Neurosurgical Defeats: Critically Ill Patients and the Role of Palliative Care Service

The onco-functional balance in neuro-oncology requires maximizing tumor removal while rigorously preserving patients’ neurological status. When postoperative worsening prevents the implementation of oncologic treatments, palliative care service offers an individualized path for symptom and psychosocial distress relief. Here, we report on a series of 25 patients operated on for malignant brain tumor who did not undergo adjuvant treatments after neurosurgery; they represented 3.9% of the whole institutional surgical series. These patients were significantly older and had a lower preoperative Karnofsky performance status than the whole cohort. Importantly, in 22 out of 25 (88%) cases, a surgical complication occurred, leading to clinical worsening in 21 patients. For the end of life, the majority of patients chose a hospice care facility (72%). While a careful selection of brain tumor patients candidate to neurosurgery is required, palliative care service provided invaluable help in coping with patients’ and caregivers’ needs.

[1]  A. Olivi,et al.  Molecular Analysis in a Glioblastoma Cohort—Results of a Prospective Analysis , 2022, Journal of personalized medicine.

[2]  A. Olivi,et al.  Neuro-Oncology Multidisciplinary Tumor Board: The Point of View of the Neuroradiologist , 2022, Journal of personalized medicine.

[3]  D. Brain,et al.  Economic Evaluation of Long-Term Survivorship Care for Cancer Patients in OECD Countries: A Systematic Review for Decision-Makers , 2021, International journal of environmental research and public health.

[4]  A. Olivi,et al.  Reassessing the Role of Brain Tumor Biopsy in the Era of Advanced Surgical, Molecular, and Imaging Techniques—A Single-Center Experience with Long-Term Follow-Up , 2021, Journal of personalized medicine.

[5]  A. Jemal,et al.  Brain and other central nervous system tumor statistics, 2021 , 2021, CA: a cancer journal for clinicians.

[6]  S. Goyal,et al.  Trends in inpatient palliative care use for primary brain malignancies , 2021, Supportive Care in Cancer.

[7]  G. Reifenberger,et al.  EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood , 2020, Nature Reviews Clinical Oncology.

[8]  K. Mishima,et al.  Current Status of Palliative and Terminal Care for Patients with Primary Malignant Brain Tumors in Japan , 2020, Neurologia medico-chirurgica.

[9]  M. Niewada,et al.  Overview and Analysis of the Cost of Drug Programs in Poland: Public Payer Expenditures and Coverage of Cancer and Non-Neoplastic Diseases Related Drug Therapies from 2015–2018 Years , 2020, Frontiers in Pharmacology.

[10]  M. J. van den Bent,et al.  Determining medical decision-making capacity in brain tumor patients: why and how? , 2020, Neuro-oncology practice.

[11]  M. Weller,et al.  European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma. , 2017, The Lancet. Oncology.

[12]  C. Stewart‐Amidei,et al.  A new reality: long-term survivorship with a malignant brain tumor. , 2013, Oncology nursing forum.