Conceptual Design of Azeotropic Distillation Processes

Abstract This chapter introduces the major types of azeotropic distillation processes and describes a systematic framework for their conceptual design. The framework is based on a three-step approach consisting of (1) variant generation, (2) screening of all variants based on shortcut methods, and (3) the final detailed design by means of rigorous optimization. Different approaches for the generation of distillation flowsheets and the analysis of inherent limitations are presented and compared in the context of a qualitative and quantitative assessment of split feasibility. An elaborate overview on different shortcut methods for the evaluation of distillation process performance is given, and their applicability to the design of azeotropic distillation processes is discussed. Since rigorous optimization should always follow shortcut-based design and evaluation steps, recent advances in this field with a focus on azeotropic distillation are highlighted. The chapter closes with the presentation of a few example case studies for the conceptual design of different types of azeotropic distillation processes.

[1]  Michael F. Malone,et al.  Structure of Distillation Regions for Multicomponent Azeotropic Mixtures , 1998 .

[2]  E. Blass,et al.  Best products of homogeneous azeotropic distillations , 1994 .

[3]  S. O. Momoh,et al.  Assessing the Accuracy of Selectivity as a Basis for Solvent Screening in Extractive Distillation Processes , 1991 .

[4]  Michael F. Doherty,et al.  A simple exact method for calculating tangent pinch points in multicomponent nonideal mixtures by bifurcation theory , 1986 .

[5]  Michael F. Doherty,et al.  Design and synthesis of homogeneous azeotropic distillations. 4. Minimum reflux calculations for multiple-feed columns , 1986 .

[6]  Michael F. Doherty,et al.  Design and synthesis of homogeneous azeotropic distillations. 2. Minimum reflux calculations for nonideal and azeotropic columns , 1985 .

[7]  Ignacio E. Grossmann,et al.  Alternative representations and formulations for the economic optimization of multicomponent distillation columns , 2003, Comput. Chem. Eng..

[8]  Manfred Morari,et al.  Homogeneous azeotropic distillation: separability and flowsheet synthesis , 1992 .

[9]  J. Stichlmair,et al.  Separation regions and processes of zeotropic and azeotropic ternary distillation , 1992 .

[10]  Y. A. Liu,et al.  Heuristic Synthesis and Shortcut Design of Separation Processes Using Residue Curve Maps: A Review , 1994 .

[11]  Wolfgang Marquardt,et al.  Rapid screening of design alternatives for nonideal multiproduct distillation processes , 2004, Comput. Chem. Eng..

[12]  Wolfgang Marquardt,et al.  Quick and reliable phase stability test in VLLE flash calculations by homotopy continuation , 2000 .

[13]  L. T. Fan,et al.  Graph-theoretic method for the algorithmic synthesis of azeotropic-distillation systems , 2003 .

[14]  Nuno M. C. Oliveira,et al.  A robust strategy for optimizing complex distillation columns , 2005, Comput. Chem. Eng..

[15]  M. Morari,et al.  Multiple steady states in heterogeneous azeotropic distillation , 1993 .

[16]  Michael F. Doherty,et al.  Design and synthesis of heterogeneous azeotropic distillations—III. Column sequences , 1990 .

[17]  C. Pantelides,et al.  Optimal design of thermally coupled distillation columns , 1999 .

[18]  M. F. Malone,et al.  Feasibility of separations for distillation of nonideal ternary mixtures , 1993 .

[19]  E. Blass,et al.  A review on minimum energy calculations for ideal and nonideal distillations , 1995 .

[20]  Wolfgang Marquardt,et al.  Optimal column sequencing for multicomponent mixtures , 2008 .

[21]  Wolfgang Marquardt,et al.  Conceptual Design of Distillation Processes for Mixtures with Distillation Boundaries: I. Computational Assessment of Split Feasibility , 2011 .

[22]  F. B. Petlyuk,et al.  Distillation Theory and Its Application to Optimal Design of Separation Units: Index , 2004 .

[23]  Rafiqul Gani,et al.  A systematic synthesis framework for extractive distillation processes , 2008 .

[24]  Curtis H. Whitson,et al.  The negative flash , 1989 .

[25]  R. Reid,et al.  The Properties of Gases and Liquids , 1977 .

[26]  Michael F. Doherty,et al.  Design and synthesis of homogeneous azeotropic distillations. 3. The sequencing of columns for azeotropic and extractive distillations , 1985 .

