Stepwise quantitative risk assessment as a tool for characterization of microbiological food safety

This paper describes a system for the microbiological quantitative risk assessment for food products and their production processes. The system applies a stepwise risk assessment, allowing the main problems to be addressed before focusing on less important problems. First, risks are assessed broadly, using order of magnitude estimates. Characteristic numbers are used to quantitatively characterize microbial behaviour during the production process. These numbers help to highlight the major risk‐determining phenomena, and to find negligible aspects. Second, the risk‐determining phenomena are studied in more detail. Both general and/or specific models can be used for this and varying situations can be simulated to quantitatively describe the risk‐determining phenomena. Third, even more detailed studies can be performed where necessary, for instance by using stochastic variables. The system for quantitative risk assessment has been implemented as a decision supporting expert system called SIEFE: Stepwise and Interactive Evaluation of Food safety by an Expert System. SIEFE performs bacterial risk assessments in a structured manner, using various information sources. Because all steps are transparent, every step can easily be scrutinized.

[1]  R. R. Beumer,et al.  A risk assessment study of Bacillus cereus present in pasteurized milk. , 1997 .

[2]  H M Marks,et al.  Topics in Microbial Risk Assessment: Dynamic Flow Tree Process , 1998, Risk analysis : an official publication of the Society for Risk Analysis.

[3]  K van't Riet,et al.  A decision support system for the prediction of microbial food safety and food quality. , 1998, International journal of food microbiology.

[4]  James M. Jay,et al.  Modern food microbiology , 1970 .

[5]  Marijana Carić,et al.  Processed cheese products. , 1993 .

[6]  S J van Gerwen,et al.  Growth and inactivation models to be used in quantitative risk assessments. , 1998, Journal of food protection.

[7]  Mgb,et al.  The dose-response relation in human volunteers forgastro-intestinal pathogens , 1996 .

[8]  W B McNab A general framework illustrating an approach to quantitative microbial food safety risk assessment. , 1998, Journal of food protection.

[9]  Mark W. LeChevallier,et al.  A conceptual framework to assess the risks of human disease following exposure to pathogens. ILSI Risk Science Institute Pathogen Risk Assessment Working Group. , 1996, Risk analysis : an official publication of the Society for Risk Analysis.

[10]  R. D. Foltz CRC Handbook of Chemistry and Physics:A Ready-Reference Book of Chemical and Physical Data , 2000 .

[11]  Clifford J. Cremers,et al.  Thermal Properties of Foods and Agricultural Materials , 1981 .

[12]  N. N. Mohsenin,et al.  Thermal Properties of Food and Agricultural Materials , 1980 .

[13]  R. C. Whiting,et al.  Development of a quantitative risk assessment model for Salmonella enteritidis in pasteurized liquid eggs. , 1997, International journal of food microbiology.

[14]  J P Flandrois,et al.  Convenient Model To Describe the Combined Effects of Temperature and pH on Microbial Growth , 1995, Applied and environmental microbiology.

[15]  J Baranyi,et al.  A dynamic approach to predicting bacterial growth in food. , 1994, International journal of food microbiology.

[16]  Kenneth W. Davies,et al.  Quantitative microbiological risk assessment: principles applied to determining the comparative risk of salmonellosis from chicken products. , 1998, Journal of food protection.

[17]  R. Wagenaar,et al.  Factors Influencing Growth and Toxin Production in Cheese Inoculated with Spores of Clostridium Botulinum Types A and B. III. Studies with Surface-Ripened Cheese Type III , 1958 .

[18]  N. Bean,et al.  Foodborne Disease Outbreaks in the United States, 1973-1987: Pathogens, Vehicles, and Trends. , 1990, Journal of food protection.

[19]  R. C. Whiting,et al.  Use of Epidemiologic and Food Survey Data To Estimate a Purposefully Conservative Dose-Response Relationship for Listeria monocytogenes Levels and Incidence of Listeriosis †. , 1997, Journal of food protection.

[20]  N Bemrah,et al.  Quantitative risk assessment of human listeriosis from consumption of soft cheese made from raw milk. , 1998, Preventive veterinary medicine.

[21]  M. Doyle,et al.  Foodborne bacterial pathogens , 1989 .

[22]  Marcel H. Zwietering,et al.  Modelling the hygienic processing of foods - influence of individual process stages. , 1997 .

