Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins

[1]  J. Harvey,et al.  Invasive breast carcinoma: pathology and prognosis , 2013 .

[2]  Aung Ko Win,et al.  Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[3]  Larissa V Furtado,et al.  Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer , 2011, Genes, chromosomes & cancer.

[4]  R. Lothe,et al.  Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin , 2010, BMC Cancer.

[5]  M. Okajima,et al.  Immunohistochemical analysis of colorectal cancer with gastric phenotype: Claudin‐18 is associated with poor prognosis , 2010, Pathology international.

[6]  C. Papadimitriou,et al.  EGFR expression and activation are common in HER2 positive and triple-negative breast tumours. , 2010, Histology and histopathology.

[7]  Quan P. Ly,et al.  Gene Expression Profiling of Colorectal Mucinous Adenocarcinomas , 2010, Diseases of the colon and rectum.

[8]  S. Kakar,et al.  MUC2 gene promoter methylation in mucinous and non-mucinous colorectal cancer tissues. , 2010, International journal of oncology.

[9]  J. Potter,et al.  Lynch Syndrome–Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry , 2010, Clinical Cancer Research.

[10]  Patricia L. Blount,et al.  Intestinal Differentiation in Metaplastic, Nongoblet Columnar Epithelium in the Esophagus , 2009, The American journal of surgical pathology.

[11]  J. Kirk,et al.  Breast cancer immunohistochemistry can be useful in triage of some HNPCC families , 2009, Familial Cancer.

[12]  Li Li,et al.  High‐resolution genomic and expression analyses of copy number alterations in breast tumors , 2008, Genes, chromosomes & cancer.

[13]  A. Spurdle,et al.  Molecular, Pathologic, and Clinical Features of Early-Onset Endometrial Cancer: Identifying Presumptive Lynch Syndrome Patients , 2008, Clinical Cancer Research.

[14]  H. Vasen.  Review article: the Lynch syndrome (hereditary nonpolyposis colorectal cancer) * , 2007, Alimentary pharmacology & therapeutics.

[15]  John D Potter,et al.  Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer , 2007, Cancer Epidemiology Biomarkers & Prevention.

[16]  Michael O Woods,et al.  A new variant database for mismatch repair genes associated with Lynch syndrome , 2007, Human mutation.

[17]  S. Batra,et al.  Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases. , 2006, Biochimica et biophysica acta.

[18]  E. Osinaga,et al.  Immunohistochemical Analysis of MUC5B Apomucin Expression in Breast Cancer and Non-malignant Breast Tissues , 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[19]  K. Kawakami,et al.  BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status , 2006, Molecular Cancer.

[20]  P. Westenend,et al.  Breast cancer in an MSH2 gene mutation carrier. , 2005, Human pathology.

[21]  I. Ellis,et al.  Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer , 2005, Modern Pathology.

[22]  W. Gerald,et al.  EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations , 2005, Modern Pathology.

[23]  R. Odze,et al.  Utility of immunohistochemistry in distinguishing primary adenocarcinomas from metastatic breast carcinomas in the gastrointestinal tract. , 2005, Archives of pathology & laboratory medicine.

[24]  K. Aben,et al.  More Differences Between HNPCC-related and Sporadic Carcinomas From the Endometrium as Compared to the Colon , 2004, The American journal of surgical pathology.

[25]  M. Di Maio,et al.  Loss of hMSH2 expression in primary breast cancer with p53 alterations. , 2004, Oncology reports.

[26]  D. Silberg,et al.  Human MUC2 Mucin Gene Is Transcriptionally Regulated by Cdx Homeodomain Proteins in Gastrointestinal Carcinoma Cell Lines* , 2003, Journal of Biological Chemistry.

[27]  W. Gerald,et al.  Value of Histopathology in Predicting Microsatellite Instability in Hereditary Nonpolyposis Colorectal Cancer and Sporadic Colorectal Cancer , 2003, The American journal of surgical pathology.

[28]  I. Stewart,et al.  Histopathology and Mismatch Repair Status of 458 Consecutive Colorectal Carcinomas , 2003, The American journal of surgical pathology.

[29]  Nikolaos Kavantzas,et al.  Immunohistochemical evaluation of immune response in invasive ductal breast cancer of not-otherwise-specified type. , 2003, Breast.

[30]  A. Gown,et al.  CDX2, a Highly Sensitive and Specific Marker of Adenocarcinomas of Intestinal Origin: An Immunohistochemical Survey of 476 Primary and Metastatic Carcinomas , 2003, The American journal of surgical pathology.