[27]  Angelo Lucia,et al.  Distillation pinch points and more , 2008, Comput. Chem. Eng..

[28]  Gary J. Powers,et al.  Synthesis strategies for multicomponent separation systems with energy integration , 1974 .

[29]  Arthur W. Westerberg,et al.  A problem decomposition approach for the synthesis of complex separation processes with recycles , 1993 .

[30]  Josef Kallrath,et al.  Mixed Integer Optimization in the Chemical Process Industry: Experience, Potential and Future Perspectives , 2000 .

[31]  Wolfgang Marquardt,et al.  Design of Heat-Integrated Distillation Processes Using Shortcut Methods and Rigorous Optimization , 2009 .

[32]  Rafiqul Gani,et al.  A multi-step and multi-level approach for computer aided molecular design , 2000 .

[33]  Ping Zhang,et al.  Robust dynamic simulation of three-phase reactive batch distillation columns , 2004 .

[34]  Wolfgang Marquardt,et al.  Conceptual design of distillation-based hybrid separation processes. , 2013, Annual review of chemical and biomolecular engineering.

[35]  Wolfgang Marquardt,et al.  Näherungsverfahren für den konzeptionellen Entwurf und die thermodynamische Analyse von destillativen Trennprozessen , 2001 .

[36]  Sten Bay Jørgensen,et al.  A novel framework for simultaneous separation process and product design , 2004 .

[37]  Alfons Vogelpohl.  Die näherungsweise Berechnung der Rektifikation von Gemischen mit binären Azeotropen , 1974 .

[38]  R.W.H. Sargent,et al.  A functional approach to process synthesis and its application to distillation systems , 1998 .

[39]  G. Towler,et al.  Chapter 7 – Capital Cost Estimating , 2012 .

[40]  Jochen Büchs,et al.  Systematic Approach to Solvent Selection for Biphasic Systems with a Combination of COSMO‐RS and a Dynamic Modeling Tool , 2008 .

[41]  Angelo Lucia,et al.  Energy Efficient Hybrid Separation Processes , 2006 .

[42]  Michael F. Doherty,et al.  Geometric nonlinear analysis of multicomponent nonideal distillation: a simple computer-aided design procedure , 1993 .

[43]  Christianto Wibowo,et al.  Visualization of high‐dimensional phase diagrams of molecular and ionic mixtures , 2002 .

[44]  Oliver Stein,et al.  Continuous reformulations of discrete-continuous optimization problems , 2004, Comput. Chem. Eng..

[45]  M. Doherty,et al.  Design and synthesis of homogeneous azeotropic distillations. 1. Problem formulation for a single column , 1985 .

[46]  A. Underwood,et al.  Fractional Distillation of Multicomponent Mixtures , 1949 .

[47]  Michael F. Doherty,et al.  Geometric behavior and minimum flows for nonideal multicomponent distillation , 1990 .

[48]  J. W. Ponton,et al.  Foundations of Computer-aided Process Design: Edited by A.W. Westerberg and H.H. Chein CACHE Publication, 1042 pp., $133.25 , 1986 .

[49]  Michael L. Free.  Process Design Principles , 2013 .

[50]  Rafiqul Gani,et al.  MOLECULAR DESIGN OF SOLVENTS FOR LIQUID EXTRACTION BASED ON UNIFAC , 1983 .

[51]  W. D. Villiers,et al.  Navigate phase equilibria via residue curve maps , 2002 .

[52]  André Bardow,et al.  Continuous-Molecular Targeting for Integrated Solvent and Process Design , 2010 .

[53]  Stanislaw K. Wasylkiewicz,et al.  Distillation profiles in ternary heterogeneous mixtures with distillation boundaries , 2011 .

[54]  Michael F. Doherty,et al.  On the dynamics of distillation processes—I: The simple distillation of multicomponent non-reacting, homogeneous liquid mixtures , 1978 .

[55]  Wolfgang Marquardt,et al.  A Framework for the Systematic Design of Hybrid Separation Processes * * Supported by the Deutsche F , 2008 .

[56]  Michael F. Doherty,et al.  A new pressure-swing-distillation process for separating homogeneous azeotropic mixtures , 1992 .

[57]  Arthur Westerberg,et al.  A retrospective on design and process synthesis , 2004, Comput. Chem. Eng..

[58]  Megan Jobson,et al.  Recycle Selection for Homogeneous Azeotropic Distillation Sequences , 2005 .

