Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study.

[1]  Xihong Lin,et al.  Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis , 2018, Intensive Care Medicine.

[2]  S. Alonso,et al.  Genomic Analyses of Human European Diversity at the Southwestern Edge: Isolation, African Influence and Disease Associations in the Canary Islands , 2018, Molecular biology and evolution.

[3]  S. Orfanos,et al.  Early increase of VEGF‐A is associated with resolution of ventilator‐associated pneumonia: Clinical and experimental evidence , 2018, Respirology.

[4]  M. Gonzalez-Garay,et al.  Genome‐Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor , 2018, American journal of respiratory and critical care medicine.

[5]  Klaus Ulrich Klein,et al.  Faculty of 1000 evaluation for Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. , 2018 .

[6]  David S. Wishart,et al.  DrugBank 5.0: a major update to the DrugBank database for 2018 , 2017, Nucleic Acids Res..

[7]  S. Karumanchi,et al.  Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis. , 2017, American journal of obstetrics and gynecology.

[8]  Diego di Bernardo,et al.  gene2drug: a Computational Tool for Pathway-based Rational Drug Repositioning , 2017, bioRxiv.

[9]  David T. Huang,et al.  Endothelial Permeability and Hemostasis in Septic Shock: Results From the ProCESS Trial , 2017, Chest.

[10]  D. Lawlor,et al.  Variants in the fetal genome near FLT1 are associated with risk of preeclampsia , 2017, Nature Genetics.

[11]  Jianying Guo,et al.  Monitoring of vascular endothelial growth factor and its soluble receptor levels in early trauma , 2017, The journal of trauma and acute care surgery.

[12]  William J. Astle,et al.  Allelic Landscape of Human Blood Cell Trait Variation and Links , 2016 .

[13]  M. Platzer,et al.  Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28 Day Mortality , 2016, EBioMedicine.

[14]  M. Kanai,et al.  Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set , 2016, Journal of Human Genetics.

[15]  D. Needham,et al.  Psychiatric Symptoms in Acute Respiratory Distress Syndrome Survivors: A 1-Year National Multicenter Study , 2016, Critical care medicine.

[16]  B. Guillen-Guio,et al.  Genetics of Acute Respiratory Distress Syndrome , 2016 .

[17]  M. Balaan,et al.  Acute Respiratory Distress Syndrome , 2016, Critical care nursing quarterly.

[18]  M. Pino-Yanes,et al.  Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene. , 2016, The Journal of allergy and clinical immunology.

[19]  R. Bellomo,et al.  The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). , 2016, JAMA.

[20]  Anders Larsson,et al.  Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. , 2016, JAMA.

[21]  Philip A. Ewels,et al.  Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C , 2015, Nature Genetics.

[22]  D. Grigoryev,et al.  Identification of Novel Single Nucleotide Polymorphisms Associated with Acute Respiratory Distress Syndrome by Exome-Seq , 2014, PloS one.

[23]  D. Talmor,et al.  Acute respiratory distress syndrome in the global context. , 2014, Global heart.

[24]  H. Collard,et al.  Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. , 2014, The New England journal of medicine.

[25]  A. Millar,et al.  Vascular Endothelial Growth Factor in Acute Lung Injury and Acute Respiratory Distress Syndrome , 2013, Respiration.

[26]  S. Jaber,et al.  Prone positioning in severe acute respiratory distress syndrome. , 2013, The New England journal of medicine.

[27]  W. Aird,et al.  Biomarkers of Endothelial Cell Activation in Early Sepsis , 2013, Shock.

[28]  J. Danesh,et al.  Large-scale association analysis identifies new risk loci for coronary artery disease , 2012, Nature Genetics.

[29]  Xifeng Wu,et al.  Variations in the vascular endothelial growth factor pathway predict pulmonary complications. , 2012, The Annals of thoracic surgery.

[30]  M. Rieder,et al.  Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. , 2012, American journal of human genetics.

[31]  Arthur S Slutsky,et al.  Acute Respiratory Distress Syndrome The Berlin Definition , 2012 .

[32]  H. Hakonarson,et al.  Genome Wide Association Identifies PPFIA1 as a Candidate Gene for Acute Lung Injury Risk Following Major Trauma , 2012, PloS one.

[33]  Stuart M Haslam,et al.  The Antifungal Drug Itraconazole Inhibits Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Glycosylation, Trafficking, and Signaling in Endothelial Cells* , 2011, The Journal of Biological Chemistry.

[34]  Robert M. Kacmarek,et al.  The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation , 2011, Intensive Care Medicine.

[35]  L. Ngo,et al.  The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis , 2010, Critical care.

[36]  D. Needham,et al.  Beyond mortality: future clinical research in acute lung injury. , 2010, American journal of respiratory and critical care medicine.

[37]  R. Crystal,et al.  VEGF levels in the alveolar compartment do not distinguish between ARDS and hydrostatic pulmonary oedema , 2005, European Respiratory Journal.

[38]  H. Dvorak,et al.  VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. , 2003, Trends in cardiovascular medicine.

[39]  A. Verin,et al.  Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells. , 2001, American journal of physiology. Lung cellular and molecular physiology.

[40]  D. Schoenfeld,et al.  Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. , 2000, The New England journal of medicine.

[41]  M. Lamy,et al.  The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. , 1994, American journal of respiratory and critical care medicine.

[42]  R. Kendall,et al.  Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.