论文信息 - sTREM-1 is a specific biomarker of TREM-1 pathway activation - 字舞流文

sTREM-1 is a specific biomarker of TREM-1 pathway activation

A. Mebazaa | T. van der Poll | P. Laterre | J. Garaud | S. Lambden | S. Gibot | M. Derive | A. Boufenzer | L. Jolly | K. Carrasco | Margarita Salcedo-Magguilli

[1] S. Gibot,et al. Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis , 2021, Cellular & Molecular Immunology.

[2] F. Vandenhende,et al. Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial , 2020, Intensive Care Medicine.

[3] A. Heck,et al. TREM-1 multimerization is essential for its activation on monocytes and neutrophils , 2019, Cellular & Molecular Immunology.

[4] J. Lemarié,et al. Targeted endothelial gene deletion of triggering receptor expressed on myeloid cells-1 protects mice during septic shock , 2018, Cardiovascular research.

[5] G. Xin,et al. Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors , 2016, Mucosal Immunology.

[6] Felipe García,et al. Metalloproteinases Shed TREM-1 Ectodomain from Lipopolysaccharide-Stimulated Human Monocytes1 , 2007, The Journal of Immunology.

[7] M. Colonna,et al. Cutting Edge: Inflammatory Responses Can Be Triggered by TREM-1, a Novel Receptor Expressed on Neutrophils and Monocytes1 , 2000, The Journal of Immunology.