Bilateral alterations in somatosensory cortical processing in hemiplegic cerebral palsy

Aim  In individuals with cerebral palsy (CP), cerebral insults during early development may induce profound reorganization of the motor representation. This study determined the extent of alterations in cortical somatosensory functions in adolescents with hemiplegic CP with subcortical brain lesions.

[1]  G. Cioni,et al.  Reorganisation of the somatosensory system after early brain damage , 2007, Clinical Neurophysiology.

[2]  Yoshio Okada,et al.  Immaturity of somatosensory cortical processing in human newborns , 2006, NeuroImage.

[3]  N Forss,et al.  Lack of activation of human secondary somatosensory cortex in Unverricht‐Lundborg type of progressive myoclonus epilepsy , 2001, Annals of neurology.

[4]  S. Taulu,et al.  Spatiotemporal signal space separation method for rejecting nearby interference in MEG measurements , 2006, Physics in medicine and biology.

[5]  J Huttunen Does the P35m SEF deflection really come from the motor cortex? , 1997, Electroencephalography and clinical neurophysiology.

[6]  Wolfgang Grodd,et al.  Reorganization in congenital hemiparesis acquired at different gestational ages , 2004, Annals of neurology.

[7]  Nina Forss,et al.  Mirror-like spread of chronic pain , 2005, Neurology.

[8]  T. Elbert,et al.  Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation , 1995, Nature.

[9]  A. Bastian,et al.  Sensory and motor deficits in children with cerebral palsy born preterm correlate with diffusion tensor imaging abnormalities in thalamocortical pathways , 2009, Developmental medicine and child neurology.

[10]  W M Jenkins,et al.  A primate model for studying focal dystonia and repetitive strain injury: effects on the primary somatosensory cortex. , 1997, Physical therapy.

[11]  C. Cans Surveillance of cerebral palsy in Europe: a collaboration of cerebral palsy surveys and registers , 2000, Developmental medicine and child neurology.

[12]  Xiaoqin Wang,et al.  Remodelling of hand representation in adult cortex determined by timing of tactile stimulation , 1995, Nature.

[13]  M. Erb,et al.  Developing somatosensory projections bypass periventricular brain lesions , 2006, Neurology.

[14]  B. Rockstroh,et al.  Alteration of digital representations in somatosensory cortex in focal hand dystonia , 1998, Neuroreport.

[15]  Milos Judas,et al.  Correlation between the sequential ingrowth of afferents and transient patterns of cortical lamination in preterm infants , 2002, The Anatomical record.

[16]  R. Llinás,et al.  Somatosensory cortical plasticity in adult humans revealed by magnetoencephalography. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[17]  M. Calford,et al.  Interhemispheric modulation of somatosensory receptive fields: evidence for plasticity in primary somatosensory cortex. , 1996, Cerebral cortex.

[18]  R. Hari,et al.  Modified activation of somatosensory cortical network in patients with right-hemisphere stroke. , 1999, Brain : a journal of neurology.

[19]  Mary F. Barbe,et al.  Impact of neonatal asphyxia and hind limb immobilization on musculoskeletal tissues and S1 map organization: Implications for cerebral palsy , 2008, Experimental Neurology.

[20]  R. Ilmoniemi,et al.  Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain , 1993 .

[21]  Antti Korvenoja,et al.  Activation of ipsilateral primary sensorimotor cortex by median nerve stimulation , 1995, Neuroreport.

[22]  Michael Erb,et al.  Two types of ipsilateral reorganization in congenital hemiparesis: a TMS and fMRI study. , 2002, Brain : a journal of neurology.

[23]  P. Rossini,et al.  Carpal tunnel syndrome modifies sensory hand cortical somatotopy: A MEG study , 2002, Human brain mapping.

[24]  A. Eliasson,et al.  The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability. , 2006, Developmental medicine and child neurology.

[25]  M. Merzenich,et al.  Reorganization of somatosensory area 3b representations in adult owl monkeys after digital syndactyly. , 1991, Journal of neurophysiology.