Nociceptin effect on intestinal motility depends on opioid-receptor like-1 receptors and nitric oxide synthase co-localization.
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[1] J. Fichna,et al. Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum , 2013, Journal of peptide science : an official publication of the European Peptide Society.
[2] A. Janecka,et al. Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating κ‐opioid and cannabinoid receptors , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[3] R. Guerrini,et al. Central and peripheral role of the nociceptin/orphaninFQ system on normal and disturbed colonic motor function and faecal pellet output in the rat , 2008, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[4] B. Göke,et al. A NEW ELECTROPHYSIOLOGICAL TOOL TO INVESTIGATE THE SPATIAL NEURONAL PROJECTIONS WITHIN THE MYENTERIC ASCENDING REFLEX OF THE MOUSE COLON , 2008, Clinical and experimental pharmacology & physiology.
[5] D. Saur,et al. ORL-1 receptor mediates the action of nociceptin on ascending myenteric reflex pathways in rats. , 2007, Gastroenterology.
[6] G. Marsicano,et al. Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon. , 2004, American journal of physiology. Gastrointestinal and liver physiology.
[7] M. Storr,et al. Structural differences in the enteric neural network in murine colon: impact on electrophysiology. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[8] D. Saur,et al. Complex Regulation of Human Neuronal Nitric-oxide Synthase Exon 1c Gene Transcription , 2002, The Journal of Biological Chemistry.
[9] D. Saur,et al. Effects Of Endomorphin‐1 And ‐2 On μ‐Opioid Receptors In Myenteric Neurons And In The Peristaltic Reflex In Rat Small Intestine , 2002, Clinical and experimental pharmacology & physiology.
[10] G. Mawe,et al. Distribution and chemical coding of orphanin FQ/nociceptin‐immunoreactive neurons in the myenteric plexus of guinea pig intestines and sphincter of Oddi , 2001, The Journal of comparative neurology.
[11] M. Storr,et al. Effect of opioid active therapeutics on the ascending reflex pathway in the rat ileum , 2000, Neuropeptides.
[12] M. Osinski,et al. Orphanin FQ/nociceptin: a novel neuromodulator of gastrointestinal function? , 2000, Peptides.
[13] S. Salvadori,et al. Structure-activity relationships of nociceptin and related peptides: comparison with dynorphin A , 2000, Peptides.
[14] D. Saur,et al. Distinct expression of splice variants of neuronal nitric oxide synthase in the human gastrointestinal tract. , 2000, Gastroenterology.
[15] M. Storr,et al. Modulatory effect of endogenous and exogenous opioids on the excitatory reflex pathway of the rat ileum , 2000, Neuropeptides.
[16] S. Salvadori,et al. [Nphe(1)]nociceptin-(1-13)-NH(2) antagonizes nociceptin effects in the mouse colon. , 1999, European journal of pharmacology.
[17] J. Menzies,et al. In vitro agonist effects of nociceptin and [Phe(1)psi(CH(2)-NH)Gly(2)]nociceptin(1-13)NH(2) in the mouse and rat colon and the mouse vas deferens. , 1999, European journal of pharmacology.
[18] M. Murtaugh,et al. Cloning, expression and functional role of a nociceptin/orphanin FQ receptor in the porcine gastrointestinal tract. , 1999, European journal of pharmacology.
[19] P. Bass,et al. Peripheral and central actions of orphanin FQ (nociceptin) on murine colon. , 1999, The American journal of physiology.
[20] S. Watson,et al. Functional significance of a newly discovered neuropeptide, orphanin FQ, in rat gastrointestinal motility. , 1999, Gastroenterology.
[21] G. Pasternak,et al. Identification and differential regional expression of KOR‐3/ORL‐1 gene splice variants in mouse brain , 1998, FEBS letters.
[22] B. Hawes,et al. Nociceptin (ORL‐1) and μ‐Opioid Receptors Mediate Mitogen‐Activated Protein Kinase Activation in CHO Cells Through a Gi‐Coupled Signaling Pathway: Evidence for Distinct Mechanisms of Agonist‐Mediated Desensitization , 1998, Journal of neurochemistry.
[23] T. Yu,et al. Orphanin FQ/nociceptin inhibits synaptic transmission and long-term potentiation in rat dentate gyrus through postsynaptic mechanisms. , 1998, Journal of neurophysiology.
[24] D. Grandy,et al. Orphanin FQ has an inhibitory effect on the guinea pig ileum and the mouse vas deferens , 1997, Brain Research.
[25] S. Salvadori,et al. Pharmacological characterization of nociceptin receptor: an in vitro study. , 1997, Canadian journal of physiology and pharmacology.
[26] M. Christie,et al. Actions of the ORL1 Receptor Ligand Nociceptin on Membrane Properties of Rat Periaqueductal Gray Neurons In Vitro , 1997, The Journal of Neuroscience.
[27] F. Monsma,et al. Structure-Activity Relationship Studies on the Novel Neuropeptide Orphanin FQ* , 1996, The Journal of Biological Chemistry.
[28] D. Grandy,et al. Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor , 1995, Science.
[29] Marc Parmentier,et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor , 1995, Nature.
[30] I. Coupar,et al. The Peristaltic Reflex in the Rat Ileum: Evidence for Functional μ‐ and δ‐Opiate Receptors , 1995 .
[31] I. Coupar,et al. The peristaltic reflex in the rat ileum: evidence for functional mu- and delta-opiate receptors. , 1995, The Journal of pharmacy and pharmacology.
[32] C. Kozak,et al. Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family , 1994, FEBS letters.
[33] T. Miyata,et al. cDNA cloning and regional distribution of a novel member of the opioid receptor family , 1994, FEBS letters.
[34] E. Daniel,et al. Release of VIP and substance P from isolated perfused canine ileum. , 1989, The American journal of physiology.
[35] W. Kromer. The current status of opioid research on gastrointestinal motility. , 1989, Life sciences.
[36] B. Krevsky,et al. Role of opiate receptors in the regulation of colonic transit. , 1988, Gastroenterology.
[37] J. Grider,et al. Role of opioid neurons in the regulation of intestinal peristalsis. , 1987, The American journal of physiology.
[38] F. Lembeck,et al. Release of dynorphin, somatostatin and substance P from the vascularly perfused small intestine of the guinea‐pig during peristalsis , 1984, British journal of pharmacology.
[39] T. Smith,et al. The release of Met-enkephalin from the guinea-pig ileum at rest and during peristaltic activity. , 1983, Life sciences.
[40] T. Smith,et al. Peristalsis abolishes the release of methionine-enkephalin from guinea-pig ileum in vitro. , 1981, European journal of pharmacology.
[41] W. Kromer,et al. Opioids modulate periodicity rather than efficacy of peristaltic waves in the guinea pig ileum in vitro. , 1980, Life sciences.