[59]  Michael F. Malone,et al.  Boundary Modes in a Single Feed Distillation Column for the Separation of Azeotropic Mixtures , 1997 .

[60]  David Glasser,et al.  A new method of locating all pinch points in nonideal distillation systems, and its application to pinch point loci and distillation boundaries , 2011, Comput. Chem. Eng..

[61]  Wolfgang Marquardt,et al.  Conceptual design of distillation processes for mixtures with distillation boundaries. II. Optimization of recycle policies , 2011 .

[62]  Michael F. Malone,et al.  Conceptual design of distillation systems , 2001 .

[63]  Megan Jobson,et al.  Flowsheet synthesis and complex distillation column design for separating ternary heterogeneous azeotropic mixtures , 2011 .

[64]  J. Stichlmair,et al.  Synthesis and optimization of distillation sequences for the separation of azeotropic mixtures , 1995 .

[65]  James M. Douglas,et al.  A hierarchical decision procedure for process synthesis , 1985 .

[66]  S. Skogestad,et al.  Identification and analysis of possible splits for azeotropic mixtures—1. Method for column sections , 2011 .

[67]  Megan Jobson,et al.  Multicomponent homogeneous azeotropic distillation. 3. Column sequence synthesis. , 2001 .

[68]  Warren D. Seider,et al.  Journal review. Azeotropic distillation , 1996 .

[69]  J. Seader,et al.  Use of homotopy-continuation method in stability analysis of multiphase, reacting systems , 2000 .

[70]  Robert Leonard Kirkwood,et al.  PIP--PROCESS INVENTION PROCEDURE: A PROTOTYPE EXPERT SYSTEM FOR SYNTHESIZING CHEMICAL PROCESS FLOWSHEETS , 1988 .

[71]  E. W. Thiele,et al.  Graphical Design of Fractionating Columns , 1925 .

[72]  Andreas A. Linninger,et al.  Pinch Point Calculations and Its Implications on Robust Distillation Design , 2011 .

[73]  S. Glanz,et al.  Calculating minimum reflux of nonideal multicomponent distillation using eigenvalue theory , 1994 .

[74]  Eckhart Blass,et al.  Entwicklung verfahrenstechnischer Prozesse , 1997 .

[75]  Markku Hurme,et al.  Synthesis of separation processes by using case-based reasoning , 2001 .

[76]  Wolfgang Marquardt,et al.  Analysis and Conceptual Design of Ternary Heterogeneous Azeotropic Distillation Processes , 2002 .

[77]  James R. Fair,et al.  Separation system synthesis: a knowledge-based approach. 1. Liquid mixture separations , 1990 .

[78]  Diane Hildebrandt,et al.  Column Profile Maps. 1. Derivation and Interpretation , 2004 .

[79]  Sigurd Skogestad,et al.  Azeotropic phase equilibrium diagrams: a survey , 2003 .

[80]  M. Morari,et al.  Multiple Steady States in Homogeneous Azeotropic Distillation , 1993, 1993 American Control Conference.

[81]  Zhigang Lei,et al.  Extractive Distillation: A Review , 2003 .

[82]  E. Blass,et al.  Minimum reflux calculations for nonideal mixtures using the reversible distillation model , 1991 .

[83]  Andrzej Górak,et al.  Auslegung und Optimierung von hybriden Trennverfahren , 2004 .

[84]  Haibo Zhang,et al.  A review on global optimization methods for phase equilibrium modeling and calculations , 2011 .

[85]  Manfred Morari,et al.  The Curious Behavior of Homogeneous Azeotropic Distillation-Implications for Entrainer Selection , 1992 .

[86]  Wolfgang Marquardt,et al.  Shortcut methods for nonideal multicomponent distillation: 3. Extractive distillation columns , 2004 .

[87]  Rafiqul Gani,et al.  A New Decomposition-Based Computer-Aided Molecular/Mixture Design Methodology for the Design of Optimal Solvents and Solvent Mixtures , 2005 .

[88]  Attainable products for the vapour-liquid separation of homogeneous ternary mixtures , 1995 .

[89]  Megan Jobson,et al.  Shortcut design method for columns separating azeotropic mixtures , 2004 .

[90]  I. Grossmann,et al.  Optimal Design of Complex Distillation Columns Using Rigorous Tray-by-Tray Disjunctive Programming Models , 2000 .

[91]  Kai Sundmacher,et al.  Equilibrium and rate-based approaches to liquid-liquid phase splitting calculations , 2005, Comput. Chem. Eng..

