Synthesis and inhibiting activity of peptidylketones as substrate analogues of papain

[1]  F. Nome,et al.  The Use of 2,2,2-Trichloro-1-Arylethanones as Benzoylating Agents , 1987 .

[2]  S. Rosenberg,et al.  Novel renin inhibitors containing analogues of statine retro-inverted at the C-termini: specificity at the P2 histidine site. , 1987, Journal of medicinal chemistry.

[3]  R. Abeles,et al.  Reversible, slow, tight-binding inhibition of human leukocyte elastase. , 1987, Biochemical and biophysical research communications.

[4]  R. Stein,et al.  Mechanism of slow-binding inhibition of human leukocyte elastase by trifluoromethyl ketones. , 1987, Biochemistry.

[5]  T. Liang,et al.  Inhibition of papain by nitriles: mechanistic studies using NMR and kinetic measurements. , 1987, Archives of biochemistry and biophysics.

[6]  B. Imperiali,et al.  Inhibition of serine proteases by peptidyl fluoromethyl ketones. , 1986, Biochemistry.

[7]  P. Andrews,et al.  Carboxyl-modified amino acids and peptides as protease inhibitors. , 1986, Journal of medicinal chemistry.

[8]  B. Imperiali,et al.  A versatile synthesis of peptidyl fluoromethyl ketones , 1986 .

[9]  M. Gelb,et al.  Fluoro ketone inhibitors of hydrolytic enzymes. , 1985, Biochemistry.

[10]  D. Gorenstein,et al.  Carbon-13 NMR spectroscopy of "transition-state analog" complexes of N-acetyl-L-phenylalaninal and .alpha.-chymotrypsin , 1984 .

[11]  M. P. Gamcsik,et al.  Structure and stereochemistry of tetrahedral inhibitor complexes of papain by direct NMR observation , 1983 .

[12]  A. Frankfater,et al.  Mechanism of association of N-acetyl-L-phenylalanylglycinal to papain. , 1981, Biochemistry.

[13]  J. Morrison,et al.  [17] The kinetics of reversible tight-binding inhibition , 1979 .

[14]  S. Cha,et al.  Tight-binding inhibitors-I. Kinetic behavior. , 1975, Biochemical pharmacology.

[15]  K. Brocklehurst,et al.  Reactions of papain and of low-molecular-weight thiols with some aromatic disulphides. 2,2'-Dipyridyl disulphide as a convenient active-site titrant for papain even in the presence of other thiols. , 1973, The Biochemical journal.

[16]  R. Thompson.  Use of peptide aldehydes to generate transition-state analogs of elastase. , 1973, Biochemistry.

[17]  R. Wolfenden,et al.  Aldehydes as inhibitors of papain. , 1972, The Journal of biological chemistry.

[18]  H. Umezawa,et al.  Structures and Syntheses of Leupeptins Pr-LL and Ac-LL , 1969 .

[19]  B. Sweetman,et al.  Biologically oriented organic sulfur chemistry. I. Reactions of thiols with highly reactive carbonyl compounds , 1969 .

[20]  A. Berger,et al.  On the active site of proteases. 3. Mapping the active site of papain; specific peptide inhibitors of papain. , 1968, Biochemical and biophysical research communications.

[21]  J. Whitaker,et al.  Chemical modification of papain. I. Reaction with the chloromethyl ketones of phenylalanine and lysine and with phenylmethyl-sulfonyl fluoride. , 1968, Archives of biochemistry and biophysics.

[22]  G. Lienhard,et al.  Thiol Addition to the Carbonyl Group. Equilibria and Kinetics1 , 1966 .

[23]  J. Sharp,et al.  Trichloromethylation of Anhydrides. Ring—Chain Tautomerism1a , 1965 .

[24]  R. Lemieux,et al.  Notes - Osmium Tetroxide-Catalyzed Periodate Oxidation of Olefinic Bonds , 1956 .

[25]  D. J. Cook,et al.  The Preparation and Reactions of Some Fluorine-containing Nitro Compounds , 1954 .

[26]  H. Burkett,et al.  Trichloroaminoalcohols. I. 1,1,1-Trichloro-3-aminopropanol-2 and Derivatives , 1949 .

[27]  P. Levene,et al.  NOTE ON THE ACTION OF AMMONIA ON PROPYLENE OXIDE , 1927 .