Treatment of partial‐thickness burns: a prospective, randomized trial using TranscyteTM

Background:  The purpose of the present study was to compare the effectiveness of three burns dressings (TransCyte, a bio‐engineered skin substitute; Biobrane; and Silvazine cream (silver sulphadiazine and 0.2% chlorhexidine)), in treating children with partial‐thickness burns. The primary objective was to determine the days until ≥90% re‐epithelialization. The secondary objectives were to evaluate the number of wounds requiring autografting and the number of dressing changes/local wound care required.

[1]  C. Gotschall,et al.  Patterns of injury in children. , 1990, Journal of pediatric surgery.

[2]  K. Newman,et al.  The use of a bioactive skin substitute decreases length of stay for pediatric burn patients. , 2001, Journal of pediatric surgery.

[3]  M. Härmä,et al.  [Management of burn injuries]. , 1996, Duodecim lääketieteellinen aikakauskirja.

[4]  R. Demling,et al.  Management of partial thickness facial burns (comparison of topical antibiotics and bio-engineered skin substitutes). , 1999, Burns : journal of the International Society for Burn Injuries.

[5]  J. Hansbrough,et al.  Safety and efficacy of TransCyte for the treatment of partial-thickness burns. , 1999, The Journal of burn care & rehabilitation.

[6]  T. Lukens,et al.  Outpatient management of partial-thickness burns: Biobrane versus 1% silver sulfadiazine. , 1990, Annals of emergency medicine.

[7]  J. Hansbrough,et al.  Clinical experience with Biobrane biosynthetic dressing in the treatment of partial thickness burns. , 1984, Burns, including thermal injury.

[8]  J. Hansbrough,et al.  Clinical trials of a biosynthetic temporary skin replacement, Dermagraft-Transitional Covering, compared with cryopreserved human cadaver skin for temporary coverage of excised burn wounds. , 1997, The Journal of burn care & rehabilitation.

[9]  E. Deitch,et al.  Hypertrophic burn scars: analysis of variables. , 1983, The Journal of trauma.

[10]  J. Hansbrough.  Dermagraft-TC for partial-thickness burns: a clinical evaluation. , 1997, The Journal of burn care & rehabilitation.

[11]  L D Solem,et al.  A multicenter clinical trial of a biosynthetic skin replacement, Dermagraft-TC, compared with cryopreserved human cadaver skin for temporary coverage of excised burn wounds. , 1997, The Journal of burn care & rehabilitation.