Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes

[1]  Neng-wei Yu,et al.  Impact of Insulin Sensitizers on the Incidence of Dementia: A Meta-Analysis , 2016, Dementia and Geriatric Cognitive Disorders.

[2]  Hongyue Dai,et al.  A candidate plasma protein classifier to identify Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.

[3]  Martina Sattlecker,et al.  Are blood-based protein biomarkers for Alzheimer's disease also involved in other brain disorders? A systematic review. , 2014, Journal of Alzheimer's disease : JAD.

[4]  Magda Tsolaki,et al.  Circulating Proteomic Signatures of Chronological Age , 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

[5]  P. Sachdev,et al.  DNA methylation in the apolipoprotein-A1 gene is associated with episodic memory performance in healthy older individuals. , 2015, Journal of Alzheimer's disease : JAD.

[6]  Magda Tsolaki,et al.  Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology , 2014, Alzheimer's & Dementia.

[7]  Magda Tsolaki,et al.  Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. , 2013, Journal of Alzheimer's disease : JAD.

[8]  Nick C Fox,et al.  Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.

[9]  P. Crane,et al.  Alzheimer’s Disease: Analyzing the Missing Heritability , 2013, PloS one.

[10]  Stephen H. D. Jackson,et al.  Cognitive Change in Older Women Using a Computerised Battery: A Longitudinal Quantitative Genetic Twin Study , 2013, Behavior genetics.

[11]  P. Aisen,et al.  Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease , 2013, Nature Reviews Drug Discovery.

[12]  C. Rowe,et al.  Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study , 2013, The Lancet Neurology.

[13]  Simone Lista,et al.  Blood and plasma-based proteomic biomarker research in Alzheimer's disease , 2013, Progress in Neurobiology.

[14]  Naomi R. Wray,et al.  Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis , 2012, Human molecular genetics.

[15]  E. Nasonov,et al.  Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the treatment of rheumatoid arthritis: a phase II, randomised, double-blind, placebo-controlled, multicentre trial , 2012, Annals of the rheumatic diseases.

[16]  P. Zürbig,et al.  Use of proteomic methods in the analysis of human body fluids in Alzheimer research , 2012, Electrophoresis.

[17]  Alireza Moayyeri,et al.  The UK Adult Twin Registry (TwinsUK Resource) , 2012, Twin Research and Human Genetics.

[18]  Dorret I. Boomsma,et al.  The continuing value of twin studies in the omics era , 2012, Nature Reviews Genetics.

[19]  Magda Tsolaki,et al.  Identification of cis-regulatory variation influencing protein abundance levels in human plasma. , 2012, Human molecular genetics.

[20]  A. Simmons,et al.  Regional Magnetic Resonance Imaging Measures for Multivariate Analysis in Alzheimer’s Disease and Mild Cognitive Impairment , 2012, Brain Topography.

[21]  Ping Xu,et al.  The Loss of c-Jun N-Terminal Protein Kinase Activity Prevents the Amyloidogenic Cleavage of Amyloid Precursor Protein and the Formation of Amyloid Plaques In Vivo , 2011, The Journal of Neuroscience.

[22]  Mattias Rantalainen,et al.  Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model , 2011, Proteome Science.

[23]  Magda Tsolaki,et al.  AddNeuroMed and ADNI: Similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America , 2011, NeuroImage.

[24]  A. Hofman,et al.  Serum levels of pregnancy zone protein are elevated in presymptomatic Alzheimer's disease. , 2011, Journal of proteome research.

[25]  K. Christensen,et al.  Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422 , 2011, Molecular and Cellular Biochemistry.

[26]  John Fox,et al.  OpenMx: An Open Source Extended Structural Equation Modeling Framework , 2011, Psychometrika.

[27]  D. Louis Collins,et al.  Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls , 2011, NeuroImage.

[28]  Magda Tsolaki,et al.  The AddNeuroMed framework for multi‐centre MRI assessment of Alzheimer's disease : experience from the first 24 months , 2011, International journal of geriatric psychiatry.

[29]  D. Selkoe Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[30]  L. Ferrucci,et al.  Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals. , 2011, Journal of Alzheimer's disease : JAD.

[31]  Rachel Ostroff,et al.  Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery , 2010, PLoS ONE.

[32]  Tracy R. Keeney,et al.  Aptamer-based multiplexed proteomic technology for biomarker discovery , 2010, Nature Precedings.

[33]  Jean-Luc Anton,et al.  Region of interest analysis using an SPM toolbox , 2010 .

[34]  A. Simmons,et al.  AddNeuroMed—The European Collaboration for the Discovery of Novel Biomarkers for Alzheimer's Disease , 2009, Annals of the New York Academy of Sciences.

[35]  A. Simmons,et al.  MRI Measures of Alzheimer's Disease and the AddNeuroMed Study , 2009, Annals of the New York Academy of Sciences.

[36]  John Ashburner,et al.  A fast diffeomorphic image registration algorithm , 2007, NeuroImage.

[37]  S Lovestone,et al.  Biomarkers for disease modification trials--the innovative medicines initiative and AddNeuroMed. , 2007, The journal of nutrition, health & aging.

[38]  J. Yates,et al.  PRAK Is Essential for ras-Induced Senescence and Tumor Suppression , 2007, Cell.

[39]  John B Carlin,et al.  Regression models for twin studies: a critical review. , 2005, International journal of epidemiology.

[40]  Marc M Budge,et al.  Predicting cognitive decline in healthy older adults. , 2005, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[41]  Karl J. Friston,et al.  Unified segmentation , 2005, NeuroImage.

[42]  J. Hanley,et al.  Statistical analysis of correlated data using generalized estimating equations: an orientation. , 2003, American journal of epidemiology.

[43]  D. Bennett,et al.  From Healthy Aging to Early Alzheimer's Disease: In Vivo Detection of Entorhinal Cortex Atrophy , 2000, Annals of the New York Academy of Sciences.

[44]  S. Lovestone,et al.  UK Alzheimer's Disease Genetics Consortium , 1999, International journal of geriatric psychiatry.

[45]  P. Bucy National Institute of Neurological and Communicative Disorders and Stroke , 1975, Surgical Neurology.