Alzheimer’s disease cortical morphological phenotypes are associated with TOMM40′523-APOE haplotypes

[1]  A. Kulminski,et al.  Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers , 2022, Aging.

[2]  W. Lieb,et al.  Long-Lived Individuals Show a Lower Burden of Variants Predisposing to Age-Related Diseases and a Higher Polygenic Longevity Score , 2022, International journal of molecular sciences.

[3]  Sterling C. Johnson,et al.  Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan. , 2022, Brain : a journal of neurology.

[4]  Maria-Eleni Dounavi,et al.  Fractal dimension of the brain in neurodegenerative disease and dementia: A systematic review , 2022, Ageing Research Reviews.

[5]  A. Saykin,et al.  Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains , 2022, BMC Medical Genomics.

[6]  H. Arboleda,et al.  Genetic Variants and Haplotypes of TOMM40, APOE, and APOC1 are Related to the Age of Onset of Late-onset Alzheimer Disease in a Colombian Population , 2022, Alzheimer disease and associated disorders.

[7]  A. Saykin,et al.  Integrative analysis of eQTL and GWAS summary statistics reveals novel genes related to Alzheimer's disease , 2021, Alzheimer's & Dementia.

[8]  A. Kulminski,et al.  Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk , 2021, Neurobiology of Aging.

[9]  F. Mastaglia,et al.  TOMM40‘523’ poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson’s disease , 2021, NPJ Parkinson's disease.

[10]  Fractal Dimension , 2020, Modern Classical Mechanics.

[11]  M. Giannelli,et al.  Toward a more reliable characterization of fractal properties of the cerebral cortex of healthy subjects during the lifespan , 2020, Scientific Reports.

[12]  D. Cook,et al.  Collective effects of age, sex, genotype, and cognitive status on fitness outcomes , 2020, Alzheimer's & dementia.

[13]  Hua-jun Chen,et al.  Brain Cortical Complexity Alteration in Amyotrophic Lateral Sclerosis: A Preliminary Fractal Dimensionality Study , 2020, BioMed research international.

[14]  P. Sachdev,et al.  Differential longitudinal changes in structural complexity and volumetric measures in community-dwelling older individuals , 2020, Neurobiology of Aging.

[15]  J. Lambert,et al.  Genetics of Alzheimer’s disease: where we are, and where we are going , 2019, Current Opinion in Neurobiology.

[16]  J. O'Brien,et al.  Cortical Complexity Analyses and Their Cognitive Correlate in Alzheimer’s Disease and Frontotemporal Dementia , 2019, Journal of Alzheimer's disease : JAD.

[17]  R. Swerdlow,et al.  TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE ɛ3 Homozygotes. , 2019, Journal of Alzheimer's disease : JAD.

[18]  Nick C Fox,et al.  Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing , 2019, Nature Genetics.

[19]  C. E. Han,et al.  Comparison of neurodegenerative types using different brain MRI analysis metrics in older adults with normal cognition, mild cognitive impairment, and Alzheimer’s dementia , 2019, PloS one.

[20]  G. Bu,et al.  Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies , 2019, Nature Reviews Neurology.

[21]  Paul A. Harris,et al.  The REDCap consortium: Building an international community of software platform partners , 2019, J. Biomed. Informatics.

[22]  G. Small,et al.  Longer TOMM40 poly-T variants associated with higher FDDNP-PET medial temporal tau and amyloid binding , 2018, PloS one.

[23]  J. Whitwell,et al.  Alzheimer's disease neuroimaging , 2018, Current opinion in neurology.

[24]  O. Chiba-Falek,et al.  The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes , 2018, Alzheimer's & Dementia.

[25]  R. Marioni,et al.  GWAS on family history of Alzheimer’s disease , 2018, bioRxiv.

[26]  S. Yano,et al.  Differential Effects of the Factor Structure of the Wechsler Memory Scale-Revised on the Cortical Thickness and Complexity of Patients Aged Over 75 Years in a Memory Clinic Setting , 2017, Front. Aging Neurosci..

[27]  D. Bennett,et al.  Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline , 2017, Alzheimer's & Dementia.

[28]  Sterling C. Johnson,et al.  Family history and TOMM40 ‘523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts , 2017, Alzheimer's & Dementia.

[29]  Jorge Sepulcre,et al.  Complexity analysis of cortical surface detects changes in future Alzheimer's disease converters , 2017, Human brain mapping.

[30]  A. Roses,et al.  APOE ε4-TOMM40 ‘523 haplotypes and the risk of Alzheimer’s disease in older Caucasian and African Americans , 2017, PloS one.

[31]  Theresa M. Harrison,et al.  Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant , 2017, Alzheimer's & Dementia.

[32]  R. Swerdlow,et al.  Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients , 2017, Redox biology.

[33]  M. Mallar Chakravarty,et al.  Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients , 2017, Frontiers in aging neuroscience.

[34]  Jonathan D Mahnken,et al.  Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial , 2017, PloS one.

[35]  Christopher R. Madan,et al.  Cortical complexity as a measure of age-related brain atrophy , 2016, NeuroImage.

[36]  J. Quinn,et al.  A TOMM40 poly-T variant modulates gene expression and is associated with vocabulary ability and decline in nonpathologic aging , 2016, Neurobiology of Aging.

