Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer

[1]  Chie-Pein Chen,et al.  Transforming growth factor-beta induces CD44 cleavage that promotes migration of MDA-MB-435s cells through the up-regulation of membrane type 1-matrix metalloproteinase. , 2009, International journal of cancer.

[2]  M. Poupon,et al.  CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts , 2009, British Journal of Cancer.

[3]  L. Leng,et al.  Tumor growth-promoting properties of macrophage migration inhibitory factor. , 2008, Current pharmaceutical design.

[4]  J. Bernhagen,et al.  Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment , 2008, Proceedings of the National Academy of Sciences.

[5]  R. Bucala,et al.  Cooperative Regulation of Non-Small Cell Lung Carcinoma Angiogenic Potential by Macrophage Migration Inhibitory Factor and Its Homolog, d-Dopachrome Tautomerase1 , 2008, The Journal of Immunology.

[6]  T. Taylor,et al.  Regulation of inflammation- and angiogenesis-related gene expression in breast cancer cells and co-cultured macrophages. , 2008, Anticancer research.

[7]  I. Giannopoulou,et al.  The clinicopathologic and prognostic significance of CD44+/CD24(-/low) and CD44-/CD24+ tumor cells in invasive breast carcinomas. , 2008, Human pathology.

[8]  E. Dahl,et al.  Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer , 2008, BMC Cancer.

[9]  J. Bernhagen,et al.  Macrophage Migration Inhibitory Factor in Cardiovascular Disease , 2008, Circulation.

[10]  Bo Wang,et al.  Overexpression of macrophage migration inhibitory factor induces angiogenesis in human breast cancer. , 2008, Cancer letters.

[11]  L. Leng,et al.  Macrophage Migration Inhibitory Factor Induces B Cell Survival by Activation of a CD74-CD44 Receptor Complex* , 2008, Journal of Biological Chemistry.

[12]  Hwai-Shi Wang,et al.  CD44 crosslinking-mediated matrix metalloproteinase-9 relocation in breast tumor cells leads to enhanced metastasis. , 2007, International journal of oncology.

[13]  J. Bernhagen,et al.  Macrophage migration inhibitory factor (MIF) promotes fibroblast migration in scratch‐wounded monolayers in vitro , 2007, FEBS letters.

[14]  D. Goldenberg,et al.  CD74: A New Candidate Target for the Immunotherapy of B-Cell Neoplasms , 2007, Clinical Cancer Research.

[15]  E. Dahl,et al.  Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity , 2007, Oncogene.

[16]  J. Bernhagen,et al.  MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment , 2007, Nature Medicine.

[17]  G. Fingerle-Rowson,et al.  Impaired DNA damage checkpoint response in MIF‐deficient mice , 2007, The EMBO journal.

[18]  K. Iczkowski,et al.  Inhibition of Macrophage Migration Inhibitory Factor or Its Receptor (CD74) Attenuates Growth and Invasion of DU-145 Prostate Cancer Cells1 , 2006, The Journal of Immunology.

[19]  L. Leng,et al.  CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. , 2006, Immunity.

[20]  Christian Pilarsky,et al.  Molecular Profiling of Laser-Microdissected Matched Tumor and Normal Breast Tissue Identifies Karyopherin α2 as a Potential Novel Prognostic Marker in Breast Cancer , 2006, Clinical Cancer Research.

[21]  J. Bernhagen,et al.  MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis , 2006, Nature Reviews Drug Discovery.

[22]  J. Bernhagen,et al.  Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity. , 2006, Cellular signalling.

[23]  Lin Leng,et al.  Macrophage migration inhibitory factor promotes intestinal tumorigenesis. , 2005, Gastroenterology.

[24]  J. Bernhagen,et al.  Link between macrophage migration inhibitory factor and cellular redox regulation. , 2005, Antioxidants & redox signaling.

[25]  T. Hagemann,et al.  Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK1 , 2005, The Journal of Immunology.

[26]  K. Iczkowski,et al.  Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer , 2005, BMC Cancer.

