Development and evaluation of tube-shaped neural probe with working channel

For brain analysis, a novel tube-shaped flexible neural probe characterize by its flexibility and stiffness with metal needle inserted into tube was fabricated and demonstrated. This probe consists of an ultra-thin polyimide tube with on outer diameter of 360μm and photofabricated recording electrodes using non-planar photofabrication technique. The probe was inserted into a rat's brain through the dura mater and successfully measured with optical stimulation.