Modulation of inhibitory synapses in the mammalian brain

Recent studies have identified new forms of short-term and long-term modulation at inhibitory synapses. In cerebellum and hippocampus, a transient inhibition of synaptic efficacy has been found to involve a Ca(2+)-dependent retrograde messenger. Exciting results from work in the visual cortex suggest that forms of both long-term potentiation and long-term depression occur in cortical inhibitory synapses.

[1]  H. Gerschenfeld,et al.  Beta‐adrenergic enhancement of inhibitory synaptic activity in rat cerebellar stellate and Purkinje cells. , 1993, The Journal of physiology.

[2]  D. Madison,et al.  Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons , 1992, Neuron.

[3]  J. Behrends,et al.  Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: excitation of GABAergic interneurons and inhibition of GABA-release. , 1993, Journal of neurophysiology.

[4]  C. Armstrong,et al.  Inhibitory synaptic currents in rat cerebellar Purkinje cells: modulation by postsynaptic depolarization. , 1992, The Journal of physiology.

[5]  W. A. Wilson,et al.  GABAB autoreceptors mediate activity-dependent disinhibition and enhance signal transmission in the dentate gyrus. , 1993, Journal of neurophysiology.

[6]  Hideto Kaba,et al.  INDUCTION OF AN OLFACTORY MEMORY BY THE ACTIVATION OF A METABOTROPIC GLUTAMATE RECEPTOR , 1994 .

[7]  A. Konnerth,et al.  Potentiation of GABA-mediated currents by cAMP-dependent protein kinase. , 1992, Neuroreport.

[8]  J. Burke,et al.  Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[9]  T. Otis.  Lasting potentiation of inhibition is associated with an increased number of GABA_A receptors activated during miniature inhibitory postsynaptic currents , 1994 .

[10]  A. Marty,et al.  Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents , 1991, Neuron.

[11]  B H Gähwiler,et al.  Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro. , 1989, Journal of neurophysiology.

[12]  B. Alger,et al.  Postsynaptic spike firing reduces synaptic GABAA responses in hippocampal pyramidal cells , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[13]  B. Gähwiler,et al.  Comparison of the actions of adenosine at pre‐ and postsynaptic receptors in the rat hippocampus in vitro. , 1992, The Journal of physiology.

[14]  W. A. Wilson,et al.  Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons , 1993, Neuron.

[15]  N. Slater,et al.  Activation of NMDA receptors blocks GABAergic inhibition in an in vitro model of epilepsy , 1987, Nature.

[16]  R. Wong,et al.  Suppression of GABAA receptor responses by NMDA application in hippocampal neurones acutely isolated from the adult guinea‐pig. , 1995, The Journal of physiology.

[17]  J. Rekling,et al.  Effects of met-enkephalin on GABAergic spontaneous miniature IPSPs in organotypic slice cultures of the rat hippocampus , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[18]  B. Gähwiler,et al.  Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus , 1992, Neuron.

[19]  H. Korn,et al.  Serotonergic facilitation of quantal release at central inhibitory synapses , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[20]  A. Marty,et al.  Neighboring cerebellar purkinje cells communicate via retrograde inhibition of common presynaptic interneurons , 1993, Neuron.

[21]  Y. Komatsu,et al.  Age-dependent long-term potentiation of inhibitory synaptic transmission in rat visual cortex , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[22]  S. Nakanishi,et al.  Role of a metabotropic glutamate receptor in synaptic modulation in the accessory olfactory bulb , 1993, Nature.

[23]  S. Thompson,et al.  Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitro , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[24]  I. Módy,et al.  Differential activation of GABAA and GABAB receptors by spontaneously released transmitter. , 1992, Journal of neurophysiology.

[25]  M. Scanziani,et al.  Presynaptic inhibition in the hippocampus , 1993, Trends in Neurosciences.

[26]  A. Konnerth,et al.  Synaptic excitation produces a long-lasting rebound potentiation of inhibitory synaptic signals in cerebellar Purkinje cells , 1992, Nature.

[27]  D. Faber,et al.  Long-term potentiation of inhibitory circuits and synapses in the central nervous system. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[28]  R. Miles,et al.  Metabotropic glutamate receptors mediate a post‐tetanic excitation of guinea‐pig hippocampal inhibitory neurones. , 1993, The Journal of physiology.

[29]  Y. Komatsu,et al.  Long-term modification of inhibitory synaptic transmission in developing visual cortex. , 1993, Neuroreport.

[30]  B H Gähwiler,et al.  Mechanism of mu‐opioid receptor‐mediated presynaptic inhibition in the rat hippocampus in vitro. , 1993, The Journal of physiology.

[31]  B. Alger,et al.  Depolarization-induced suppression of GABAergic inhibition in rat hippocampal pyramidal cells: G protein involvement in a presynaptic mechanism , 1994, Neuron.

[32]  J. Disterhoft,et al.  Activation of metabotropic glutamate receptors induces long-term depression of GABAergic inhibition in hippocampus. , 1993, Journal of neurophysiology.

[33]  P. Calabresi,et al.  Activation of metabotropic glutamate receptors inhibits calcium currents and GABA-mediated synaptic potentials in striatal neurons , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[34]  T. A. Pitler,et al.  Cholinergic excitation of GABAergic interneurons in the rat hippocampal slice. , 1992, The Journal of physiology.

[35]  I. Módy,et al.  Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[36]  S N Davies,et al.  Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus. , 1990, The Journal of physiology.

[37]  R. Miles,et al.  Dual modulation of synaptic inhibition by distinct metabotropic glutamate receptors in the rat hippocampus. , 1995, The Journal of physiology.

[38]  S. Thompson.  Modulation of inhibitory synaptic transmission in the hippocampus , 1994, Progress in Neurobiology.

[39]  A. Marty,et al.  Presynaptic metabotropic glutamatergic regulation of inhibitory synapses in rat cerebellar slices. , 1995, The Journal of physiology.