Organ motion due to respiration: the state of the art and applications in interventional radiology and radiation oncology

Tracking organ motion due to respiration is important for precision treatments in interventional radiology and radiation oncology, among other areas. In interventional radiology, the ability to track and compensate for organ motion could lead to more precise biopsies for applications such as lung cancer screening. In radiation oncology, image-guided treatment of tumors is becoming technically possible, and the management of organ motion then becomes a major issue. This paper will review the state-of-the-art in respiratory motion and present two related clinical applications. Respiratory motion is an important topic for future work in image-guided surgery and medical robotics. Issues include how organs move due to respiration, how much they move, how the motion can be compensated for, and what clinical applications can benefit from respiratory motion compensation. Technology that can be applied for this purpose is now becoming available, and as that technology evolves, the subject will become an increasingly interesting and clinically valuable topic of research.

[1]  K. Langen,et al.  Organ motion and its management. , 2001, International journal of radiation oncology, biology, physics.

[2]  Hans-Ulrich Kauczor,et al.  Analysis of intrathoracic tumor mobility during whole breathing cycle by dynamic MRI. , 2004, International journal of radiation oncology, biology, physics.

[3]  E. Yorke,et al.  Deep inspiration breath hold and respiratory gating strategies for reducing organ motion in radiation treatment. , 2004, Seminars in radiation oncology.

[4]  Jean-Claude Latombe,et al.  Image-Guided Robotic Radiosurgery , 1994, Modelling and Planning for Sensor Based Intelligent Robot Systems.

[5]  K. Cleary,et al.  Assessment of hepatic motion secondary to respiration for computer assisted interventions. , 2002, Computer aided surgery : official journal of the International Society for Computer Aided Surgery.

[6]  J. Wong,et al.  The use of active breathing control (ABC) to reduce margin for breathing motion. , 1999, International journal of radiation oncology, biology, physics.

[7]  Steve B. Jiang,et al.  The management of respiratory motion in radiation oncology report of AAPM Task Group 76. , 2006, Medical physics.

[8]  Kevin Cleary,et al.  A robotic 3-D motion simulator for enhanced accuracy in CyberKnife stereotactic radiosurgery , 2004, CARS.

[9]  M. V. van Herk,et al.  Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. , 2002, International journal of radiation oncology, biology, physics.

[10]  Lili Wang,et al.  Introduction of audio gating to further reduce organ motion in breathing synchronized radiotherapy. , 2002, Medical physics.

[11]  Russell H. Taylor,et al.  3D motion tracking of pulmonary lesions using CT fluoroscopy images for robotically assisted lung biopsy , 2004, Medical Imaging: Image-Guided Procedures.

[12]  Dan Stoianovici,et al.  AcuBot: a robot for radiological interventions , 2003, IEEE Trans. Robotics Autom..

[13]  Jean-Philippe Pignol,et al.  Correlation of lung tumor motion with external surrogate indicators of respiration. , 2004, International journal of radiation oncology, biology, physics.