Staphylococcal spheroplasts and L-colonies. 3. Induction by lysostaphin.

The bacteriolytic enzyme, lysostaphin, first discovered by Schindler and Schuhardt [1, 2], has the unique property of rapidly and specifically lysing staphylococci but not bacteria of other genera. Lysostaphin alone [3-6] or in conjunction with methicillin [7] has been shown to be efficacious in the treatment of experimental staphylococcal infection in mice. Preliminary observations indicate that it is effective in the

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