cardiac procedures consisted of coronary artery bypass grafting (n = 22), heart valve surgery (n = 3) or a combination of both (n = 2). Pulmonary resection included segmental resection (n = 1), lobectomy (n = 21), bilobectomy (n = 2) and pneumonectomy (n = 3). Histology of the pulmonary lesion was squamous cell carcinoma in 14 patients (52%), adenocarcinoma in 10 (37%), large cell neuroendocrine tumour in 1 (3%) and typical carcinoid in 1 (3%). The stage of the pulmonary malignancy was IA in 8 patients (31%), stage IB in 11 (42%), stage IIB in 5 (19%) and stage IIIB in 2 (8%). A benign lesion was found in 1 patient (3%). There was no in-hospital mortality. Postoperative complications occurred in 16 patients (59%) consisting of supraventricular arrhythmias in 11 (41%), pneumonia in 8 (30%), atelectasis in 6 (22%), ventricular arrhythmias in 2 (7%), pneumothorax in 1 (3%), pleural effusion in 1 (3%), and renal insufficiency in 1 patient (3%). Revision for bleeding was necessary in 3 patients (11%). The mean follow-up was 30,7 months with a median survival for all patients of 46 months. Conclusions: Simultaneous procedures for cardiac disease and pulmonary lesions can be performed without life-threatening morbidity and no in-hospital mortality.

[1]  A. Carretta,et al.  Lung resection for cancer in patients with coronary arterial disease: analysis of short-term results. , 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  A. Elami,et al.  Lung cancer resection or aortic graft replacement with simultaneous myocardial revascularization without cardiopulmonary bypass. , 2001, Chest.

[3]  W. V. van Boven,et al.  Combined off-pump coronary surgery and right lung resections through midline sternotomy. , 2001, The Annals of thoracic surgery.

[4]  J. F. Keppel,et al.  Median sternotomy versus thoracotomy to resect primary lung cancer: analysis of 815 cases. , 2000, The Annals of thoracic surgery.

[5]  E. Moore,et al.  Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability. , 1999, The Journal of surgical research.

[6]  K. McManus,et al.  Simultaneous cardiac surgery with pulmonary resection: presentation of series and review of literature. , 1998, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[7]  W. van Oeveren,et al.  Reduction of the inflammatory response in patients undergoing minimally invasive coronary artery bypass grafting. , 1998, The Annals of thoracic surgery.

[8]  M. Komeda,et al.  Results of combined pulmonary resection and cardiac operation. , 1996, The Annals of thoracic surgery.

[9]  D. Melvin,et al.  Concomitant cardiac and pulmonary operation: the role of cardiopulmonary bypass. , 1992, The Annals of thoracic surgery.

[10]  Yohu Watanabe,et al.  Median Sternotomy as an Approach for Pulmonary Surgery , 1988, The Thoracic and cardiovascular surgeon.

[11]  H. Bülzebruck,et al.  Late Results of Surgical Treatment of Pulmonary Metastases , 1986, The Thoracic and cardiovascular surgeon.

[12]  H. Urschel,et al.  Median sternotomy as a standard approach for pulmonary resection. , 1986, The Annals of thoracic surgery.

[13]  J. Ernst,et al.  Concomitant open heart surgery and pulmonary resection for lung cancer. , 1995, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[14]  A. Terzi,et al.  Lung resections concomitant to coronary artery bypass grafting. , 1994, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[15]  R. Giudicelli,et al.  Is lung cancer surgery justified in patients with coronary artery disease? , 1994, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.