Generation of hypothalamic neural stem cell-like cells in vitro from human pluripotent stem cells

[1]  G. Ming,et al.  Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells. , 2021, Cell stem cell.

[2]  M. Tauber,et al.  Endocrine disorders in Prader-Willi syndrome: a model to understand and treat hypothalamic dysfunction. , 2021, The lancet. Diabetes & endocrinology.

[3]  A. A. Galiakberova,et al.  Neural Stem Cells and Methods for Their Generation From Induced Pluripotent Stem Cells in vitro , 2020, Frontiers in Cell and Developmental Biology.

[4]  Xiaoqun Wang,et al.  Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus , 2020, Nature Communications.

[5]  C. Schuurmans,et al.  Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis , 2020, The Journal of Neuroscience.

[6]  Mi Yang,et al.  Reducing Hypothalamic Stem Cell Senescence Protects against Aging-Associated Physiological Decline. , 2020, Cell metabolism.

[7]  J. Takahashi,et al.  Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells. , 2020, Cell reports.

[8]  H. Arima,et al.  Tanycyte-like cells derived from mouse embryonic stem culture show hypothalamic neural stem/progenitor cell functions. , 2019, Endocrinology.

[9]  H. Arima,et al.  Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors , 2018, Scientific Reports.

[10]  Satoshi Morita,et al.  Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model , 2017, Nature.

[11]  D. Cai,et al.  Hypothalamic stem cells control aging speed partly through exosomal miRNAs , 2017, Nature.

[12]  I. Sekiya,et al.  Effects of Different Cell-Detaching Methods on the Viability and Cell Surface Antigen Expression of Synovial Mesenchymal Stem Cells , 2017, Cell transplantation.

[13]  Yi Zhang,et al.  Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity. , 2017, Cell reports.

[14]  R. Rao,et al.  Neurosarcoidosis in Pediatric Patients: A Case Report and Review of Isolated and Systemic Neurosarcoidosis. , 2016, Pediatric neurology.

[15]  M. Eiraku,et al.  Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells , 2016, Nature Communications.

[16]  T. Yoshino,et al.  Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle , 2016, Brain Structure and Function.

[17]  M. Hajihosseini,et al.  Hypothalamic tanycytes—masters and servants of metabolic, neuroendocrine, and neurogenic functions , 2015, Front. Neurosci..

[18]  M. Butler,et al.  Prader-Willi syndrome: a review of clinical, genetic, and endocrine findings , 2015, Journal of Endocrinological Investigation.

[19]  H. Müller,et al.  Neuroendocrine Disorders in Pediatric Craniopharyngioma Patients , 2015, Journal of clinical medicine.

[20]  Kinyui A. Lo,et al.  Differentiation of hypothalamic-like neurons from human pluripotent stem cells. , 2015, The Journal of clinical investigation.

[21]  D. Cai,et al.  Hypothalamic microinflammation: a common basis of metabolic syndrome and aging , 2015, Trends in Neurosciences.

[22]  J. Mchugh,et al.  Oral epithelial stem cells - implications in normal development and cancer metastasis. , 2014, Experimental cell research.

[23]  Hong Wang,et al.  Rax-CreERT2 Knock-In Mice: A Tool for Selective and Conditional Gene Deletion in Progenitor Cells and Radial Glia of the Retina and Hypothalamus , 2014, PloS one.

[24]  M. Sogayar,et al.  Existence of a potential neurogenic system in the adult human brain , 2014, Journal of Translational Medicine.

[25]  J. Flier,et al.  α-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors , 2013, Nature Communications.

[26]  S. Bellusci,et al.  Fgf10-Expressing Tanycytes Add New Neurons to the Appetite/Energy-Balance Regulating Centers of the Postnatal and Adult Hypothalamus , 2013, The Journal of Neuroscience.

[27]  G. Fishell,et al.  Tanycytes of the Hypothalamic Median Eminence Form a Diet-Responsive Neurogenic Niche , 2012, Nature Neuroscience.

[28]  J. Flier,et al.  Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice. , 2012, The Journal of clinical investigation.

[29]  Hiroyuki Miyoshi,et al.  Self-formation of functional adenohypophysis in three-dimensional culture , 2011, Nature.

[30]  H. Okano,et al.  Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice , 2011, Proceedings of the National Academy of Sciences.

[31]  S. Couillard-Després,et al.  The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival , 2011, Cell and Tissue Research.

[32]  A. Koizumi,et al.  Spatiotemporal Recapitulation of Central Nervous System Development by Murine Embryonic Stem Cell‐Derived Neural Stem/Progenitor Cells , 2008, Stem Cells.

[33]  Yoshiki Sasai,et al.  Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. , 2008, Cell stem cell.

[34]  M. Eiraku,et al.  Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation , 2008, Proceedings of the National Academy of Sciences.

[35]  O. Isacson,et al.  Markers and Methods for Cell Sorting of Human Embryonic Stem Cell‐Derived Neural Cell Populations , 2007, Stem cells.

[36]  S. Nishikawa,et al.  A ROCK inhibitor permits survival of dissociated human embryonic stem cells , 2007, Nature Biotechnology.

[37]  C. ffrench-Constant,et al.  Integrins Are Markers of Human Neural Stem Cells , 2006, Stem cells.

[38]  Radu Dobrin,et al.  Dissecting self-renewal in stem cells with RNA interference , 2006, Nature.

[39]  K. Lesch,et al.  Neural stem cell proliferation is decreased in schizophrenia, but not in depression , 2006, Molecular Psychiatry.

[40]  K. Mizuseki,et al.  Directed differentiation of telencephalic precursors from embryonic stem cells , 2005, Nature Neuroscience.

[41]  G. Rougon,et al.  mCD24 regulates proliferation of neuronal committed precursors in the subventricular zone , 2005, Molecular and Cellular Neuroscience.

[42]  S. Morrison,et al.  Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.

[43]  J. D. Macklis,et al.  Late-Stage Immature Neocortical Neurons Reconstruct Interhemispheric Connections and Form Synaptic Contacts with Increased Efficiency in Adult Mouse Cortex Undergoing Targeted Neurodegeneration , 2002, The Journal of Neuroscience.

[44]  S. Weiss,et al.  Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. , 1992, Science.