Bilateral electrical stimulation of a congenitally-deaf ear and of an acquired-deaf ear.

Two identical multichannel intracochlear prostheses were implanted in the same patient. The first prosthesis, implanted in the congenitally-deaf right ear, elicited clear sound perception but no speech recognition. After 2 years, a second prosthesis, implanted in the acquired-deaf left ear, enabled the patient to understand speech without lip-reading. Brainstem and middle-latency evoked potentials were similar with electrical stimulation of both ears and resembled those evoked by acoustic stimuli in subjects with normal hearing. Cortical electric and magnetic responses differed for right- and left-sided electrical stimulation suggesting that stimulation of the congenitally-deaf ear elicited an abnormal activation of the auditory cortex. These results suggest that only cortical responses were affected by the different histories of deafness of the ears.

[1]  D. Moore.  Postnatal development of the mammalian central auditory system and the neural consequences of auditory deprivation. , 1985, Acta oto-laryngologica. Supplementum.

[2]  J. Mäkelä,et al.  Activation of the auditory cortex by cochlear stimulation in a deaf patient , 1986, Neuroscience Letters.

[3]  S. Hillyard,et al.  Human auditory evoked potentials. I. Evaluation of components. , 1974, Electroencephalography and clinical neurophysiology.

[4]  R. Ilmoniemi,et al.  A 24-Channel Magnetometer for Brain Research , 1989 .

[5]  Robert A. Levine,et al.  Binaural interaction in brainstem potentials of human subjects , 1981, Annals of neurology.

[6]  Seppo P. Ahlfors,et al.  Large-area low-noise seven-channel dc SQUID magnetometer for brain research , 1987 .

[7]  M. Pelizzone,et al.  Electrically evoked responses in Cochlear implant patients. , 1989, Audiology : official organ of the International Society of Audiology.

[8]  P. Stypulkowski,et al.  Characterization of the electrically evoked auditory brainstem response (ABR) in cats and humans , 1986, Hearing Research.

[9]  M. Pelizzone,et al.  Binaural interaction in a cochlear implant patient , 1990, Hearing Research.

[10]  Carolyn J Brown,et al.  Electrically evoked brainstem potentials in cochlear implant patients with multi-electrode stimulation , 1988, Hearing Research.

[11]  D L Jewett,et al.  Auditory-evoked far fields averaged from the scalp of humans. , 1971, Brain : a journal of neurology.

[12]  Francis Kuk,et al.  Evaluation of five different cochlear implant designs: Audiologic assessment and predictors of performance , 1988, The Laryngoscope.

[13]  R. Hari,et al.  Recording and interpretation of cerebral magnetic fields. , 1989, Science.

[14]  Cortical activity evoked by a multichannel cochlear prosthesis. , 1987, Acta oto-laryngologica.