Does Physical Activity Increase Life Expectancy? A Review of the Literature

Physical activity reduces many major mortality risk factors including arterial hypertension, diabetes mellitus type 2, dyslipidemia, coronary heart disease, stroke, and cancer. All-cause mortality is decreased by about 30% to 35% in physically active as compared to inactive subjects. The purpose of this paper was to synthesize the literature on life expectancy in relation to physical activity. A systematic PubMed search on life expectancy in physically active and inactive individuals was performed. In addition, articles comparing life expectancy of athletes compared to that of nonathletes were reviewed. Results of 13 studies describing eight different cohorts suggest that regular physical activity is associated with an increase of life expectancy by 0.4 to 6.9 years. Eleven studies included confounding risk factors for mortality and revealed an increase in life expectancy by 0.4 to 4.2 years with regular physical activity. Eleven case control studies on life expectancy in former athletes revealed consistently greater life expectancy in aerobic endurance athletes but inconsistent results for other athletes. None of these studies considered confounding risk factors for mortality. In conclusion, while regular physical activity increases life expectancy, it remains unclear if high-intensity sports activities further increase life expectancy.

[1]  S. Straus,et al.  New evidence for stroke prevention: scientific review. , 2002, JAMA.

[2]  C. Prout Life expectancy of college oarsmen. , 1972, JAMA.

[3]  Chaoyang Li,et al.  Low-risk lifestyle behaviors and all-cause mortality: findings from the National Health and Nutrition Examination Survey III Mortality Study. , 2011, American journal of public health.

[4]  G. Kelley,et al.  Aerobic exercise and HDL2-C: a meta-analysis of randomized controlled trials. , 2006, Atherosclerosis.

[5]  R. Colagiuri,et al.  Diet and exercise in the prevention of diabetes. , 2010, Journal of human nutrition and dietetics : the official journal of the British Dietetic Association.

[6]  R S Paffenbarger,et al.  The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. , 1993, The New England journal of medicine.

[7]  J. Berthelot,et al.  Gender Differences in Disability-Free Life Expectancy for Selected Risk Factors and Chronic Conditions in Canada , 2002, Journal of women & aging.

[8]  J. Kaprio,et al.  Increased life expectancy of world class male athletes. , 1993, Medicine and science in sports and exercise.

[9]  A. Rook An Investigation into the Longevity of Cambridge Sportsmen , 1954, British medical journal.

[10]  R. Paffenbarger,et al.  Physical activity, all-cause mortality, and longevity of college alumni. , 1986, The New England journal of medicine.

[11]  G. Fraser,et al.  Ten years of life: Is it a matter of choice? , 2001, Archives of internal medicine.

[12]  D. Kromhout,et al.  Determinants of longevity and all-cause mortality among middle-aged men. Role of 48 personal characteristics in a 40-year follow-up of Italian Rural Areas in the Seven Countries Study , 2006, Aging clinical and experimental research.

[13]  D. Corella,et al.  Increased Average Longevity among the “Tour de France” Cyclists , 2011, International journal of sports medicine.

[14]  S. Ebrahim,et al.  Multiple risk factor interventions for primary prevention of coronary heart disease. , 2000, The Cochrane database of systematic reviews.

[15]  J. J. Rivera,et al.  Effects of physical activity on cardiovascular disease. , 2012, The American journal of cardiology.

[16]  Suzanne G. Leveille,et al.  Smoking, physical activity, and active life expectancy. , 1999, American journal of epidemiology.

[17]  H. Montoye,et al.  Study of the longevity and morbidity of college athletes. , 1956, Journal of the American Medical Association.

[18]  B. Saltin,et al.  Evidence for prescribing exercise as therapy in chronic disease , 2006, Scandinavian journal of medicine & science in sports.

[19]  D. Voskuil,et al.  Physical Activity and Breast Cancer: A Systematic Review , 2007, Epidemiology.

[20]  M. Kruger,et al.  Longevity of Major League Baseball Players , 2005, Statistical bulletin.

[21]  P. Martelletti,et al.  The role of physical activity in the prevention and treatment of chronic diseases. , 2010, La Clinica terapeutica.

[22]  M. Karvonen ENDURANCE SPORTS, LONGEVITY, AND HEALTH , 1977, Annals of the New York Academy of Sciences.

[23]  S. Blair,et al.  Combined impact of lifestyle factors on cancer mortality in men. , 2011, Annals of epidemiology.

[24]  W Gordon THE INFLUENCE OF STRONG, PREVALENT, RAIN-BEARING WINDS ON THE COURSE OF PHTHISIS , 1912, British medical journal.

[25]  D. Warburton,et al.  Health benefits of physical activity: the evidence , 2006, Canadian Medical Association Journal.

[26]  Wilma J Nusselder,et al.  Physical activity and life expectancy with and without diabetes: life table analysis of the Framingham Heart Study. , 2006, Diabetes care.

[27]  M. Kruger,et al.  The Longevity of Baseball Hall of Famers Compared to Other Players , 2005, Death studies.

[28]  R. Paffenbarger,et al.  Physical activity, other life-style patterns, cardiovascular disease and longevity. , 2009, Acta medica Scandinavica. Supplementum.

[29]  R S Paffenbarger,et al.  Changes in physical activity and other lifeway patterns influencing longevity. , 1994, Medicine and science in sports and exercise.

[30]  C. Ulrich,et al.  [Physiologic and molecular mechanisms linking physical activity to cancer risk and progression]. , 2012, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

[31]  Juha Pekkanen,et al.  REDUCTION OF PREMATURE MORTALITY BY HIGH PHYSICAL ACTIVITY: A 20-YEAR FOLLOW-UP OF MIDDLE-AGED FINNISH MEN , 1987, The Lancet.

[32]  Xueliang Li,et al.  On a Relation Between , 2012 .

[33]  J. Wiskemann,et al.  Physiologische und molekulare Mechanismen der Wirkung von körperlicher Aktivität auf das Krebsrisiko und den Verlauf einer Krebserkrankung , 2011, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz.

[34]  A. Ahlbom,et al.  Golf: a game of life and death – reduced mortality in Swedish golf players , 2009, Scandinavian journal of medicine & science in sports.

[35]  O. Kuss,et al.  Longevity of soccer players: an investigation of all German internationals from 1908 to 2006 , 2011, Scandinavian journal of medicine & science in sports.

[36]  J. Kaprio,et al.  Life Expectancy of Former Elite Athletes , 1994, Sports medicine.

[37]  M. Karvonen,et al.  Longevity of endurance skiers. , 1974, Medicine and science in sports.

[38]  M. Halle,et al.  Physical activity in the prevention and treatment of colorectal carcinoma. , 2009, Deutsches Arzteblatt international.

[39]  Hui Ting Chan,et al.  Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study , 2011, The Lancet.

[40]  O. Franco,et al.  The relation between non-occupational physical activity and years lived with and without disability , 2008, Journal of Epidemiology & Community Health.

[41]  Matthias Egger,et al.  Domains of physical activity and all-cause mortality: systematic review and dose-response meta-analysis of cohort studies. , 2011, International journal of epidemiology.

[42]  Mustafa Atalay,et al.  Exercise plays a preventive role against Alzheimer's disease. , 2010, Journal of Alzheimer's disease : JAD.

[43]  O. Franco,et al.  Living healthier for longer: Comparative effects of three heart-healthy behaviors on life expectancy with and without cardiovascular disease , 2009, BMC public health.

[44]  D. Warburton,et al.  A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults , 2010, The international journal of behavioral nutrition and physical activity.