Birth Size of Neonates and Its Association with Seasonality

The aim of the study is to evaluate the relationship between the season of birth and the birth weight and length of Bulgarian newborns. The weight and length data of 6517 (6098 full-term and 419 preterm) live births in 2000–2001 were collected from the birth registry of II Hospital of Obstetrics and Gynaecology “Sheynovo”, Sofia, Bulgaria. Statistical analyses were done using the SPSS 16 software for Windows: descriptive statistics; the t-test (p<0.05); One-Way ANOVA, (Tukey, HSD-test, p<0.05) and the Pearson’s correlation. The sunshine dura-tion data for 2000 and 2001 were collected at the Sofia Meteorological Station. The mean weight of Bulgarian neonates born in 2000-2001 was 3389.8 g in boys and 3261.8 g in girls. The average newborn’s length was 51.0 cm and 50.3 cm in boys and girls, respectively. In all seasons, significant gender differences were observed with a priority for boys (p≤0.001). The winter period was identified with a peak in birth length for both sexes, and spring and summer were the seasons with the lowest values for boys and girls, respectively. A significant positive correlation between birth length and the daily amount of sunshine during the prenatal period was found (p<0.001). Seasonal fluctuations influenced weight and length in Bulgarian neonates. The results obtained in this study can be useful in prenatal diagnostics, neonatal care, and health prevention of pregnant women and neonates.

[1]  Chérie E. Part,et al.  Physiological mechanisms of the impact of heat during pregnancy and the clinical implications: review of the evidence from an expert group meeting , 2022, International Journal of Biometeorology.

[2]  H. Huras,et al.  Effect of Vitamin D Supplementation on the Fetal Growth Rate in Pregnancy Complicated by Fetal Growth Restriction , 2022, Children.

[3]  T. Hajdu,et al.  Temperature, climate change, and birth weight: evidence from Hungary , 2021, Population and Environment.

[4]  S. Hajat,et al.  Associations between high temperatures in pregnancy and risk of preterm birth, low birth weight, and stillbirths: systematic review and meta-analysis , 2020, BMJ.

[5]  Chuanhua Yu,et al.  Temperature exposure during pregnancy and birth outcomes: An updated systematic review of epidemiological evidence. , 2017, Environmental pollution.

[6]  D. Viswanath,et al.  Dietary Reference Intakes for Calcium and Vitamin D , 2012, Pediatrics.

[7]  E. Hyppönen,et al.  Month of birth, vitamin D and risk of immune-mediated disease: a case control study , 2012, BMC Medicine.

[8]  G. Ebers,et al.  Seasonal Distribution of Psychiatric Births in England , 2012, PloS one.

[9]  S. Tong,et al.  The influence of season and ambient temperature on birth outcomes: a review of the epidemiological literature. , 2011, Environmental research.

[10]  S. Felix,et al.  Is cardiovascular mortality related to the season of birth?: evidence from more than 6 million cardiovascular deaths between 1992 and 2007. , 2011, Journal of the American College of Cardiology.

[11]  S. Kozieł,et al.  Association of birth weight and length with air temperature, sunlight, humidity and rainfall in the city of Warsaw, Poland. , 2010, Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen.

[12]  J. McGrath,et al.  NEONATAL VITAMIN D STATUS AND RISK OF SCHIZOPHRENIA: A POPULATION-BASED CASE-CONTROL STUDY , 2010, Schizophrenia Research.

[13]  P. Mortensen,et al.  NEONATAL VITAMIN D STATUS AND RISK OF SCHIZOPHRENIA: A POPULATION-BASED CASE-CONTROL STUDY , 2010, Schizophrenia Research.

[14]  World Medical Association (WMA),et al.  Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects , 2009, Journal of the Indian Medical Association.

[15]  B. Carstensen,et al.  Seasonality of birth in adult type 2 diabetic patients in three Ukrainian regions , 2009, Diabetologia.

[16]  L. Waller,et al.  Seasonality of Birth and Implications for Temporal Studies of Preterm Birth , 2009, Epidemiology.

[17]  E. Mayer-Davis,et al.  Association of Type 1 Diabetes With Month of Birth Among U.S. Youth , 2009, Diabetes Care.

[18]  G. Chodick,et al.  Seasonality in Birth Weight: Review of Global Patterns and Potential Causes , 2009, Human biology.

[19]  K. Koski,et al.  Association of low intake of milk and vitamin D during pregnancy with decreased birth weight , 2006, Canadian Medical Association Journal.

[20]  D. Lieberman,et al.  Seasonal fluctuations in birth weight and neonatal limb length; does prenatal vitamin D influence neonatal size and shape? , 2005, Early human development.

[21]  A. Barnett,et al.  The association between birth weight, season of birth and latitude , 2005, Annals of human biology.

[22]  P. Rothwell,et al.  Timing of birth and risk of multiple sclerosis: population based study , 2004, BMJ : British Medical Journal.

[23]  T. Cole,et al.  Birth weight and environmental heat load: a between-population analysis. , 2002, American journal of physical anthropology.

[24]  M. Bobák,et al.  The seasonality of live birth is strongly influenced by socio-demographic factors. , 2001, Human reproduction.

[25]  R. Poulton,et al.  The effects of pre- and post-natal sunlight exposure on human growth: evidence from the Southern Hemisphere. , 2000, Early human development.

[26]  R. Kumar,et al.  The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3. , 1986, Kidney international.

[27]  J. Kumari,et al.  Seasonal variation of human sex ratio at birth and the modifying factors , 1982, Indian journal of pediatrics.

[28]  O. Brooke,et al.  Intrauterine vitamin D nutrition and postnatal growth in Asian infants. , 1981, British medical journal.

[29]  S. Selvin,et al.  Four factors influencing birth weight. , 1971, British journal of preventive & social medicine.

[30]  John R. Williams DECLARATION OF HELSINKI , 1964 .

[31]  J. Severinghaus,et al.  Global climate change. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[32]  H. DeLuca,et al.  The metabolism and functions of vitamin D. , 1986, Advances in experimental medicine and biology.

[33]  J. Weiner Human biology: An introduction to human evolution, variation, growth and ecology , 1977 .

[34]  A. Hittmair,et al.  Human Biology , 1963, Nature.