The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity.

[1]  Nisha S. Sipes,et al.  Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers? , 2019, Environmental science & technology letters.

[2]  Manhoi Hur,et al.  mRNA-Sequencing Identifies Liver as a Potential Target Organ for Triphenyl Phosphate in Embryonic Zebrafish. , 2019, Toxicological sciences : an official journal of the Society of Toxicology.

[3]  H. Stapleton,et al.  Diphenyl Phosphate-Induced Toxicity During Embryonic Development. , 2019, Environmental science & technology.

[4]  Robert L. Tanguay,et al.  Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis. , 2019, Computational toxicology.

[5]  Nisha S. Sipes,et al.  Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance. , 2018, Neurotoxicology and teratology.

[6]  Yongyong Guo,et al.  Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae. , 2018, Aquatic toxicology.

[7]  Skylar W. Marvel,et al.  ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models , 2018, BMC Bioinformatics.

[8]  E. Levin,et al.  Developmental exposure to low concentrations of two brominated flame retardants, BDE‐47 and BDE‐99, causes life‐long behavioral alterations in zebrafish , 2017, Neurotoxicology.

[9]  Alice Krebs,et al.  Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library , 2017, Archives of Toxicology.

[10]  Lisa Truong,et al.  A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish , 2017, PloS one.

[11]  Lisa Truong,et al.  Optimizing multi-dimensional high throughput screening using zebrafish. , 2016, Reproductive toxicology.

[12]  Marjolein V. Smith,et al.  Editor's Highlight: Comparative Toxicity of Organophosphate Flame Retardants and Polybrominated Diphenyl Ethers to Caenorhabditis elegans. , 2016, Toxicological sciences : an official journal of the Society of Toxicology.

[13]  P. Lee Ferguson,et al.  Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards , 2016, Environmental science & technology.

[14]  Yan Jiang,et al.  Crosstalk between AhR and wnt/β-catenin signal pathways in the cardiac developmental toxicity of PM2.5 in zebrafish embryos. , 2016, Toxicology.

[15]  Windy A. Boyd,et al.  Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. , 2015, Neurotoxicology and teratology.

[16]  E. Levin,et al.  Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior. , 2015, Neurotoxicology and teratology.

[17]  K. Jarema,et al.  Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish. , 2015, Neurotoxicology and teratology.

[18]  Skylar W. Marvel,et al.  High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes , 2015, Archives of Toxicology.

[19]  Robert L. Tanguay,et al.  Advanced morphological - behavioral test platform reveals neurodevelopmental defects in embryonic zebrafish exposed to comprehensive suite of halogenated and organophosphate flame retardants. , 2015, Toxicological sciences : an official journal of the Society of Toxicology.

[20]  H. Stapleton,et al.  Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. , 2014, Environmental science & technology.

[21]  Robert L. Tanguay,et al.  A rapid throughput approach identifies cognitive deficits in adult zebrafish from developmental exposure to polybrominated flame retardants. , 2014, Neurotoxicology.

[22]  Robert Gerlai,et al.  Zebrafish as an emerging model for studying complex brain disorders. , 2014, Trends in pharmacological sciences.

[23]  R. Westerink,et al.  A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: prioritization in search for safe(r) alternatives , 2014, Archives of Toxicology.

[24]  H. Stapleton,et al.  Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.

[25]  Anton J. Enright,et al.  The zebrafish reference genome sequence and its relationship to the human genome , 2013, Nature.

[26]  David Dix,et al.  A Computational Model Predicting Disruption of Blood Vessel Development , 2013, PLoS Comput. Biol..

[27]  Liang-Hong Guo,et al.  Molecular toxicology of polybrominated diphenyl ethers: nuclear hormone receptor mediated pathways. , 2013, Environmental science. Processes & impacts.

[28]  Stephan C F Neuhauss,et al.  Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond. , 2013, Zebrafish.

[29]  Jiangfei Chen,et al.  Developmental lead acetate exposure induces embryonic toxicity and memory deficit in adult zebrafish. , 2012, Neurotoxicology and teratology.

[30]  H. Stapleton,et al.  Early Zebrafish Embryogenesis Is Susceptible to Developmental TDCPP Exposure , 2012, Environmental health perspectives.

[31]  S. Kennedy,et al.  Effects of tris(1,3-dichloro-2-propyl) phosphate and tris(1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal cells. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.

[32]  Mushfiqur R. Sarker,et al.  Automated Zebrafish Chorion Removal and Single Embryo Placement , 2012, Journal of laboratory automation.

[33]  S. Haddad,et al.  In vitro neurotoxicity data in human risk assessment of polybrominated diphenyl ethers (PBDEs): overview and perspectives. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.

[34]  David M. Reif,et al.  Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data , 2010, Environmental health perspectives.

[35]  John D. Meeker,et al.  House Dust Concentrations of Organophosphate Flame Retardants in Relation to Hormone Levels and Semen Quality Parameters , 2009, Environmental health perspectives.

[36]  Max Kuhn,et al.  Building Predictive Models in R Using the caret Package , 2008 .

[37]  Wout Slob,et al.  A Comparison of Three Methods for Calculating Confidence Intervals for the Benchmark Dose , 2004, Risk analysis : an official publication of the Society for Risk Analysis.

[38]  Jortner Bs,et al.  Organophosphate-induced delayed neurotoxicity of triarylphosphates. , 1999 .

[39]  C. Kimmel,et al.  Stages of embryonic development of the zebrafish , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[40]  D. Barceló,et al.  Determination of Organophosphorus Compounds in Mediterranean Coastal Waters and Biota Samples Using Gas Chromatography with Nitrogen-Phosphorus and Chemical Ionization Mass Spectrometric Detection , 1990 .

[41]  J. Tukey,et al.  Variations of Box Plots , 1978 .

[42]  Lisa Truong,et al.  Evaluation of Embryotoxicity Using the Zebrafish Model. , 2017, Methods in molecular biology.

[43]  J. de Boer,et al.  Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis. , 2012, Chemosphere.

[44]  B. Jortner,et al.  Organophosphate-induced delayed neurotoxicity of triarylphosphates. , 1999, Neurotoxicology.