The use of near-infrared light for safe and effective visualization of subsurface blood vessels to facilitate blood withdrawal in children.

Obtaining access to blood vessels can be difficult, especially in children. Visualization of subsurface blood vessels might be a solution. Ultrasound and visible light have been used to this purpose, but have some drawbacks. Near-infrared light might be a better option since subsurface blood vessels can be visualized in high contrast due to less absorption and scattering in tissue as compared to visible light. Our findings with a multispectral imaging system support this theory. A device, the VascuLuminator, was developed, based on transillumination of the puncture site with near-infrared light. The VascuLuminator was designed to meet the requirements of compact and safe use. A phantom study showed that the maximum depth of visibility (5.5mm for a 3.6mm blood vessel) is sufficient to visualize blood vessels in typical locations for peripheral venous and arterial access. A quantitative comparison of the VascuLuminator and to two other vessel imaging devices, using reflection of near-infrared light instead of transillumination, was conducted. The VascuLuminator is able to decrease failure at first attempt in blood withdrawal in pediatric patients from 10/80 (13%) to 1/45 (2%; P=.05).

[1]  F. Mastik,et al.  Remote Non-invasive Stereoscopic Imaging of Blood Vessels: First In-vivo Results of a New Multispectral Contrast Enhancement Technology , 2006, Annals of Biomedical Engineering.

[2]  M. V. van Gemert,et al.  Light dosimetry in optical phantoms and in tissues: I. Multiple flux and transport theory. , 1988, Physics in medicine and biology.

[3]  W. Zempsky,et al.  Optimizing the Management of Peripheral Venous Access Pain in Children: Evidence, Impact, and Implementation , 2008, Pediatrics.

[4]  Holly A Hess A biomedical device to improve pediatric vascular access success. , 2010, Pediatric Nursing.

[5]  P. Ishimine,et al.  Randomized Controlled Trial of Ultrasound-Guided Peripheral Intravenous Catheter Placement Versus Traditional Techniques in Difficult-Access Pediatric Patients , 2009, Pediatric emergency care.

[6]  Jeremy C. Hebden,et al.  Determination of the transport scattering coefficient of red blood cells , 1999, Photonics West - Biomedical Optics.

[7]  H. Zeman,et al.  Vein Imaging: A New Method of Near Infrared Imaging, Where a Processed Image Is Projected onto the Skin for the Enhancement of Vein Treatment , 2006, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[8]  Herke Jan Noordmans,et al.  Feasibility of multi-spectral imaging system to provide enhanced demarcation for skin tumor resection , 2007, SPIE BiOS.

[9]  B. Pogue,et al.  Tutorial on diffuse light transport. , 2008, Journal of biomedical optics.

[10]  H. J. van Staveren,et al.  Light scattering in Intralipid-10% in the wavelength range of 400-1100 nm. , 1991, Applied optics.

[11]  Deborah C. Hsu,et al.  Efficacy of a Near-Infrared Light Device in Pediatric Intravenous Cannulation: A Randomized Controlled Trial , 2011, Pediatric emergency care.

[12]  G. Williams,et al.  Cold light, heat burn. , 2000, Burns : journal of the International Society for Burn Injuries.

[13]  D T Delpy,et al.  A phantom for the testing and calibration of near infra-red spectrometers. , 1994, Physics in medicine and biology.

[14]  V. Zharov,et al.  Infrared imaging of subcutaneous veins , 2004, Lasers in surgery and medicine.

[15]  K. Yen,et al.  Derivation of the DIVA Score: A Clinical Prediction Rule for the Identification of Children With Difficult Intravenous Access , 2008, Pediatric emergency care.

[16]  F. Jöbsis Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. , 1977, Science.

[17]  A. N. Bashkatov,et al.  Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm , 2005 .

[18]  Ontikova Nm,et al.  Increase in the information content of the image of the surface veins by using a television infrascope , 1976 .

[19]  A. Roggan,et al.  Optical Properties of Circulating Human Blood in the Wavelength Range 400-2500 nm. , 1999, Journal of biomedical optics.

[20]  B. Becker,et al.  VeinViewer-assisted Intravenous catheter placement in a pediatric emergency department. , 2011, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[21]  J. Kuint,et al.  Transillumination of the palm for venipuncture in infants , 2001, Pediatric emergency care.

[22]  M. Kohl,et al.  Near-infrared optical properties of ex vivo human skin and subcutaneous tissues measured using the Monte Carlo inversion technique. , 1998, Physics in medicine and biology.

[23]  Max A Viergever,et al.  Visualizing Veins With Near-Infrared Light to Facilitate Blood Withdrawal in Children , 2011, Clinical pediatrics.

[24]  Shin-ichiro Umemura,et al.  Near-infrared finger vein patterns for personal identification. , 2002, Applied optics.