Drp1 modulates mitochondrial stress responses to mitotic arrest

[1]  K. Khanna,et al.  Mitotic slippage: an old tale with a new twist , 2019, Cell cycle.

[2]  A. Villunger,et al.  Perturbing mitosis for anti‐cancer therapy: is cell death the only answer? , 2018, EMBO reports.

[3]  A. García-Sáez,et al.  Bax, Bak and beyond — mitochondrial performance in apoptosis , 2018, The FEBS journal.

[4]  B. Maček,et al.  WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy , 2017, Nature Communications.

[5]  Nolan W. Kennedy,et al.  The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species. , 2017, Developmental cell.

[6]  Anushya Muruganujan,et al.  PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements , 2016, Nucleic Acids Res..

[7]  M. Malumbres,et al.  Fueling the Cell Division Cycle. , 2017, Trends in cell biology.

[8]  R. Alvarez,et al.  Crosstalk between the mitochondrial fission protein, Drp1, and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients , 2016, Oncotarget.

[9]  W. Lederer,et al.  Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein , 2016, Molecular biology of the cell.

[10]  A. Musacchio The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics , 2015, Current Biology.

[11]  H. McBride,et al.  MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death. , 2015, Molecular cell.

[12]  M. Malumbres,et al.  AMPK and PFKFB3 mediate glycolysis and survival in response to mitophagy during mitotic arrest , 2015, Nature Cell Biology.

[13]  Stephen S. Taylor,et al.  MYC Is a Major Determinant of Mitotic Cell Fate , 2015, Cancer cell.

[14]  S. Geley,et al.  The NOXA–MCL1–BIM axis defines lifespan on extended mitotic arrest , 2015, Nature Communications.

[15]  Hongtao Yu,et al.  The complexity of life and death decisions in mitosis , 2014, Molecular & Cellular Oncology.

[16]  B. Weaver,et al.  How Taxol/paclitaxel kills cancer cells , 2014, Molecular biology of the cell.

[17]  Xian-Jin Xie,et al.  Genome‐wide siRNA screen reveals coupling between mitotic apoptosis and adaptation , 2014, The EMBO journal.

[18]  C. Streuli,et al.  Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest , 2014, Cell reports.

[19]  Stephen S. Taylor,et al.  Mitosis and apoptosis: how is the balance set? , 2013, Current opinion in cell biology.

[20]  S. Strack,et al.  Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules , 2013, The Journal of cell biology.

[21]  Simon C Watkins,et al.  Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress , 2012, Journal of Cell Science.

[22]  Stephen S. Taylor,et al.  The Spindle Assembly Checkpoint , 2012, Current Biology.

[23]  B. Maček,et al.  Global Detection of Protein Kinase D-dependent Phosphorylation Events in Nocodazole-treated Human Cells* , 2012, Molecular & Cellular Proteomics.

[24]  R. Salgia,et al.  Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  Atsushi Miyawaki,et al.  A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery. , 2011, Chemistry & biology.

[26]  P. Codogno,et al.  A new fluorescence-based assay for autophagy. , 2011, Chemistry & biology.

[27]  J. Pines,et al.  Cubism and the cell cycle: the many faces of the APC/C , 2011, Nature Reviews Molecular Cell Biology.

[28]  A. Cox,et al.  RalA and RalBP1 regulate mitochondrial fission at mitosis , 2011, Nature Cell Biology.

[29]  J. Lippincott-Schwartz,et al.  Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation , 2011, Proceedings of the National Academy of Sciences.

[30]  O. Ilkayeva,et al.  Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability , 2011, Molecular biology of the cell.

[31]  M. Mann,et al.  Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.

[32]  L. Scorrano,et al.  During autophagy mitochondria elongate, are spared from degradation and sustain cell viability , 2011, Nature Cell Biology.

[33]  R. Youle,et al.  Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin , 2010, The Journal of cell biology.

[34]  C. Dumontet,et al.  Microtubule-binding agents: a dynamic field of cancer therapeutics , 2010, Nature Reviews Drug Discovery.

[35]  R. Schwarzenbacher,et al.  Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization , 2010, Cell.

[36]  D. Rigden,et al.  Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation , 2010, Autophagy.

[37]  M. Pagano,et al.  The ubiquitin-specific protease USP47 is a novel β-TRCP interactor regulating cell survival , 2010, Oncogene.

[38]  Badrinath Roysam,et al.  A hyperfused mitochondrial state achieved at G1–S regulates cyclin E buildup and entry into S phase , 2009, Proceedings of the National Academy of Sciences.

[39]  W. Mckeehan,et al.  Robust autophagy/mitophagy persists during mitosis , 2009, Cell cycle.

[40]  H. McBride,et al.  Translocation of SenP5 from the Nucleoli to the Mitochondria Modulates DRP1-dependent Fission during Mitosis* , 2009, The Journal of Biological Chemistry.

[41]  M. Mann,et al.  MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.

[42]  J. Martinou,et al.  Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA , 2008, PloS one.

[43]  Stephen S. Taylor,et al.  Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. , 2008, Cancer cell.

[44]  T. Kuwana,et al.  Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. , 2008, Developmental cell.

[45]  Toshihiko Oka,et al.  Mitotic Phosphorylation of Dynamin-related GTPase Drp1 Participates in Mitochondrial Fission* , 2007, Journal of Biological Chemistry.

[46]  J. Estaquier,et al.  Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis , 2007, Cell Death and Differentiation.

[47]  Steven P Gygi,et al.  Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry , 2007, Nature Methods.

[48]  M. Mann,et al.  In-gel digestion for mass spectrometric characterization of proteins and proteomes , 2006, Nature Protocols.

[49]  M. Mann,et al.  Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips , 2007, Nature Protocols.

[50]  J. Martinou,et al.  Inhibiting the Mitochondrial Fission Machinery Does Not Prevent Bax/Bak-Dependent Apoptosis , 2006, Molecular and Cellular Biology.

[51]  Conly L. Rieder,et al.  Mitotic Checkpoint Slippage in Humans Occurs via Cyclin B Destruction in the Presence of an Active Checkpoint , 2006, Current Biology.

[52]  Geert J. P. L. Kops,et al.  On the road to cancer: aneuploidy and the mitotic checkpoint , 2005, Nature Reviews Cancer.

[53]  M. Priault,et al.  Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast , 2005, Cell Death and Differentiation.

[54]  S. Luo,et al.  Cdk5 Activator-binding Protein C53 Regulates Apoptosis Induced by Genotoxic Stress via Modulating the G2/M DNA Damage Checkpoint* , 2005, Journal of Biological Chemistry.

[55]  M. Jordan,et al.  Microtubules as a target for anticancer drugs , 2004, Nature Reviews Cancer.

[56]  S. Frank,et al.  Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis , 2002, The Journal of cell biology.

[57]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[58]  G. Chan,et al.  Human Bubr1 Is a Mitotic Checkpoint Kinase That Monitors Cenp-E Functions at Kinetochores and Binds the Cyclosome/APC , 1999, The Journal of cell biology.

[59]  Jean-Claude Martinou,et al.  Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis , 1999, The Journal of cell biology.

[60]  Junying Yuan,et al.  Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis , 1998, Cell.

[61]  M. De Brabander,et al.  The effects of methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl) carbamate, (R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro. , 1976, Cancer research.