Gender-specific presentations for asthma, allergic rhinitis and eczema in primary care.

AIM To identify age- and gender-specific prevalence rates for physician-diagnosed asthma, allergic rhinitis (AR) and eczema across a whole lifespan. METHOD Presentations of asthma, allergic rhinitis and eczema were identified in individuals aged 0 to 65 who consulted their general practitioner at least once in 1998-99 from a population sample of 266,733 in Scotland, and in 1991-95 for asthma and allergic rhinitis in 6,836,063 person years at risk in England and Wales. RESULTS In both sexes asthma presentations peak at 4-6 years whilst eczema peaks in infancy. A second asthma peak occurs during adolescence, earlier in females, at a time when a female predominance for all three atopic diseases is established. Female predominance of eczema presentations are limited to the reproductive period of 15-49 years. CONCLUSION The patterns of presentations for asthma, allergic rhinitis and eczema by age and gender suggest important gender-specific differences in disease predisposition and diagnosis.

[1]  A. Maryon-Davis,et al.  Epidemiology and Public Health , 2020, Medicine for MRCP.

[2]  B. Burrows,et al.  Comparisons of asthma, emphysema, and chronic bronchitis diagnoses in a general population sample. , 2015, The American review of respiratory disease.

[3]  D. Halpin,et al.  How accurate is diagnosis of asthma in a general practice database? A review of patients' notes and questionnaire-reported symptoms. , 2004, The British journal of general practice : the journal of the Royal College of General Practitioners.

[4]  Nicky Richards,et al.  Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD) , 2003, BMC family practice.

[5]  M. Osman Therapeutic implications of sex differences in asthma and atopy , 2003, Archives of disease in childhood.

[6]  T. Holmen,et al.  Gender differences in asthma prevalence may depend on how asthma is defined. , 2003, Respiratory medicine.

[7]  W. Kiess,et al.  Puberty and prognosis of asthma and bronchial hyper‐reactivity , 2001, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[8]  N. Shamsian,et al.  Prevalence and severity of asthma, rhinitis, and atopic eczema in 13- to 14-year-old schoolchildren from the northeast of England. , 2001, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[9]  Colin Simpson,et al.  Respiratory morbidity in primary care. A population based study, using practices from the Scottish Continuous Morbidity Recording Research Database. , 2000, Health bulletin.

[10]  R. Stockley,et al.  Physiological and radiological characterisation of patients diagnosed with chronic obstructive pulmonary disease in primary care , 2000, Thorax.

[11]  S. Mckenzie,et al.  What do parents of wheezy children understand by “wheeze”? , 2000, Archives of disease in childhood.

[12]  N. Shamsian,et al.  Prevalence and severity of asthma, rhinitis, and atopic eczema: the north east study , 1999, Archives of disease in childhood.

[13]  A. Hansell,et al.  Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity Survey in General Practice (MSGP4) , 1999, Thorax.

[14]  Azeem Majeed,et al.  Socioeconomic differences in childhood consultation rates in general practice in England and Wales: prospective cohort study , 1999, BMJ.

[15]  M. Gissler,et al.  Boys have more health problems in childhood than girls: follow‐up of the 1987 Finnish birth cohort , 1999, Acta paediatrica.

[16]  Caroline C. Whitacre,et al.  A Gender Gap in Autoimmunity , 1999, Science.

[17]  P. Vermeire,et al.  Gender differences in respiratory, nasal and skin symptoms: 6–7 versus 13–14‐year‐old children , 1999, Acta paediatrica.

[18]  S. Lewis,et al.  Questionnaire study of effect of sex and age on the prevalence of wheeze and asthma in adolescence , 1998, BMJ.

[19]  D. Strachan,et al.  Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort , 1996, BMJ.

[20]  D. Rigopoulos,et al.  Influence of the menstrual cycle on skin‐prick test reactions to histamine, morphine and allergen , 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[21]  M. Rosenthal,et al.  Lung function in white children aged 4 to 19 years: I--Spirometry. , 1993, Thorax.

[22]  N. Wilson,et al.  Wheezy bronchitis revisited. , 1989, Archives of disease in childhood.

[23]  K. Rogers,et al.  A sex difference in immunologic responsiveness. , 1971, Pediatrics.

[24]  W P LOGAN,et al.  Morbidity statistics from general practice. , 1954, The Practitioner.

[25]  Ian Matthews,et al.  Epidemiology and public health , 1999 .

[26]  M. Bruijnzeels,et al.  Everyday symptoms in childhood: occurrence and general practitioner consultation rates. , 1998, The British journal of general practice : the journal of the Royal College of General Practitioners.

[27]  R. Zannolli,et al.  Does puberty interfere with asthma? , 1997, Medical hypotheses.

[28]  H F Sanderson,et al.  A language of health in action: Read Codes, classifications and groupings. , 1996, Proceedings : a conference of the American Medical Informatics Association. AMIA Fall Symposium.

[29]  B. Burrows,et al.  The prevalence and incidence of asthma and asthma-like symptoms in a general population sample. , 1980, The American review of respiratory disease.