Comparative pharmacodynamics of CYP2B induction by phenobarbital in the male and female F344/NCr rat.

[1]  J. Ward,et al.  A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats. , 1992, Biochemical pharmacology.

[2]  J. Ward,et al.  A pleiotropic response to phenobarbital-type enzyme inducers in the F344/NCr rat. Effects of chemicals of varied structure. , 1992, Biochemical pharmacology.

[3]  L. Azároff,et al.  Phenobarbital induction of cytochrome P-450 gene expression. , 1992, The Biochemical journal.

[4]  E. Schuetz,et al.  Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. , 1990, Molecular pharmacology.

[5]  R. Kato,et al.  Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone. , 1987, The Journal of biological chemistry.

[6]  M. P. Arlotto,et al.  Regulation of testosterone hydroxylation by rat liver microsomal cytochrome P-450. , 1987, Archives of biochemistry and biophysics.

[7]  P. Thomas,et al.  Monoclonal antibodies distinguish among isozymes of the cytochrome P-450b subfamily. , 1985, Archives of biochemistry and biophysics.

[8]  R. Mayer,et al.  Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. , 1985, Biochemical pharmacology.

[9]  D. Waxman,et al.  Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes. , 1985, Biochemistry.

[10]  J. W. Cameron,et al.  Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. , 1985, Archives of biochemistry and biophysics.

[11]  P. Berk,et al.  Dose-Related Effects of Phenobarbital on Hepatic Microsomal Enzymes 1 , 1983, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[12]  P. Thomas,et al.  Regio- and stereoselective metabolism of two C19 steroids by five highly purified and reconstituted rat hepatic cytochrome P-450 isozymes. , 1983, The Journal of biological chemistry.

[13]  L. Sheiner,et al.  Understanding the Dose-Effect Relationship , 1981, Clinical pharmacokinetics.

[14]  E. Glover,et al.  Species differences in responsiveness to 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene, a potent phenobarbital-like inducer of microsomal monooxygenase activity. , 1981, Molecular pharmacology.

[15]  P. Thomas,et al.  Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction. , 1981, The Journal of biological chemistry.

[16]  T. Kamataki,et al.  Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats. , 1980, Biochemical pharmacology.

[17]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[18]  S. Udenfriend,et al.  Fluorometric assay of proteins in the nanogram range. , 1973, Archives of biochemistry and biophysics.

[19]  Kato Ryuichi,et al.  Studies on the regulation of the activity of drug oxidation in rat liver microsomes by androgen and estrogen , 1970 .

[20]  E. Vesell,et al.  Sex and strain differences in basal and induced aniline hydroxylase and ethylmorphine N-demethylase activities from domestic and wild rats. , 1969, Pharmacology.

[21]  R. Stitzel,et al.  The influence of age, sex and drug treatment on microsomal drug metabolism in four rat strains. , 1969, Biochemical pharmacology.

[22]  D. Davies,et al.  Sex differences in the kinetic constants for the N-demethylation of ethylmorphine by rat liver microsomes. , 1968, Biochemical pharmacology.

[23]  R. Estabrook,et al.  Sex differences in drug metabolism by rat liver microsomes. , 1967, Molecular pharmacology.

[24]  M. Metzler,et al.  Induction of P-450 isoenzyme activities in Syrian golden hamster liver compared to rat liver as probed by the rate of 7-alkoxyresorufin-O-dealkylation. , 1988, Chemico-biological interactions.

[25]  M. Bialer,et al.  Effects of phenobarbital steady state levels on antipyrine clearance and distribution in the rat. , 1986, Biopharmaceutics & drug disposition.

[26]  T. Kamataki,et al.  Effects of phenobarbital, 3-methylcholanthrene and polychlorinated biphenyls on sex-specific forms of cytochrome P-450 in liver microsomes of rats. , 1986, Journal of biochemistry.

[27]  C. Ioannides,et al.  Drug metabolism in the ferret: effects of age, sex and strain. , 1977, General pharmacology.

[28]  R. Kato,et al.  Sex-related differences in drug metabolism. , 1974, Drug metabolism reviews.