Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.
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R. Collins | H. Kantarjian | M. Tallman | C. Dinardo | R. Stone | S. de Botton | A. Fathi | M. Sekeres | M. Frattini | D. Pollyea | G. Roboz | E. Attar | E. Stein | K. Macbeth | Qiang Xu | Wendy L. See | A. Tosolini | W. See
[1] I. Flinn,et al. Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib. , 2019, Blood.
[2] I. Kline,et al. Differentiation Syndrome Associated With Enasidenib, a Selective Inhibitor of Mutant Isocitrate Dehydrogenase 2: Analysis of a Phase 1/2 Study , 2018, JAMA oncology.
[3] K. Ballman,et al. Somatic mutations precede acute myeloid leukemia years before diagnosis , 2018, Nature Medicine.
[4] R. Collins,et al. Durable Remissions with Ivosidenib in IDH1‐Mutated Relapsed or Refractory AML , 2018, The New England journal of medicine.
[5] Chieh-Yu Liu,et al. Incorporation of mutations in five genes in the revised International Prognostic Scoring System can improve risk stratification in the patients with myelodysplastic syndrome , 2018, Blood Cancer Journal.
[6] R. Collins,et al. Enasidenib Monotherapy Is Effective and Well-Tolerated in Patients with Previously Untreated Mutant- IDH2 (m IDH2) Acute Myeloid Leukemia (AML) , 2017 .
[7] A. Abujamra,et al. DNA Methylation Events as Markers for Diagnosis and Management of Acute Myeloid Leukemia and Myelodysplastic Syndrome , 2017, Disease markers.
[8] R. Bejar,et al. Molecular Data and the IPSS-R: How Mutational Burden Can Affect Prognostication in MDS , 2017, Current Hematologic Malignancy Reports.
[9] P. Vyas,et al. Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response. , 2017, Blood.
[10] I. Flinn,et al. Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia. , 2017, Blood.
[11] Hua Yang,et al. AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations. , 2017, Cancer discovery.
[12] L. Pleyer,et al. Azacitidine front-line in 339 patients with myelodysplastic syndromes and acute myeloid leukaemia: comparison of French-American-British and World Health Organization classifications , 2016, Journal of Hematology & Oncology.
[13] H. Kantarjian,et al. IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression , 2015, Leukemia.
[14] V. Visconte,et al. Pathogenesis of myelodysplastic syndromes: an overview of molecular and non-molecular aspects of the disease , 2014, Blood research.
[15] P. Fenaux,et al. Outcome of patients with low-risk myelodysplasia after azacitidine treatment failure , 2013, Haematologica.
[16] B. Ko,et al. The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution. , 2012, Blood.
[17] Luca Malcovati,et al. Revised international prognostic scoring system for myelodysplastic syndromes. , 2012, Blood.
[18] M. Minden,et al. Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[19] H. Kantarjian,et al. Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. , 2011, Seminars in oncology.
[20] B. Esterni,et al. Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[21] C. Schumann,et al. Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] J. Licht,et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. , 2010, Cancer cell.
[23] J. Issa,et al. Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy , 2010, Cancer.
[24] J. Esteve,et al. Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics, outcome, and prognostic factors. , 2009, Blood.
[25] B. Cheson,et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. , 2006, Blood.
[26] Yu Shen,et al. Myelodysplastic syndrome is not merely "preleukemia". , 2002, Blood.
[27] T Hamblin,et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. , 1997, Blood.
[28] A. Tefferi,et al. Myelodysplastic syndromes. , 2009, The New England journal of medicine.
[29] F. Appelbaum,et al. Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome. , 2000, Blood.