Contribution of cytochrome P-4502 D 6 phenotype to the neuromodulatory effects of dextromethorphan DESMEULES ,
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[1] D. Stillman. High-dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia , 1997 .
[2] A. Malmberg,et al. Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. , 1997, The Journal of pharmacology and experimental therapeutics.
[3] G. Steinberg,et al. Dose escalation safety and tolerance study of the N-methyl-D-aspartate antagonist dextromethorphan in neurosurgery patients. , 1996, Journal of neurosurgery.
[4] V. Kimiskidis,et al. Pharmacokinetics of dextromethorphan and dextrorphan in epileptic patients , 1996, Acta neurologica Scandinavica.
[5] A. Pertovaara,et al. An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist , 1995, Pharmacology Biochemistry and Behavior.
[6] L. Arendt-Nielsen,et al. Facilitation of the human nociceptive reflex by stimulation of A beta-fibres in a secondary hyperalgesic area sustained by nociceptive input from the primary hyperalgesic area. , 1995, Acta physiologica Scandinavica.
[7] E. Sellers,et al. Effects of route of administration on dextromethorphan pharmacokinetics and behavioral response in the rat. , 1995, The Journal of pharmacology and experimental therapeutics.
[8] F. Tortella,et al. σ receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures , 1995, Brain Research.
[9] D. Price,et al. The N-methyl-d-aspartate receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man , 1994, Pain.
[10] A. Jadad,et al. Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design , 1994, Pain.
[11] G. Bennett,et al. Neuropathic pain sensations are differentially sensitive to dextrorphan , 1994, Neuroreport.
[12] M. Koltzenburg,et al. Nociceptor modulated central sensitization causes mechanical hyperalgesia in acute chemogenic and chronic neuropathic pain. , 1994, Brain : a journal of neurology.
[13] A. Pertovaara,et al. Capsaicin-induced central facilitation of a nociceptive flexion reflex in humans , 1993, Neuroscience Letters.
[14] P. Pflimlin,et al. Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons. , 1993, European journal of pharmacology.
[15] W. Löscher,et al. Differences in anticonvulsant potency and adverse effects between dextromethorphan and dextrorphan in amygdala-kindled and non-kindled rats. , 1993, European journal of pharmacology.
[16] L. Arendt-Nielsen,et al. Are poor metabolisers of sparteine/debrisoquine less pain tolerant than extensive metabolisers? , 1993, Pain.
[17] L. Bertilsson,et al. Relationship between personality and debrisoquine hydroxylation capacity , 1993, Acta psychiatrica Scandinavica.
[18] M. Koltzenburg,et al. Dynamic and static components of mechanical hyperalgesia in human hairy skin , 1992, Pain.
[19] J. Jaffe,et al. Induction of phencyclidine-like behavior in rats by dextrorphan but not dextromethorphan , 1991, Pharmacology Biochemistry and Behavior.
[20] Clifford J. Woolf,et al. The induction and maintenance of central sensitization is dependent on N-methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states , 1991, Pain.
[21] J. Willer. Exploration clinique de la nociception par des techniques de réflexologie , 1990, Neurophysiologie Clinique/Clinical Neurophysiology.
[22] P. Bechtel,et al. Effect of quinidine on the dextromethorphan O-demethylase activity of microsomal fractions from human liver. , 1989, British journal of clinical pharmacology.
[23] P. Dayer,et al. Dextromethorphan O‐demethylation in liver microsomes as a prototype reaction to monitor cytochrome P‐450 db1 activity , 1989, Clinical pharmacology and therapeutics.
[24] H. Handwerker,et al. Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin , 1988, Brain Research.
[25] T. Leemann,et al. Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI). , 1988, Biochemical and biophysical research communications.
[26] D. Prince,et al. Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-d-aspartate in brain slices , 1988, Neuroscience Letters.
[27] D. Greenberg,et al. Dextromethorphan and dextrorphan as calcium channel antagonists , 1988, Brain Research.
[28] A. Dickenson,et al. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation. , 1987, Neuropharmacology.
[29] G. Cardinale,et al. Morphine and codeine are endogenous components of human cerebrospinal fluid. , 1987, Life sciences.
[30] J. Woodworth,et al. Bioavailability Evaluation of a Controlled‐Release Dextromethorphan Liquid , 1987, Journal of clinical pharmacology.
[31] Patrick D. Wall,et al. Dynamic receptive field plasticity in rat spinal cord dorsal horn following C-primary afferent input , 1987, Nature.
[32] P. Kenins. Responses of single nerve fibres to capsaicin applied to the skin , 1982, Neuroscience Letters.
[33] J. Willer,et al. Comparative study of perceived pain and nociceptive flexion reflex in man , 1977, Pain.
[34] P. Dayer,et al. Impact of environmental and genetic factors on codeine analgesia , 2004, European Journal of Clinical Pharmacology.
[35] T. Leemann,et al. Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers , 2004, European Journal of Clinical Pharmacology.
[36] P. Dayer,et al. Contribution of monoaminergic modulation to the analgesic effect of tramadol. , 1996, British journal of clinical pharmacology.
[37] J. Idänpään-Heikkilä,et al. WHO guidelines for good clinical practice (GCP) for trials on pharmaceutical products: responsibilities of the investigator. , 1994, Annals of medicine.
[38] P. Dayer,et al. Objective assessment of clonidine analgesia in man and influence of naloxone. , 1990, Life sciences.
[39] G. Pfaff,et al. Pharmacogenetics of dextromethorphan O-demethylation in man. , 1986, Xenobiotica; the fate of foreign compounds in biological systems.
[40] J. Besson,et al. [Peripheral and spinal mechanisms of nociception]. , 1986, Revue neurologique.