The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation.
暂无分享,去创建一个
J. Bousquet | T. Casale | S. Holgate | S. Wenzel | Y. Deniz | C. Reisner | J. Bousquet | Y. Deniz
[1] Stephen T Holgate,et al. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. , 2004, American journal of respiratory and critical care medicine.
[2] A. Togias,et al. Omalizumab-induced reductions in mast cell FcεRI expression and function , 2004 .
[3] E. Chilvers,et al. Efficacy and tolerability of anti‐immunoglobulin E therapy with omalizumab in patients with poorly controlled (moderate‐to‐severe) allergic asthma , 2004, Allergy.
[4] L. Boulet,et al. Efficacy and tolerability of anti‐immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR , 2004, Allergy.
[5] J. Bousquet,et al. Efficacy and safety of a recombinant anti‐immunoglobulin E antibody (omalizumab) in severe allergic asthma , 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[6] J. Bousquet,et al. Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma. , 2004, Chest.
[7] T. Casale,et al. Omalizumab rapidly decreases nasal allergic response and FcεRI on basophils , 2004 .
[8] T. Casale,et al. Omalizumab treatment downregulates dendritic cell FcεRI expression , 2003 .
[9] D. Metcalfe,et al. Human dendritic cell 1 and dendritic cell 2 subsets express FcepsilonRI: correlation with serum IgE and allergic asthma. , 2003, The Journal of allergy and clinical immunology.
[10] Toshiaki Kawakami,et al. Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcεRI , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[11] C. Jackson,et al. Allergen sensitization and bronchial hyper‐responsiveness to adenosine monophosphate in asthmatic patients , 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[12] D. Postma,et al. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma , 2003, European Respiratory Journal.
[13] T. Casale,et al. Omalizumab, an anti-IgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis. , 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
[14] O. Noga,et al. Immunological and Clinical Changes in Allergic Asthmatics following Treatment with Omalizumab , 2003, International Archives of Allergy and Immunology.
[15] U. Wahn,et al. Treatment with omalizumab normalizes the number of myeloid dendritic cells during the grass pollen season. , 2003, The Journal of allergy and clinical immunology.
[16] T. Casale,et al. Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma. , 2003, The Journal of allergy and clinical immunology.
[17] Toshiaki Kawakami,et al. Regulation of mast-cell and basophil function and survival by IgE , 2002, Nature Reviews Immunology.
[18] T. Sandström,et al. The effect of omalizumab on nasal allergic inflammation. , 2002, The Journal of allergy and clinical immunology.
[19] D. Botstein,et al. Transcriptional response of human mast cells stimulated via the FcεRI and identification of mast cells as a source of IL-11 , 2002, BMC Immunology.
[20] T. Casale,et al. Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial. , 2001, JAMA.
[21] W. Busse,et al. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma. , 2001, The Journal of allergy and clinical immunology.
[22] R. Townley,et al. The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics. , 2001, The European respiratory journal.
[23] H. Milgrom,et al. Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab). , 2001, Pediatrics.
[24] A. B. Kay,et al. Allergy and Allergic Diseases , 2001 .
[25] A B Kay,et al. Allergy and allergic diseases. Second of two parts. , 2001, The New England journal of medicine.
[26] A B Kay,et al. Allergy and allergic diseases. First of two parts. , 2001, The New England journal of medicine.
[27] J. Bousquet,et al. Efficacy of Omalizumab, an Anti-immunoglobulin E Antibody, in Patients with Allergic Asthma at High Risk of Serious Asthma-related Morbidity and Mortality* , 2001, Current medical research and opinion.
[28] T. Haahtela,et al. Recombinant humanized mAb-E25, an anti-IgE mAb, in birch pollen-induced seasonal allergic rhinitis. , 2000, The Journal of allergy and clinical immunology.
[29] S. Galli,et al. The diverse potential effector and immunoregulatory roles of mast cells in allergic disease. , 2000, The Journal of allergy and clinical immunology.
[30] P. Sly,et al. The role of allergy in the development of asthma , 1999, Nature.
[31] L. Lichtenstein,et al. Upregulation of FcϵRI on human basophils by IgE antibody is mediated by interaction of IgE with FcϵRI , 1999 .
[32] L. Boulet,et al. Inhibitory effects of an anti-IgE antibody E25 on allergen-induced early asthmatic response. , 1997, American journal of respiratory and critical care medicine.
[33] H. Boushey,et al. The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects. , 1997, American journal of respiratory and critical care medicine.
[34] A. Togias,et al. Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. , 1997, Journal of immunology.
[35] A. Togias,et al. Serum IgE level drives basophil and mast cell IgE receptor display. , 1997, International archives of allergy and immunology.
[36] R. Martin,et al. Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma , 1995, The Journal of experimental medicine.
[37] F. Martinez,et al. Association of asthma with serum IgE levels and skin-test reactivity to allergens. , 1989, The New England journal of medicine.