Adjuvant radiotherapy for rectal cancer: a systematic overview of 8507 patients from 22 randomised trials

[1]  H. Putter,et al.  Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. , 2001, The New England journal of medicine.

[2]  A. Lindblad,et al.  Adjuvant postoperative radiotherapy and chemotherapy in rectal carcinoma: a review of the Gastrointestinal Tumor Study Group experience. , 1988, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[3]  M. Buyse,et al.  Preoperative Radiotherapy as Adjuvant Treatment in Rectal Cancer: Final Results of a Randomized Study of the European Organization for Research and Treatment of Cancer (EORTC) , 1988, Annals of surgery.

[4]  W. Niebel,et al.  Five-year results of a prospective and randomized study: experience with combined radiotherapy and surgery of primary rectal carcinoma. , 1988, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

[5]  Adjuvant post-operative radiotherapy in rectal cancer: results from the ANZ Bowel Cancer Trial (Protocol 8202). , 1991, Australasian radiology.

[6]  L. Påhlman,et al.  Preoperative or postoperative irradiation in adenocarcinoma of the rectum: Final treatment results of a randomized trial and an evaluation of late secondary effects , 1993, Diseases of the colon and rectum.

[7]  A R Feinstein,et al.  The Will Rogers phenomenon. Stage migration and new diagnostic techniques as a source of misleading statistics for survival in cancer. , 1985, The New England journal of medicine.

[8]  S. Love,et al.  Long-term results of a randomised trial of short-course low-dose adjuvant pre-operative radiotherapy for rectal cancer: reduction in local treatment failure. , 1994, European journal of cancer.

[9]  L. Påhlman,et al.  Initial report from a Swedish multicentre study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma , 1993, The British journal of surgery.

[10]  Rider Wd,et al.  Preoperative irradiation in operable cancer of the rectum: report of the Toronto trial. , 1977 .

[11]  W. H. Bond,et al.  The evaluation of low dose pre‐operative X‐ray therapy in the management of operable rectal cancer; results of a randomly controlled trial , 1984, The British journal of surgery.

[12]  J. M. Taylor,et al.  Dose-response relationship for radiation therapy of subclinical disease. , 1995, International journal of radiation oncology, biology, physics.

[13]  R. Gelber,et al.  Improved methodology for analyzing local and distant recurrence. , 1990, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  B. Cummings Radiation therapy and rectal carcinoma: The Princess Margaret Hospital experience , 1985, The British journal of surgery.

[15]  M. Yasutomi,et al.  [Comparison of surgical therapy and combined irradiation in rectal cancer--first report, effect of irradiation on the tumor. Study Group of Surgical Therapy and Combined Irradiation in Rectal Cancer]. , 1989, Gan to kagaku ryoho. Cancer & chemotherapy.

[16]  P. Quirke,et al.  LOCAL RECURRENCE OF RECTAL ADENOCARCINOMA DUE TO INADEQUATE SURGICAL RESECTION Histopathological Study of Lateral Tumour Spread and Surgical Excision , 1986, The Lancet.

[17]  J. Conn,et al.  Preoperative radiotherapy for colorectal cancer. , 1975 .

[18]  R. Heald,et al.  RECURRENCE AND SURVIVAL AFTER TOTAL MESORECTAL EXCISION FOR RECTAL CANCER , 1986, The Lancet.

[19]  J. Overgaard,et al.  Postoperative radiotherapy in Dukes' B and C carcinoma of the rectum and rectosigmoid: A randomized multicenter study , 1986, Cancer.

[20]  J. Fowler The linear-quadratic formula and progress in fractionated radiotherapy. , 1989, The British journal of radiology.

[21]  R. James,et al.  Adjuvant preoperative radiotherapy for locally advanced rectal carcinoma , 1994, Diseases of the colon and rectum.

[22]  H. Johansson,et al.  The Stockholm I trial of preoperative short term radiotherapy in operable rectal carcinoma , 1995, Cancer.

[23]  M. Kligerman Preoperative radiation therapy in rectal cancer , 1975 .

[24]  H. Rockette,et al.  Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02. , 2000, Journal of the National Cancer Institute.

[25]  A. Horn,et al.  Low‐dose preoperative radiation postpones recurrences in operable rectal cancer: Results of a randomized multicenter trial in western norway , 1990, Cancer.

[26]  R. Dale,et al.  Mathematical models of tumour and normal tissue response. , 1999, Acta oncologica.

[27]  S. Doggett,et al.  RTOG 81-15 ECOG 83-23 evaluation of preoperative radiation therapy in operable rectal carcinoma , 1993 .

[28]  H. Rockette,et al.  Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01. , 1988, Journal of the National Cancer Institute.

[29]  L Påhlman,et al.  Improved survival with preoperative radiotherapy in resectable rectal cancer. , 1997, The New England journal of medicine.

[30]  G. Higgins,et al.  Preoperative radiation and surgery for cancer of the rectum: Veterans administration surgical oncology group trial II , 1986, Cancer.

[31]  L. Rutqvist,et al.  Adjuvant preoperative radiotherapy in patients with rectal carcinoma: Adverse effects during long term follow‐up of two randomized trials , 1996, Cancer.