RED CELLS , IRON , AND ERYTHROPOIESIS KLF 1 mutations are relatively more common in a thalassemia endemic region and ameliorate the severity of b-thalassemia

Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China; Department of Hematology, 303rd Hospital of the People’s Liberation Army, Nanning, Guangxi, China; Department of Birth Health and Heredity, Liuzhou Women and Children Care Hospital, Liuzhou, Guangxi, China; Prenatal Diagnostic Center, Guangxi Zhuang Autonomous Region Women and Children Care Hospital, Nanning, Guangxi, China; Department of Birth Health and Heredity, Zhuhai Women and Children Care Hospital, Zhuhai, Guangdong, China; Key Laboratory for Experimental Teratology of the Ministry of Education and Department of Medical Genetics, School of Medicine, Shandong University, Jinan, Shandong, China; and Red Cell Physiology Laboratory, New York Blood Center, New York, NY

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