Risk factors for development of diabetes mellitus, hypertension and dyslipidemia.

We investigated the risk factors for the development of diabetes mellitus, hypertension and dyslipidemia simultaneously in a community-based observational cohort study (n=4304). When hypertension or dyslipidemia was present at baseline, hazard ratio (95% CI) of developing diabetes mellitus at year 5 is 3.014 (2.131-4.264) or 2.112 (1.520-2.936), respectively.

[1]  Yasuo Ohashi,et al.  Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials , 2010, The Lancet.

[2]  O. Augusto,et al.  Peroxynitrite-mediated formation of free radicals in human plasma: EPR detection of ascorbyl, albumin-thiyl and uric acid-derived free radicals. , 1996, The Biochemical journal.

[3]  J. Pickup,et al.  NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X , 1997, Diabetologia.

[4]  S. Anker,et al.  Relation between serum uric acid and lower limb blood flow in patients with chronic heart failure. , 1997, Heart.

[5]  A. Folsom,et al.  Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects--Atherosclerosis Risk in Communities Study. , 2007, Archives of internal medicine.

[6]  D. Jacobs,et al.  ReviewIs Serum Gamma Glutamyltransferase a Marker of Oxidative Stress? , 2004, Free radical research.

[7]  G. Mancia.  Blood pressure reduction and cardiovascular outcomes: past, present, and future. , 2007, The American journal of cardiology.

[8]  B. Howard,et al.  Diabetes and cardiovascular disease , 2000, Annual review of medicine.

[9]  P. Chou,et al.  Long-term effects of antihypertensive drugs on the risk of new-onset diabetes in elderly Taiwanese hypertensives. , 2008, International heart journal.

[10]  S. Anker,et al.  Serum uric acid as an index of impaired oxidative metabolism in chronic heart failure. , 1997, European heart journal.

[11]  G. Sanford,et al.  Lipids, lipoproteins and coronary heart disease in minority populations. , 1994, Atherosclerosis.

[12]  D. Jacobs,et al.  Association of serum carotenoids and tocopherols with gamma-glutamyltransferase: the Cardiovascular Risk Development in Young Adults (CARDIA) Study. , 2004, Clinical chemistry.

[13]  M. A. Crook,et al.  Is Type II diabetes mellitus a disease of the innate immune system? , 1998, Diabetologia.

[14]  G. Siest,et al.  gamma-Glutamyltransferase dependent generation of reactive oxygen species from a glutathione/transferrin system. , 1998, Free radical biology & medicine.

[15]  J. Ellis,et al.  Cardiovascular disease risk factors in native Americans: a literature review. , 1994, American journal of preventive medicine.