Combination of Heterogeneous Features for Wrist Pulse Blood Flow Signal Diagnosis via Multiple Kernel Learning

Wrist pulse signal is of great importance in the analysis of the health status and pathologic changes of a person. A number of feature extraction methods have been proposed to extract linear and nonlinear, and time and frequency features of wrist pulse signal. These features are heterogeneous in nature and are likely to contain complementary information, which highlights the need for the integration of heterogeneous features for pulse classification and diagnosis. In this paper, we propose a novel effective method to classify the wrist pulse blood flow signals by using the multiple kernel learning (MKL) algorithm to combine multiple types of features. In the proposed method, seven types of features are first extracted from the wrist pulse blood flow signals using the state-of-the-art pulse feature extraction methods, and are then fed to an efficient MKL method, SimpleMKL, to combine heterogeneous features for more effective classification. Experimental results show that the proposed method is promising in integrating multiple types of pulse features to further enhance the classification performance.

[1]  Siu Cheung Hui,et al.  Computational methods for Traditional Chinese Medicine: A survey , 2007, Comput. Methods Programs Biomed..

[2]  Max Q.-H. Meng,et al.  Robust peak detection of pulse waveform using height ratio , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[3]  Zhi,et al.  Recent Progress in Computerization of TCM , 2006 .

[4]  David Zhang,et al.  Gaussian ERP Kernel Classifier for Pulse Waveforms Classification , 2010, 2010 20th International Conference on Pattern Recognition.

[5]  David Zhang,et al.  Wavelet-based cascaded adaptive filter for removing baseline drift in pulse waveforms , 2005, IEEE Transactions on Biomedical Engineering.

[6]  Lu Wang,et al.  Pulse images recognition using fuzzy neural network , 2009, Expert Syst. Appl..

[7]  David Zhang,et al.  TCPD based pulse monitoring and analyzing , 2002, Proceedings. International Conference on Machine Learning and Cybernetics.

[8]  Michael I. Jordan,et al.  Multiple kernel learning, conic duality, and the SMO algorithm , 2004, ICML.

[9]  Nello Cristianini,et al.  A statistical framework for genomic data fusion , 2004, Bioinform..

[10]  Shiwei Li,et al.  Decision level fusion for pulse signal classification using multiple features , 2010, 2010 3rd International Conference on Biomedical Engineering and Informatics.

[11]  Huiyan Wang,et al.  A quantitative system for pulse diagnosis in Traditional Chinese Medicine , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[12]  Jason Tsong-Li Wang,et al.  Kernel design for RNA classification using Support Vector Machines , 2006, Int. J. Data Min. Bioinform..

[13]  David Zhang,et al.  Baseline wander correction in pulse waveforms using wavelet-based cascaded adaptive filter , 2007, Comput. Biol. Medicine.

[14]  Max Q.-H. Meng,et al.  Morphology Variability Analysis of Wrist Pulse Waveform for Assessment of Arteriosclerosis Status , 2008, Journal of Medical Systems.

[15]  David Zhang,et al.  Computerized Wrist Pulse Signal Diagnosis Using Modified Auto-Regressive Models , 2011, Journal of Medical Systems.

[16]  N. Huang,et al.  The empirical mode decomposition and the Hilbert spectrum for nonlinear and non-stationary time series analysis , 1998, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[17]  Nello Cristianini,et al.  Kernel Methods for Pattern Analysis , 2003, ICTAI.

[18]  Gunnar Rätsch,et al.  Large Scale Multiple Kernel Learning , 2006, J. Mach. Learn. Res..

[19]  Xuelong Li,et al.  Asymmetric bagging and random subspace for support vector machines-based relevance feedback in image retrieval , 2006, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[20]  David Zhang,et al.  Wrist pulse signal diagnosis using modified Gaussian models and Fuzzy C-Means classification. , 2009, Medical engineering & physics.

[21]  David Zhang,et al.  Time Series Classification Using Support Vector Machine with Gaussian Elastic Metric Kernel , 2010, 2010 20th International Conference on Pattern Recognition.

[22]  W. Zuo,et al.  Wrist blood flow signal-based computerized pulse diagnosis using spatial and spectrum features , 2010 .

[23]  Jeon Lee,et al.  A study on characteristics of radial arteries through ultrasonic waves , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[24]  Lei Chen,et al.  On The Marriage of Lp-norms and Edit Distance , 2004, VLDB.

[25]  George Manis,et al.  Heartbeat Time Series Classification With Support Vector Machines , 2009, IEEE Transactions on Information Technology in Biomedicine.

[26]  M.Q.-H. Meng,et al.  Pulse Image Recognition Using Fuzzy Neural Network , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[27]  Hiroaki Sakoe,et al.  A Dynamic Programming Approach to Continuous Speech Recognition , 1971 .

[28]  Richard G. Baraniuk,et al.  Tuning Support Vector Machines for Minimax and Neyman-Pearson Classification , 2008, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[29]  Lei Liu,et al.  Classification of Wrist Pulse Blood Flow Signal Using Time Warp Edit Distance , 2010, ICMB.

[30]  S M Pincus,et al.  Approximate entropy as a measure of system complexity. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[31]  Q. Mcnemar Note on the sampling error of the difference between correlated proportions or percentages , 1947, Psychometrika.

[32]  Fang-Xiang Wu,et al.  Charge State Determination of Peptide Tandem Mass Spectra Using Support Vector Machine (SVM) , 2008, IEEE Transactions on Information Technology in Biomedicine.

[33]  Pierre-François Marteau,et al.  Time Warp Edit Distance with Stiffness Adjustment for Time Series Matching , 2007, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[34]  David Zhang,et al.  Wavelet Based Analysis of Doppler Ultrasonic Wrist-pulse Signals , 2008, 2008 International Conference on BioMedical Engineering and Informatics.