[92]  Roger W. Thompson,et al.  Systematic synthesis of separation schemes , 1972 .

[93]  Michael F. Malone,et al.  Automatic screening of entrainers for homogeneous azeotropic distillation , 1991 .

[94]  Lorenz T. Biegler,et al.  Distributed stream method for tray optimization , 2002 .

[95]  Manfred Morari,et al.  Homogeneous azeotropic distillation: Comparing entrainers , 1991 .

[96]  Francisco J. L. Castillo,et al.  Homogeneous Azeotropic Distillation. 2. Design Procedure for Sequences of Columns , 1998 .

[97]  Michael F. Malone,et al.  Nonideal Multicomponent Distillation: Use of Bifurcation Theory for Design , 1991 .

[98]  James R. Fair,et al.  Distillation: Principles and Practices , 1998 .

[99]  B. Cairns,et al.  Multicomponent three-phase azeotropic distillation. 2. Phase-stability and phase-splitting algorithms , 1990 .

[100]  Andreas A. Linninger,et al.  Temperature Collocation Algorithm for Fast and Robust Distillation Design , 2004 .

[101]  Francisco J. L. Castillo,et al.  Homogeneous Azeotropic Distillation. 1. Design Procedure for Single-Feed Columns at Nontotal Reflux , 1998 .

[102]  A. W. Westerberg,et al.  The product composition regions of single-feed azeotropic distillation columns , 1992 .

[103]  James R. Fair,et al.  Separation system synthesis: a knowledge-based approach. 2. Gas/vapor mixtures , 1992 .

[104]  Wolfgang Marquardt,et al.  Shortcut methods for nonideal multicomponent distillation: 2. Complex columns , 1998 .

[105]  L. T. Fan,et al.  Graph-theoretic approach to process synthesis: Polynomial algorithm for maximal structure generation , 1993 .

[106]  Robin Smith,et al.  Synthesis of distillation sequences for separating multicomponent azeotropic mixtures , 2002 .

[107]  Arthur W. Westerberg,et al.  The product composition regions of azeotropic distillation columns. 2. Separability in two-feed columns and entrainer selection , 1993 .

[108]  Lechoslaw J. Krolikowski,et al.  Determination of distillation regions for non‐ideal ternary mixtures , 2006 .

[109]  Ignacio E. Grossmann,et al.  Optimal feed locations and number of trays for distillation columns with multiple feeds , 1993 .

[110]  Megan Jobson,et al.  Multicomponent homogeneous azeotropic distillation. 2. Column design , 2001 .

[111]  Michael F. Doherty,et al.  Minimum entrainer flows for extractive distillation: A bifurcation theoretic approach , 1994 .

[112]  Johann Stichlmair,et al.  Minimum reflux and minimum reboil in ternary distillation , 1993 .

[113]  Wolfgang Marquardt,et al.  Efficient optimization-based design for the separation of heterogeneous azeotropic mixtures , 2015, Comput. Chem. Eng..

[114]  Megan Jobson,et al.  Multicomponent homogeneous azeotropic distillation 1. Assessing product feasibility , 2001 .

[115]  Stanislaw K. Wasylkiewicz,et al.  Synthesis and design of heterogeneous separation systems with recycle streams , 2003 .

[116]  Michael F. Doherty,et al.  Design and synthesis of heterogeneous azeotropic distillations—I. Heterogeneous phase diagrams , 1990 .

[117]  Rafiqul Gani,et al.  SEPARATION PROCESS DESIGN AND SYNTHESIS BASED ON THERMODYNAMIC INSIGHTS , 1995 .

[118]  Michael F. Doherty,et al.  Design and minimum reflux for heterogeneous azeotropic distillation columns , 1989 .

[119]  Rakesh Agrawal,et al.  A matrix method for multicomponent distillation sequences , 2009 .

[120]  James M. Douglas,et al.  Conceptual Design of Chemical Processes , 1988 .

[121]  Wolfgang Marquardt,et al.  Shortcut-based design of multicomponent heteroazeotropic distillation , 2011 .

[122]  S. Skogestad,et al.  Identification and analysis of possible splits for azeotropic mixtures. 2. Method for simple columns , 2012 .

[123]  Angelo Lucia,et al.  A two‐level distillation design method , 2008 .

[124]  W. Marquardt,et al.  Efficient Optimization-Based Design of Distillation Columns for Homogenous Azeotropic Mixtures , 2006 .