Myeloid dendritic cells from human cutaneous squamous cell carcinoma are poor stimulators of T-cell proliferation.

[1]  Lisa C. Zaba,et al.  Resident and "inflammatory" dendritic cells in human skin. , 2009, The Journal of investigative dermatology.

[2]  R. Steinman.  Linking innate to adaptive immunity through dendritic cells. , 2008, Novartis Foundation symposium.

[3]  J. Roliński,et al.  Dendritic cell subsets in the peritoneal fluid and peripheral blood of women suffering from ovarian cancer , 2008, Cytometry. Part B, Clinical cytometry.

[4]  Lisa C. Zaba,et al.  Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. , 2008, The Journal of investigative dermatology.

[5]  W. Peetermans,et al.  Aggressive Cutaneous Squamous Cell Carcinoma Associated with Prolonged Voriconazole Therapy in a Renal Transplant Patient , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[6]  P. De Baetselier,et al.  Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. , 2008, Blood.

[7]  L. Fouser,et al.  IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. , 2008, The Journal of clinical investigation.

[8]  H. Hurwitz,et al.  The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients , 2008, Cancer Immunology, Immunotherapy.

[9]  Lisa C. Zaba,et al.  Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses , 2007, The Journal of experimental medicine.

[10]  Jill P. Mesirov,et al.  GSEA-P: a desktop application for Gene Set Enrichment Analysis , 2007, Bioinform..

[11]  Erin G Harper,et al.  Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines , 2007, Current rheumatology reports.

[12]  J. Carucci,et al.  Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment. , 2007, The Journal of investigative dermatology.

[13]  R. Muschel,et al.  Distribution of dendritic cell subtypes in primary oral squamous cell carcinoma is inconsistent with a functional response. , 2007, Cancer letters.

[14]  J. Talmadge.  Pathways Mediating the Expansion and Immunosuppressive Activity of Myeloid-Derived Suppressor Cells and Their Relevance to Cancer Therapy , 2007, Clinical Cancer Research.

[15]  R. Steinman,et al.  Normal human dermis contains distinct populations of CD11c+BDCA-1+ dendritic cells and CD163+FXIIIA+ macrophages. , 2007, The Journal of clinical investigation.

[16]  Han-Sin Jeong,et al.  Vaccinations With Dendritic Cells Primed With Apoptotic Tumor Cells Can Elicit Preventive Antitumor Immunity in a Poorly Immunogenic Animal Model of Squamous Cell Carcinoma , 2007, The Laryngoscope.

[17]  J. Talmadge,et al.  Inflammatory cell infiltration of tumors: Jekyll or Hyde , 2007, Cancer and Metastasis Reviews.

[18]  A. Weinberg,et al.  Metastatic Cutaneous Squamous Cell Carcinoma: An Update , 2007, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[19]  T. Kopp,et al.  Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells , 2007, The Journal of experimental medicine.

[20]  James G Krueger,et al.  Novel Insight into the Agonistic Mechanism of Alefacept In Vivo: Differentially Expressed Genes May Serve as Biomarkers of Response in Psoriasis Patients1 , 2007, The Journal of Immunology.

[21]  M. Ladomery,et al.  Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm. , 2007, Cancer letters.

[22]  J. Carucci,et al.  Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis. , 2007, The Journal of allergy and clinical immunology.

[23]  H. Fujii,et al.  Vascular endothelial growth factor inhibits the function of human mature dendritic cells mediated by VEGF receptor-2 , 2007, Cancer Immunology, Immunotherapy.

[24]  G. Wood,et al.  Mohs Micrographic Surgery in the Treatment of Rare Aggressive Cutaneous Tumors: The Geisinger Experience , 2007, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[25]  B. Nickoloff.  Cracking the cytokine code in psoriasis , 2007, Nature Medicine.

[26]  Kathleen M. Smith,et al.  IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2–dependent mechanisms with implications for psoriasis pathogenesis , 2006, The Journal of experimental medicine.

[27]  H. Fujii,et al.  CD4(+)CD25high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers , 2006, Cancer Immunology, Immunotherapy.

