In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form.

[1]  R. Bodmeier,et al.  Solvent selection in the preparation of poly(dl-lactide) microspheres prepared by the solvent evaporation method , 1988 .

[2]  Hatem Fessi,et al.  Nanocapsule formation by interfacial polymer deposition following solvent displacement , 1989 .

[3]  M. Prosdocimi,et al.  Molecular aspects of cloricromene (AD6) distribution in human platelets and its pharmacological effects. , 1989, Thrombosis research.

[4]  C. Washington,et al.  Evaluation of non-sink dialysis methods for the measurement of drug release from colloids: effects of drug partition , 1989 .

[5]  J. Kreuter,et al.  Modification of the body distribution of poly(methyl methacrylate) nanoparticles in rats by coating with surfactants , 1990 .

[6]  C Washington,et al.  Drug release from microdisperse systems: a critical review , 1990 .

[7]  Y Tsushima,et al.  Preparation of neurotensin analogue-containing poly(dl-lactic acid) microspheres formed by oil-in-water solvent evaporation. , 1992, Journal of pharmaceutical sciences.

[8]  R. Gurny,et al.  Preparation of aqueous polymeric nanodispersions by a reversible salting-out process : influence of process parameters on particle size , 1992 .

[9]  D. Altavilla,et al.  The effect of cloricromene, a coumarine derivative, on leukocyte accumulation, myocardial necrosis and TNF-alpha production in myocardial ischaemia-reperfusion injury. , 1993, Life sciences.

[10]  Yoshiaki,et al.  Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D, L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior. , 1993 .

[11]  J. Vane,et al.  Dissociation of the anti‐ischaemic effects of cloricromene from its anti‐platelet activity , 1993, British journal of pharmacology.

[12]  Y. Kawashima,et al.  In vitro drug release behavior of D,L-lactide/glycolide copolymer (PLGA) nanospheres with nafarelin acetate prepared by a novel spontaneous emulsification solvent diffusion method. , 1994, Journal of pharmaceutical sciences.

[13]  S. Moghimi.  Mechanisms regulating body distribution of nanospheres conditioned with pluronic and tetronic block co-polymers , 1995 .

[14]  Bernhard A. Sabel,et al.  Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections , 1996, Brain Research.

[15]  M. Ueda,et al.  Optimization of the preparation of loperamide-loaded poly (L-lactide) nanoparticles by high pressure emulsification-solvent evaporation. , 1997, Journal of microencapsulation.

[16]  P. Couvreur,et al.  Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. , 1998, Journal of microencapsulation.

[17]  C. Bevilacqua,et al.  Differential inhibition of polymorphonuclear leucocyte functions by cloricromene. , 1999, Pharmacological research.

[18]  S. Davis,et al.  PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. , 1999, Journal of controlled release : official journal of the Controlled Release Society.

[19]  M. Morishita,et al.  Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method. , 1999, Drug development and industrial pharmacy.

[20]  A. R. Kulkarni,et al.  Biodegradable polymeric nanoparticles as drug delivery devices. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[21]  A. Ludwig,et al.  Preparation factors affecting the properties of polylactide nanoparticles: a factorial design study. , 2001, Die Pharmazie.

[22]  R. Müller,et al.  Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future. , 2001, Advanced drug delivery reviews.

[23]  C. Bucolo,et al.  Simultaneous determination of cloricromene and its active metabolite in rabbit aqueous humor by high-performance liquid chromatography. , 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[24]  J. Kreuter,et al.  Significant Transport of Doxorubicin into the Brain with Polysorbate 80-Coated Nanoparticles , 1999, Pharmaceutical Research.

[25]  D. A. Kharkevich,et al.  Delivery of Loperamide Across the Blood-Brain Barrier with Polysorbate 80-Coated Polybutylcyanoacrylate Nanoparticles , 1997, Pharmaceutical Research.