Quantitative measurements of proton spin‐lattice (T1) and spin–spin (T2) relaxation times in the mouse brain at 7.0 T

The goal of this work is to provide regional T1 and T2 values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T1 in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T2 measurements were made in the same regions using a single spin echo sequence repeated at six separate echo times. Both T1 and T2 measurements were validated with phantom measurements. Magn Reson Med 49:576–580, 2003. © 2003 Wiley‐Liss, Inc.

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