Bioactive Peptides from African Yam (AVIAIMF and GPADPF) and Taro (NGDF and NGNW) Reveal Multifunctional Antidiabetic Effects Using Biochemical and Cellular Models

[1]  J. Hsu,et al.  Characteristics of Food Protein-Derived Antidiabetic Bioactive Peptides: A Literature Update , 2021, International journal of molecular sciences.

[2]  Ranjit Vijayan,et al.  Bioactive Peptides as Potential Nutraceuticals for Diabetes Therapy: A Comprehensive Review , 2021, International journal of molecular sciences.

[3]  A. Nakamura,et al.  Advanced Glycation End Products and Oxidative Stress in a Hyperglycaemic Environment , 2021, Fundamentals of Glycosylation [Working Title].

[4]  Haipo Yuan,et al.  Nitric Oxide Mediates Inflammation in Type II Diabetes Mellitus through the PPARγ/eNOS Signaling Pathway , 2020, PPAR research.

[5]  Putcha Petsantad,et al.  The antioxidant potential of peptides obtained from the spotted babylon snail (Babylonia areolata) in treating human colon adenocarcinoma (Caco-2) cells , 2020, RSC advances.

[6]  M. Bester,et al.  The dipeptidyl peptidase IV inhibitory activity and multifunctional antidiabetic properties of SQSPA: Structure - Activity analysis evaluated with alanine scanning. , 2020, International journal of biological macromolecules.

[7]  Yang Tian,et al.  Identification of Potential Dipeptidyl Peptidase (DPP)-IV Inhibitors among Moringa oleifera Phytochemicals by Virtual Screening, Molecular Docking Analysis, ADME/T-Based Prediction, and In Vitro Analyses , 2020, Molecules.

[8]  Chibuike C. Udenigwe,et al.  Considering food matrix and gastrointestinal effects in enhancing bioactive peptide absorption and bioavailability , 2020 .

[9]  Gopal L. Khatik,et al.  An insight of Alpha-amylase inhibitors as a Valuable Tool in the Management of Type 2 Diabetes Mellitus. , 2020, Current diabetes reviews.

[10]  A. Neitz,et al.  New Antidiabetic Targets of α-Glucosidase Inhibitory Peptides, SVPA, SEPA, STYV and STY: Inhibitory Effects on Dipeptidyl Peptidase-IV and Lipid Accumulation in 3T3-L1 Differentiated Adipocytes with Scavenging Activities Against Methylglyoxal and Reactive Oxygen Species , 2019, International Journal of Peptide Research and Therapeutics.

[11]  Nilima S. Bangar,et al.  Comparative study of different glycating agents on human plasma and vascular cells , 2019, Molecular Biology Reports.

[12]  Y. Kim,et al.  Phyllanthus emblica fruit extract attenuates lipid metabolism in 3T3-L1 adipocytes via activating apoptosis mediated cell death. , 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[13]  K. Kalia,et al.  Plant-Derived Bioactive Peptides: A Treatment to Cure Diabetes , 2019, International Journal of Peptide Research and Therapeutics.

[14]  B. Ahrén DPP-4 Inhibition and the Path to Clinical Proof , 2019, Front. Endocrinol..

[15]  C. Lammi,et al.  Multifunctional peptides for the prevention of cardiovascular disease: A new concept in the area of bioactive food-derived peptides , 2019, Journal of Functional Foods.

[16]  Hye-Kyeong Kim,et al.  Fucoidan from Undaria pinnatifida has anti-diabetic effects by stimulation of glucose uptake and reduction of basal lipolysis in 3T3-L1 adipocytes. , 2019, Nutrition research.

[17]  A. Neitz,et al.  Multiple antidiabetic effects of three α-glucosidase inhibitory peptides, PFP, YPL and YPG: Dipeptidyl peptidase-IV inhibition, suppression of lipid accumulation in differentiated 3T3-L1 adipocytes and scavenging activity on methylglyoxal. , 2019, International journal of biological macromolecules.

[18]  Hao Wu,et al.  Discovery of Food-Derived Dipeptidyl Peptidase IV Inhibitory Peptides: A Review , 2019, International journal of molecular sciences.

[19]  B. Murray,et al.  Identification of angiotensin converting enzyme and dipeptidyl peptidase-IV inhibitory peptides derived from oilseed proteins using two integrated bioinformatic approaches. , 2019, Food research international.

[20]  A. Nongonierma,et al.  Features of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from dietary proteins. , 2019, Journal of food biochemistry.

[21]  A. Neitz,et al.  Tuber Storage Proteins as Potential Precursors of Bioactive Peptides: An In Silico Analysis , 2019, International Journal of Peptide Research and Therapeutics.

[22]  G. Jacobson,et al.  Citrus bioflavonoids dipeptidyl peptidase-4 inhibition compared with gliptin antidiabetic medications. , 2018, Biochemical and biophysical research communications.

[23]  Bo Wang,et al.  Charge and hydrophobicity of casein peptides influence transepithelial transport and bioavailability. , 2018, Food chemistry.