[23]  F. Rombouts,et al.  Modeling of the Bacterial Growth Curve , 1990, Applied and environmental microbiology.

[24]  P J McClure,et al.  Quantitative microbiological risk assessment: principles applied to determining the comparative risk of salmonellosis from chicken products. , 1998, Journal of food protection.

[25]  P. F. ter Steeg,et al.  Growth of Proteolytic Clostridium botulinum in Process Cheese Products: II. Predictive Modeling. , 1995, Journal of food protection.

[26]  E. H. Marth,et al.  Microbial Survival in the Environment: Bacteria and Rickettsiae Important in Human and Animal Health , 1984 .

[27]  E. Todd,et al.  Preliminary Estimates of Costs of Foodborne Disease in the United States. , 1989, Journal of food protection.

[28]  Thomas P. Oscar,et al.  THE DEVELOPMENT OF A RISK ASSESSMENT MODEL FOR USE IN THE POULTRY INDUSTRY , 1998 .

[29]  F. M. Rombouts,et al.  Incidence and characterization of Bacillus cereus in two dairy processing plants. , 1996 .

[30]  S J van Gerwen,et al.  An identification procedure for foodborne microbial hazards. , 1997, International journal of food microbiology.

[31]  Mark E. Johnson,et al.  Microbiological Safety of Cheese Made from Heat-Treated Milk, Part II. Microbiology. , 1990, Journal of food protection.

[32]  G. Tegge Tschubik, I. A., und A. M. Maslow: Wärmephysikalische Konstanten von Lebensmitteln und Halbfabrikaten. Übersetzung aus dem Russischen. VEB Fachbuchverlag Leipzig 1973, 1. Auflage, 176 Seiten, 39 Abb., 261 Tab., 14,7 cm X 21,5 cm, Halbgewebeeinband, Preis 14,80 M , 1974 .

[33]  Choice of sampling plan and criteria for Listeria monocytogenes. International Commission on Microbiological Specifications for Foods. , 1994, International journal of food microbiology.

[34]  F. M. Rombouts,et al.  Incidence of Bacillus cereus and Bacillus subtilis in foods in the Netherlands. , 1996 .

[35]  H. Lewerenz,et al.  Joint FAO/WHO food standards programme, codex alimentarius commission: List of additives evaluated for their safety‐in‐use in food. First Series. 88 Seiten. FAO and WHO, 1973. Preis: 1.— $ , 1976 .

[36]  Charles P. Gerba,et al.  LINKING MICROBIOLOGICAL CRITERIA FOR FOODS WITH QUANTITATIVE RISK ASSESSMENT , 1995 .

[37]  J. C. de Wit,et al.  Some aspects of microbial contamination of hands of workers in food industries. , 1981, Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale B, Hygiene.

[38]  M H Cassin,et al.  Quantitative risk assessment for Escherichia coli O157:H7 in ground beef hamburgers. , 1998, International journal of food microbiology.

[39]  S. Loncarevic,et al.  Occurrence of Listeria monocytogenes in soft and semi-soft cheeses in retail outlets in Sweden. , 1995, International journal of food microbiology.

[40]  C N Haas,et al.  Risk assessment of virus in drinking water. , 1993, Risk analysis : an official publication of the Society for Risk Analysis.

[41]  N. Bean,et al.  Surveillance for foodborne-disease outbreaks--United States, 1988-1992. , 1996, MMWR. CDC surveillance summaries : Morbidity and mortality weekly report. CDC surveillance summaries.

[42]  M H Zwietering,et al.  Application of predictive microbiology to estimate the number of Bacillus cereus in pasteurised milk at the point of consumption. , 1996, International journal of food microbiology.

[43]  Dr. Dr. h.c. Eilhard Mitscherlich,et al.  Microbial Survival in the Environment , 1984, Springer Berlin Heidelberg.

[44]  C N Haas,et al.  Estimation of risk due to low doses of microorganisms: a comparison of alternative methodologies. , 1983, American journal of epidemiology.

[45]  David A Shapton,et al.  Principles and practices for the safe processing of foods , 1993 .

[46]  J. Chirife,et al.  Clostridium botulinum Type A Growth and Toxin Production in Media and Process Cheese Spread , 1983, Applied and environmental microbiology.

[47]  Charles P. Gerba,et al.  Use of Risk Assessment for Development of Microbial Standards , 1991 .