[37]  I. Deary,et al.  APOE/TOMM 40 genetic loci, white matter hyperintensities, and cerebral microbleeds , 2015, International journal of stroke : official journal of the International Stroke Society.

[38]  J. Donnelly,et al.  Dose-Response of Aerobic Exercise on Cognition: A Community-Based, Pilot Randomized Controlled Trial , 2015, PloS one.

[39]  I. Deary,et al.  Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity? , 2014, Translational Psychiatry.

[40]  A. Roses,et al.  The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes , 2014, European Neuropsychopharmacology.

[41]  Joanna M. Wardlaw,et al.  Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936 , 2014, Neurobiology of Aging.

[42]  I. Deary,et al.  Alzheimer’s Disease Susceptibility Genes APOE and TOMM40, and Hippocampal Volumes in the Lothian Birth Cohort 1936 , 2013, PloS one.

[43]  Mark T. W. Ebbert,et al.  Genetics of Alzheimer's Disease , 2013, BioMed Research International.

[44]  G. Alexander,et al.  Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. , 2013, JAMA neurology.

[45]  Jong-Min Lee,et al.  Automated Sulcal Depth Measurement on Cortical Surface Reflecting Geometrical Properties of Sulci , 2013, PloS one.

[46]  Christian Gaser,et al.  Cortical thickness and central surface estimation , 2013, NeuroImage.

[47]  A. Roses,et al.  Longitudinal modeling of cognitive aging and the TOMM40 effect , 2012, Alzheimer's & Dementia.

[48]  J. Donnelly,et al.  A community-based approach to trials of aerobic exercise in aging and Alzheimer's disease. , 2012, Contemporary clinical trials.

[49]  Paul K Crane,et al.  Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. , 2012, Archives of neurology.

[50]  A. Roses,et al.  A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging , 2012, Alzheimer's & Dementia.

[51]  Michael W. Lutz,et al.  Levels of cerebrospinal fluid neurofilament light protein in healthy elderly vary as a function of TOMM40 variants , 2012, Experimental Gerontology.

[52]  W. Kukull,et al.  Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010 , 2012, Journal of neuropathology and experimental neurology.

[53]  J. Nierenberg,et al.  Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants , 2012, Psychoneuroendocrinology.

[54]  D. Balota,et al.  Role of family history for Alzheimer biomarker abnormalities in the adult children study. , 2011, Archives of neurology.

[55]  R. Swerdlow,et al.  Alzheimer’s Disease Pathologic Cascades: Who Comes First, What Drives What , 2011, Neurotoxicity Research.

[56]  David M Holtzman,et al.  Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease. , 2011, Archives of neurology.

[57]  Robert C. Green,et al.  The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ɛ3/ɛ3 genotype , 2011, Alzheimer's & Dementia.

[58]  Paul M. Thompson,et al.  Local cortical surface complexity maps from spherical harmonic reconstructions , 2011, NeuroImage.

[59]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[60]  P. Thompson,et al.  Algorithms to Improve the Reparameterization of Spherical Mappings of Brain Surface Meshes , 2011, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

[61]  Brandon Brown,et al.  Fractal dimension analysis of the cortical ribbon in mild Alzheimer's disease , 2010, NeuroImage.

[62]  A. Roses,et al.  Genetic variation at a single locus and age of onset for Alzheimer's disease , 2010, Alzheimer's & Dementia.

[63]  R. Honea,et al.  Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease , 2010, Neurology.

[64]  A D Roses,et al.  A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease , 2009, The Pharmacogenomics Journal.

[65]  Amity E. Green,et al.  Automated 3D mapping of hippocampal atrophy and its clinical correlates in 400 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls , 2009, Human brain mapping.

[66]  Russell H. Swerdlow,et al.  The Alzheimer's disease mitochondrial cascade hypothesis: An update , 2009, Experimental Neurology.

[67]  P. Harris,et al.  Research electronic data capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support , 2009, J. Biomed. Informatics.

[68]  Nathaniel Mercaldo,et al.  The Alzheimer's Disease Centers' Uniform Data Set (UDS): The Neuropsychologic Test Battery , 2009, Alzheimer disease and associated disorders.

[69]  Norbert Schuff,et al.  Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls , 2009, NeuroImage.

[70]  Sang Won Seo,et al.  Sulcal morphology changes and their relationship with cortical thickness and gyral white matter volume in mild cognitive impairment and Alzheimer's disease , 2008, NeuroImage.

[71]  John Ashburner,et al.  A fast diffeomorphic image registration algorithm , 2007, NeuroImage.

[72]  Rebecca F. Halperin,et al.  A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. , 2007, The Journal of clinical psychiatry.

[73]  N. Schuff,et al.  Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia. , 2006, Brain : a journal of neurology.

[74]  Anders M. Dale,et al.  An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest , 2006, NeuroImage.

[75]  J Ashburner,et al.  Computational neuroanatomy: new perspectives for neuroradiology. , 2001, Revue neurologique.

[76]  J. Morris.  The Clinical Dementia Rating (CDR) , 1993, Neurology.

[77]  Jacob Cohen.  A Coefficient of Agreement for Nominal Scales , 1960 .

[78]  D. Selkoe.  Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.

[79]  Vladimir V. Frolkis,et al.  Neurobiology of Aging , 2019, Psychobiology of Behaviour.

[80]  R. Swerdlow,et al.  A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease. , 2004, Medical hypotheses.