[27]  Terry L. Smith,et al.  CD44 Expression Is Associated with Increased Survival in Node-Negative Invasive Breast Carcinoma , 2005, Clinical Cancer Research.

[28]  Maria Athelogou,et al.  Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[29]  K. Meyer-Siegler,et al.  Inhibition of macrophage migration inhibitory factor decreases proliferation and cytokine expression in bladder cancer cells , 2004, BMC Cancer.

[30]  Michael Bacher,et al.  Macrophage migration inhibitory factor: Roles in regulating tumor cell migration and expression of angiogenic factors in hepatocellular carcinoma , 2003, International journal of cancer.

[31]  T. Calandra,et al.  Macrophage migration inhibitory factor: a regulator of innate immunity , 2003, Nature Reviews Immunology.

[32]  J. Bernhagen,et al.  Regulated secretion of macrophage migration inhibitory factor is mediated by a non‐classical pathway involving an ABC transporter , 2003, FEBS letters.

[33]  O. Petrenko,et al.  The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[34]  L. Leng,et al.  MIF Signal Transduction Initiated by Binding to CD74 , 2003, The Journal of experimental medicine.

[35]  C. Kittas,et al.  Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1). , 2003, Cancer research.

[36]  J. Bernhagen,et al.  The Cytokine Macrophage Migration Inhibitory Factor Reduces Pro-Oxidative Stress-Induced Apoptosis1 , 2003, The Journal of Immunology.

[37]  N. Funata,et al.  Expression of Macrophage Migration Inhibitory Factor in Human Breast Cancer: Association with Nodal Spread , 2002, Japanese journal of cancer research : Gann.

[38]  J. Bernhagen,et al.  Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. , 2002, Microbes and infection.

[39]  John David,et al.  Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[40]  R. Kleemann,et al.  Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF. , 2001, European journal of biochemistry.

[41]  F. Spyratos,et al.  Relationship between c-erbB-2 and other tumor characteristics in breast cancer prognosis. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[42]  J. Bernhagen,et al.  Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1 , 2000, Nature.

[43]  R. Bucala,et al.  Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF). , 2000, Seminars in cancer biology.

[44]  E. Milgrom,et al.  JAB1 Interacts with Both the Progesterone Receptor and SRC-1* , 2000, The Journal of Biological Chemistry.

[45]  G. Hannon,et al.  A Proinflammatory Cytokine Inhibits P53 Tumor Suppressor Activity , 1999, The Journal of experimental medicine.

[46]  M. Suzuki,et al.  High expression of macrophage migration inhibitory factor in human melanoma cells and its role in tumor cell growth and angiogenesis. , 1999, Biochemical and biophysical research communications.

[47]  Tina Peng,et al.  Sustained Mitogen-activated Protein Kinase (MAPK) and Cytoplasmic Phospholipase A2 Activation by Macrophage Migration Inhibitory Factor (MIF) , 1999, The Journal of Biological Chemistry.

[48]  J. Kato,et al.  Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1 , 1999, Nature.

[49]  R. Bucala,et al.  An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma , 1999, Molecular medicine.

[50]  Yuji Sato,et al.  Involvement of Macrophage Migration Inhibitory Factor (MIF) in the Mechanism of Tumor Cell Growth , 1998, Molecular medicine.

[51]  Yuji Sato,et al.  Macrophage Migration Inhibitory Factor (MIF) , 1996 .

[52]  W. Remmele,et al.  [Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]. , 1987, Der Pathologe.

[53]  Julia L. Gregory,et al.  Macrophage Migration Inhibitory Factor Induces Macrophage Recruitment via CC Chemokine Ligand 2 , 2006 .

[54]  T. Hagemann,et al.  Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. , 2005, Journal of immunology.

[55]  Yuji Sato,et al.  Macrophage migration inhibitory factor (MIF): Its potential role in tumor growth and tumor-associated angiogenesis. , 2003, Annals of the New York Academy of Sciences.

[56]  L. Sobin,et al.  TNM Classification of Malignant Tumours , 1987, UICC International Union Against Cancer.