DSM: A Deep Supervised Multi-Scale Network Learning for Skin Cancer Segmentation

The automatic segmentation of the skin lesion on dermoscopy images is an important step for diagnosing the melanoma. However, the skin lesion segmentation is still a challenging task due to the blur lesion border, low contrast between the skin cancer region and normal tissue background, and various sizes of cancer regions. In this paper, we propose a deep supervised multi-scale network (DSM-Network), which achieves satisfied skin cancer segmentation result by utilizing the side-output layers of the network to aggregate information from shallow&deep layers, and designing a multi-scale connection block to handle a variety of cancer sizes’ changes. Moreover, a post-processing of the contour refinement strategy is adopted by a conditional random field (CRF) model to further improve the segmentation results. Extensive experiments on two public datasets: ISBI 2017 and PH2 have demonstrated that our designed DSM-Network has gained competitive performance compared with other state-of-the-art methods.

[1]  Gerald Schaefer,et al.  Lesion border detection in dermoscopy images , 2009, Comput. Medical Imaging Graph..

[2]  Radu Ciprian Bilcu,et al.  Constrained Unsharp Masking for Image Enhancement , 2008, ICISP.

[3]  Emmanuelle Gouillart,et al.  scikit-image: image processing in Python , 2014, PeerJ.

[4]  Sharath Pankanti,et al.  Deep learning ensembles for melanoma recognition in dermoscopy images , 2016, IBM J. Res. Dev..

[5]  Alan C. Bovik,et al.  Automatic segmentation of dermoscopy images using self-generating neural networks seeded by genetic algorithm , 2013, Pattern Recognit..

[6]  Pedro M. Ferreira,et al.  PH2 - A dermoscopic image database for research and benchmarking , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[7]  Jian Sun,et al.  Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[8]  Chunming Li,et al.  Minimization of Region-Scalable Fitting Energy for Image Segmentation , 2008, IEEE Transactions on Image Processing.

[9]  Niloofar Gheissari,et al.  Segmentation of Dermoscopy Images Using Wavelet Networks , 2013, IEEE Transactions on Biomedical Engineering.

[10]  Ron Kimmel,et al.  Efficient Dilation, Erosion, Opening and Closing Algorithms , 2000, ISMM.

[11]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[12]  A. Jemal,et al.  Cancer statistics, 2016 , 2016, CA: a cancer journal for clinicians.

[13]  Gerald Schaefer,et al.  An ensemble classification approach for melanoma diagnosis , 2014, Memetic Computing.

[14]  Roberto Cipolla,et al.  SegNet: A Deep Convolutional Encoder-Decoder Architecture for Image Segmentation , 2015, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[15]  David Dagan Feng,et al.  Automatic Skin Lesion Analysis using Large-scale Dermoscopy Images and Deep Residual Networks , 2017, ArXiv.

[16]  LinLin Shen,et al.  Skin Lesion Analysis towards Melanoma Detection Using Deep Learning Network , 2017, Sensors.

[17]  Hazim Kemal Ekenel,et al.  DermoNet: densely linked convolutional neural network for efficient skin lesion segmentation , 2019, EURASIP J. Image Video Process..

[18]  Junji Maeda,et al.  Comparison of Segmentation Methods for Melanoma Diagnosis in Dermoscopy Images , 2009, IEEE Journal of Selected Topics in Signal Processing.

[19]  Xuelong Li,et al.  Mean shift based gradient vector flow for image segmentation , 2013, Comput. Vis. Image Underst..

[20]  John Willian Branch,et al.  Automatic skin lesion segmentation on dermoscopic images by the means of superpixel merging , 2018, MICCAI.

[21]  Mun-Taek Choi,et al.  Skin lesion segmentation in dermoscopy images via deep full resolution convolutional networks , 2018, Comput. Methods Programs Biomed..

[22]  Rahil Garnavi,et al.  Sparse Coding Based Skin Lesion Segmentation Using Dynamic Rule-Based Refinement , 2016, MLMI@MICCAI.

[23]  Noel C. F. Codella,et al.  Skin lesion analysis toward melanoma detection: A challenge at the 2017 International symposium on biomedical imaging (ISBI), hosted by the international skin imaging collaboration (ISIC) , 2016, 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018).

[24]  Michael R Hamblin,et al.  CA : A Cancer Journal for Clinicians , 2011 .

[25]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[26]  Gerald Schaefer,et al.  Lesion Border Detection in Dermoscopy Images Using Ensembles of Thresholding Methods , 2013, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[27]  Yading Yuan,et al.  Improving Dermoscopic Image Segmentation With Enhanced Convolutional-Deconvolutional Networks , 2017, IEEE Journal of Biomedical and Health Informatics.

[28]  Petia Radeva,et al.  SLSDeep: Skin Lesion Segmentation Based on Dilated Residual and Pyramid Pooling Networks , 2018, MICCAI.

[29]  A. Taleb-Ahmed,et al.  Extraction of specific parameters for skin tumour classification , 2009, Journal of medical engineering & technology.

[30]  R. H. Moss,et al.  A relative color approach to color discrimination for malignant melanoma detection in dermoscopy images , 2007, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[31]  Qaisar Abbas,et al.  Lesion border detection in dermoscopy images using dynamic programming , 2011, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[32]  Ghassan Hamarneh,et al.  Star Shape Prior in Fully Convolutional Networks for Skin Lesion Segmentation , 2018, MICCAI.

[33]  Yading Yuan,et al.  Automatic Skin Lesion Segmentation Using Deep Fully Convolutional Networks With Jaccard Distance , 2017, IEEE Transactions on Medical Imaging.

[34]  Vladlen Koltun,et al.  Efficient Inference in Fully Connected CRFs with Gaussian Edge Potentials , 2011, NIPS.

[35]  Hang Li,et al.  Dense Deconvolutional Network for Skin Lesion Segmentation , 2019, IEEE Journal of Biomedical and Health Informatics.