[31]  E. Osinaga,et al.  Detection of bone marrow‐disseminated breast cancer cells using an RT‐PCR assay of MUC5B mRNA , 2003, International journal of cancer.

[32]  T. Irimura,et al.  Expression of mucins (MUC1, MUC2, MUC5AC and MUC6) in mucinous carcinoma of the breast: comparison with invasive ductal carcinoma , 2003, Histopathology.

[33]  D. Silberg,et al.  Expression of intestine‐specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas , 2003, The Journal of pathology.

[34]  P. Propping,et al.  Loss of DNA Mismatch Repair Proteins in Skin Tumors From Patients With Muir–Torre Syndrome and MSH2 or MLH1 Germline Mutations: Establishment of Immunohistochemical Analysis as a Screening Test , 2002, The American journal of surgical pathology.

[35]  J. Palazzo,et al.  Exclusion of breast cancer as an integral tumor of hereditary nonpolyposis colorectal cancer. , 2002, Cancer research.

[36]  H. Morreau,et al.  Is breast cancer part of the tumor spectrum of hereditary nonpolyposis colorectal cancer? , 2001, American journal of human genetics.

[37]  A. Viel,et al.  Four novel MSH2 and MLH1 frameshift mutations and occurrence of a breast cancer phenocopy in hereditary nonpolyposis colorectal cancer , 2001, Human mutation.

[38]  F. Schmitt,et al.  Immunohistochemical study of the expression of MUC5AC and MUC6 in breast carcinomas and adjacent breast tissues , 2001, Journal of clinical pathology.

[39]  B. Leggett,et al.  Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[40]  D. Schaid,et al.  Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: Associations with family history and histopathology , 2000, International journal of cancer.

[41]  D. Quinn,et al.  Microsatellite instability markers in breast cancer: A review and study showing MSI was not detected at ‘BAT 25’ and ‘BAT 26’ microsatellite markers in early-onset breast cancer , 2000, Breast Cancer Research and Treatment.

[42]  T. Motoyama,et al.  Mucinous carcinoma of the breast: A multifaceted study with special reference to histogenesis and neuroendocrine differentiation , 1999, Pathology international.

[43]  J. Chu,et al.  Mucin expression in mucinous carcinoma and other invasive carcinomas of the breast. , 1999, Cancer letters.

[44]  F. Real,et al.  MUC6 expression in breast tissues and cultured cells: Abnormal expression in tumors and regulation by steroid hormones , 1998, International journal of cancer.

[45]  H. Stein,et al.  Overexpression or ectopic expression of MUC2 is the common property of mucinous carcinomas of the colon, pancreas, breast, and ovary , 1997, The Journal of pathology.

[46]  J. Boyd,et al.  Molecular genetic evidence of the occurrence of breast cancer as an integral tumor in patients with the hereditary nonpolyposis colorectal carcinoma syndrome , 1996, Cancer.

[47]  J. Gudmundsson,et al.  Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non‐polyposis colon cancer trait , 1995, Clinical genetics.

[48]  M. McGuckin,et al.  Expression of MUC2 epithelial mucin in breast carcinoma. , 1993, Journal of clinical pathology.

[49]  R. Dahiya,et al.  Heterogeneity of mucin gene expression in normal and neoplastic tissues. , 1993, Cancer research.

[50]  C. Elston,et al.  THE ASSESSMENT OF HISTOLOGICAL DIFFERENTIATION IN BREAST CANCER , 1984 .

[51]  A. Sahin,et al.  Invasive Breast Carcinoma , 2014 .

[52]  J. Reis-Filho,et al.  Absence of microsatellite instability in mucinous carcinomas of the breast. , 2010, International journal of clinical and experimental pathology.

[53]  A. Lopes,et al.  Frequency of extra-colonic tumors in hereditary nonpolyposis colorectal cancer (HNPCC) and familial colorectal cancer (FCC) Brazilian families: An analysis by a Brazilian Hereditary Colorectal Cancer Institutional Registry , 2004, Familial Cancer.

[54]  J. Boyd,et al.  Male breast cancer in the hereditary nonpolyposis colorectal cancer syndrome , 2004, Breast Cancer Research and Treatment.

[55]  E. Berg,et al.  World Health Organization Classification of Tumours , 2002 .

[56]  R. Scott,et al.  Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds. , 2001, American journal of human genetics.