Wastewater Testing and Detection of Poliovirus Type 2 Genetically Linked to Virus Isolated from a Paralytic Polio Case — New York, March 9–October 11, 2022

In July 2022, a case of paralytic poliomyelitis resulting from infection with vaccine-derived poliovirus (VDPV) type 2 (VDPV2)§ was confirmed in an unvaccinated adult resident of Rockland County, New York (1). As of August 10, 2022, poliovirus type 2 (PV2)¶ genetically linked to this VDPV2 had been detected in wastewater** in Rockland County and neighboring Orange County (1). This report describes the results of additional poliovirus testing of wastewater samples collected during March 9-October 11, 2022, and tested as of October 20, 2022, from 48 sewersheds (the community area served by a wastewater collection system) serving parts of Rockland County and 12 surrounding counties. Among 1,076 wastewater samples collected, 89 (8.3%) from 10 sewersheds tested positive for PV2. As part of a broad epidemiologic investigation, wastewater testing can provide information about where poliovirus might be circulating in a community in which a paralytic case has been identified; however, the most important public health actions for preventing paralytic poliomyelitis in the United States remain ongoing case detection through national acute flaccid myelitis (AFM) surveillance†† and improving vaccination coverage in undervaccinated communities. Although most persons in the United States are sufficiently immunized, unvaccinated or undervaccinated persons living or working in Kings, Orange, Queens, Rockland, or Sullivan counties, New York should complete the polio vaccination series as soon as possible.

Theresa L. Smith | Rachel L. Marine | R. Link-Gelles | T. Ng | K. St. George | D. Sugerman | E. McLanahan | G. Peacock | S. Stokley | D. Larsen | D. Lamson | F. Tobolowsky | R. Harpaz | D. Blog | C. Burns | M. Oberste | S. Wassilak | J. Jorba | N. Gerloff | Hong Sun | Elizabeth Henderson | B. Emery | J. Zucker | S. Bialek | Megan D Meldrum | D. Easton | T. Buchman | T. Gray | Shannon L. Rogers | K. McDonough | R. Ramani | Amina Dasin | T. Insaf | M. Kharfen | B. Backenson | J. Rosen | Christina J. Castro | J. Leung | Manisha Patel | Jeffrey W Mercante | K. Dooling | N. Fischer | C. Egan | S. Hughes | A. B. Ryerson | J. Laplante | S. Ostrowski | M. Fuschino | J. Santoli | S. Rulli | E. Omoregie | D. Hill | Matthew Shudt | B. Anderson | J. Routh | Ashley Tippins | D. Hoefer | G. S. Feumba | B. Gianetti | Megan Wallace | E. Yee | Stephanie D. Kovacs | Chitra Punjabi | J. Lawler | A. Kambhampati | E. Lutterloh | Grace Nabakooza | G. Cone | W. Gregg | Prabasaj Paul | J. Plitnick | Gimin Kim | Amanda Wolfe | Janine Cory | E. J. Moran | Elisabeth R. Krow-Lucal | Noelle Anderson | Mandar Mhatre | Achal Bhatt | Isaac Ravi Brenner | James McDonald | Stephen Flores | Halle Getachew | U. Bauer | Lauren Pearson | Christopher Ionta | P. S. Ruppert | Maria Souto | Kevin T McKay | I. Gelman | Eric Medina | S. Miles | E. Rosenberg | Haillie C. Meek | Hanen Belgasmi | Leanna Sayyad | Hongmei Liu | R. English | James Bullows | Ann D. Frolov | Daniel Lang | Mohammed A. Alazawi | Milagros Neyra | Nancy A. McGraw | Andrew Knecht | S. Kidd | A. López | Nina B. Masters | Barrett Brister | Alexandra Hess | Nehalraza Momin | Brianna Hanson | E. Heslin | Dana Neigel | Nicola Faraci | Natalie Migliore | Amruta Moghe | Simon Ogbamikael | Lindsey Rickerman | Erik Rist | Lynsey Schoultz | Julie Krauchuk | Angela Robertson | H. Fast | Michael D Popowich | Anna R. Hutcheson | Gul M Mustafa | N. K. Mita-Mendoza | Jed A. Augustine | Megan Baldwin | K. Barrett | Andrew Beck | Lydia J. Bennett | H. Boss | Travis Wayne Brown | K. Connelly | Blaise Cassano | Cynthia Cirillo | Adina de Coteau | A. DeSimone | F. Chauvin | Cynthia Dixey | S. Doss | Christopher R. Duggar | Christopher N. Dunham | A. Godínez | Christina Gulotta | Sarah T. Hamid | Tiffany Hammette | Liam Smith | Jonathan Hoffman | Lyndsey Hoyt | Haley R. Kappus-Kron | Genevieve N. Keys | J. Knox | James Lueken | Kevin Ma | Karen A. Mason | Elizabeth Mello | S. Miller | Tanner Morales | Jason O’Mara | Prabasaj Paul | Atefeh Paziraei | A. Pointer | Shailla J. Raymond | Cecelia A. Sanders | Justin Smith | Ashleigh Staine | Andrew J. Terranella | Bridget J. Anderson | M. Alazawi | D. Neigel | Jennifer Laplante | C. Dunham | M. Neyra | P. Ruppert | I. R. Brenner

[1]  Rachel L. Marine,et al.  Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater — New York, June–August 2022 , 2022, MMWR. Morbidity and mortality weekly report.

[2]  C. Burns,et al.  CaFÉ: A Sensitive, Low-Cost Filtration Method for Detecting Polioviruses and Other Enteroviruses in Residual Waters , 2022, Frontiers in Environmental Science.

[3]  J. Singleton,et al.  Vaccination Coverage by Age 24 Months Among Children Born in 2017 and 2018 — National Immunization Survey-Child, United States, 2018–2020 , 2021, MMWR. Morbidity and mortality weekly report.

[4]  N. Gerloff,et al.  Validation of a redesigned pan-poliovirus assay and real-time PCR platforms for the global poliovirus laboratory network , 2021, PloS one.

[5]  Lerato Seakamela,et al.  Diagnostic Assay Development for Poliovirus Eradication , 2017, Journal of Clinical Microbiology.

[6]  Updated recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding routine poliovirus vaccination. , 2009, MMWR. Morbidity and mortality weekly report.

[7]  Dallas,et al.  Poliomyelitis prevention in the United States. Updated recommendations of the Advisory Committee on Immunization Practices (ACIP). , 2000, MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports.

[8]  J. Cuthie,et al.  Serologic response to oral polio vaccine and enhanced-potency inactivated polio vaccines. , 1988, American journal of epidemiology.

[9]  D. Larsen,et al.  Using geographic information systems to link population estimates to wastewater surveillance data in New York State, USA , 2022, medRxiv.