[28]  Guoyou Chen,et al.  Induction of Allospecific Tolerance by Immature Dendritic Cells Genetically Modified to Express Soluble TNF Receptor1 , 2006, The Journal of Immunology.

[29]  H. Kuwano,et al.  Expression of Foxp3 in non-small cell lung cancer patients is significantly higher in tumor tissues than in normal tissues, especially in tumors smaller than 30 mm. , 2006, Oncology reports.

[30]  J. Ott,et al.  Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia. , 2006, The Journal of investigative dermatology.

[31]  R. Steinman,et al.  Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Signoretti,et al.  Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. , 2005, Cancer research.

[33]  D. Gabrilovich,et al.  STAT1 Signaling Regulates Tumor-Associated Macrophage-Mediated T Cell Deletion1 , 2005, The Journal of Immunology.

[34]  T. Giese,et al.  Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer. , 2003, Cancer research.

[35]  S. Endres,et al.  Interferon‐α disables dendritic cell precursors: dendritic cells derived from interferon‐α‐treated monocytes are defective in maturation and T‐cell stimulation , 2003 .

[36]  E. Pamer,et al.  TNF/iNOS-producing dendritic cells mediate innate immune defense against bacterial infection. , 2003, Immunity.

[37]  V. Bronte,et al.  L-arginine metabolism in myeloid cells controls T-lymphocyte functions. , 2003, Trends in immunology.

[38]  N. Bhardwaj,et al.  A clinical grade cocktail of cytokines and PGE2 results in uniform maturation of human monocyte-derived dendritic cells: implications for immunotherapy. , 2002, Vaccine.

[39]  C. Borrebaeck,et al.  Global reprogramming of dendritic cells in response to a concerted action of inflammatory mediators. , 2002, International immunology.

[40]  M. Dhodapkar,et al.  T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[41]  D. Gillatt,et al.  VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. , 2002, Cancer research.

[42]  M. Dhodapkar,et al.  The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells. , 2002, Blood.

[43]  O. Hrusak,et al.  Generation of functional dendritic cells for potential use in the treatment of acute lymphoblastic leukemia , 2002, Cancer Immunology, Immunotherapy.

[44]  T. Curiel,et al.  Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells , 2001, Nature Medicine.

[45]  Frank O. Nestle,et al.  Dendritic cells: On the move from bench to bedside , 2001, Nature Medicine.

[46]  David E. Misek,et al.  Profiling Changes in Gene Expression during Differentiation and Maturation of Monocyte-derived Dendritic Cells Using Both Oligonucleotide Microarrays and Proteomics* , 2001, The Journal of Biological Chemistry.

[47]  H. Young,et al.  Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes1 , 2000, The Journal of Immunology.

[48]  R. C. van der Veen,et al.  Macrophage-derived nitric oxide inhibits the proliferation of activated T helper cells and is induced during antigenic stimulation of resting T cells. , 2000, Cellular immunology.

[49]  N. Kadowaki,et al.  The nature of the principal type 1 interferon-producing cells in human blood. , 1999, Science.

[50]  M. Young,et al.  Myeloid progenitor cells mediate immune suppression in patients with head and neck cancers. , 1999, International journal of immunopharmacology.

[51]  A. Enk,et al.  Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells. , 1999, Blood.

[52]  G. Feng,et al.  Nitric oxide regulates Th1 cell development through the inhibition of IL‐12 synthesis by macrophages , 1998, European journal of immunology.

[53]  Dirk Schadendorf,et al.  Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells , 1998, Nature Medicine.

[54]  A. Enk,et al.  Dendritic cells as mediators of tumor‐induced tolerance in metastatic melanoma , 1997, International journal of cancer.

[55]  N. J. Eungdamrong,et al.  Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. , 2009, The Journal of investigative dermatology.

[56]  J. Kotarski,et al.  The role of dendritic cells in cytotoxic immune response regulation in ovarian cancer micro-environment. , 2008, Frontiers in bioscience : a journal and virtual library.

[57]  M. Tangney,et al.  Oral immune tolerance mediated by suppressor T cells may be responsible for the poorer prognosis of foregut cancers. , 2006, Medical hypotheses.

[58]  D. Carbone,et al.  VEGF as a mediator of tumor-associated immunodeficiency , 2001, Immunologic research.