[24]  Aubry K. Miller,et al.  Elevated Levels of the Reactive Metabolite Methylglyoxal Recapitulate Progression of Type 2 Diabetes. , 2018, Cell metabolism.

[25]  J. Shaw,et al.  IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045. , 2018, Diabetes research and clinical practice.

[26]  Erin E. Mulvihill Dipeptidyl peptidase inhibitor therapy in type 2 diabetes: Control of the incretin axis and regulation of postprandial glucose and lipid metabolism , 2018, Peptides.

[27]  S. Varshney,et al.  Aegeline inspired synthesis of novel amino alcohol and thiazolidinedione hybrids with antiadipogenic activity in 3T3-L1 cells. , 2018, European journal of medicinal chemistry.

[28]  F. Guimarães,et al.  A novel peptide that improves metabolic parameters without adverse central nervous system effects , 2017, Scientific Reports.

[29]  A. Alhassan,et al.  Flavonoids from Tetracera indica Merr. induce adipogenesis and exert glucose uptake activities in 3T3-L1 adipocyte cells , 2017, BMC Complementary and Alternative Medicine.

[30]  H. Shimano,et al.  Comparative Binding Analysis of Dipeptidyl Peptidase IV (DPP-4) with Antidiabetic Drugs – An Ab Initio Fragment Molecular Orbital Study , 2016, PloS one.

[31]  Q. Saquib,et al.  In-Vitro dual inhibition of protein glycation, and oxidation by some Arabian plants , 2016, BMC Complementary and Alternative Medicine.

[32]  E. Li-Chan,et al.  Food-derived dipeptidyl-peptidase IV inhibitors as a potential approach for glycemic regulation : current knowledge and future research considerations , 2016 .

[33]  H. Arimochi,et al.  Differentiation of preadipocytes and mature adipocytes requires PSMB8 , 2016, Scientific Reports.

[34]  P. Mayer,et al.  Metabolic role of dipeptidyl peptidase 4 (DPP4) in primary human (pre)adipocytes , 2016, Scientific Reports.

[35]  H. Lee,et al.  Hypoglycaemic effects of functional tri-peptides from silk in differentiated adipocytes and streptozotocin-induced diabetic mice. , 2016, Journal of the science of food and agriculture.

[36]  S. Rajagopalan,et al.  Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials , 2015, Journal of diabetes research.

[37]  Bin Wang,et al.  Influence of Amino Acid Compositions and Peptide Profiles on Antioxidant Capacities of Two Protein Hydrolysates from Skipjack Tuna (Katsuwonus pelamis) Dark Muscle , 2015, Marine drugs.

[38]  Hilma Eiðsdóttir Bakken,et al.  Preventive effect of Nile tilapia hydrolysate against oxidative damage of HepG2 cells and DNA mediated by H2O2 and AAPH , 2015, Journal of Food Science and Technology.

[39]  D. Matthews,et al.  Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a Position Statement of the American Diabetes Association and the European Association for the Study of Diabetes , 2015, Diabetologia.

[40]  B. Ahrén,et al.  Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors , 2014, Diabetes.

[41]  Babij Konrad,et al.  The Evaluation of Dipeptidyl Peptidase (DPP)-IV, α-Glucosidase and Angiotensin Converting Enzyme (ACE) Inhibitory Activities of Whey Proteins Hydrolyzed with Serine Protease Isolated from Asian Pumpkin (Cucurbita ficifolia) , 2014, International Journal of Peptide Research and Therapeutics.

[42]  J. Shaw,et al.  Global estimates of diabetes prevalence for 2013 and projections for 2035. , 2014, Diabetes Research and Clinical Practice.

[43]  A. Vulpetti,et al.  Comparability of Mixed IC50 Data – A Statistical Analysis , 2013, PloS one.

[44]  S. Yamagishi Advanced Glycation End-Products , 2013 .

[45]  E. Li-Chan,et al.  Dipeptidyl peptidase-IV inhibitory activity of dairy protein hydrolysates , 2012 .

[46]  K. Kazakos,et al.  Incretin effect: GLP-1, GIP, DPP4. , 2011, Diabetes research and clinical practice.

[47]  A. Avogaro,et al.  Endothelial Dysfunction in Diabetes , 2011, Diabetes Care.

[48]  A. Avogaro,et al.  Endothelial Dysfunction in Diabetes The role of reparatory mechanisms , 2011 .

[49]  Y. Zou,et al.  Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products , 2008, Circulation research.

[50]  Daigo Abe,et al.  Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes. , 2007, Biochemical and biophysical research communications.

[51]  L. Liaudet,et al.  Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.

[52]  C. van Weel,et al.  Alpha-glucosidase inhibitors for patients with type 2 diabetes: results from a Cochrane systematic review and meta-analysis. , 2005, Diabetes care.

[53]  Dejian Huang,et al.  Analysis of antioxidant activities of common vegetables employing oxygen radical absorbance capacity (ORAC) and ferric reducing antioxidant power (FRAP) assays: a comparative study. , 2002, Journal of agricultural and food chemistry.

[54]  M. Brownlee Biochemistry and molecular cell biology of diabetic complications , 2001, Nature.