With the increasing demand of floating structures in offshore, coastal and marine renewable energy engineering, the interaction between the mooring system and floating structure becomes more and more important. In this paper, motion responses of a semi-submersible platform with mooring system under regular wave conditions are investigated numerically by a viscous flow solver naoe-FOAM-SJTU based on the open source toolbox OpenFOAM. Influence of the mooring system on the platform motion responses is evaluated in two different ways. Investigations are covered for analysis methods adopted for solving mooring lines and the length of each part of a multi-component mooring line. Several important conclusions are drawn.Copyright © 2015 by ASME