Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.

[1]  M. Gladwin,et al.  Measurement of circulating nitrite and S-nitrosothiols by reductive chemiluminescence. , 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[2]  M. Gladwin,et al.  Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis , 2006, Nature chemical biology.

[3]  M. Gladwin,et al.  Inhaled nitric oxide decreases infarction size and improves left ventricular function in a murine model of myocardial ischemia-reperfusion injury. , 2006, American journal of physiology. Heart and circulatory physiology.

[4]  X. Waintraub,et al.  Isoflurane Inhaled at the Onset of Reperfusion Potentiates the Cardioprotective Effect of Ischemic Postconditioning Through a NO-dependent Mechanism , 2006, Journal of cardiovascular pharmacology.

[5]  Martin Feelisch,et al.  Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues , 2005, Nature chemical biology.

[6]  J. López-Ramos,et al.  Evidence of a decrease in nitric oxide-storage molecules following acute hypoxia and/or hypobaria, by means of chemiluminescence analysis. , 2005, Nitric oxide : biology and chemistry.

[7]  D. Yellon,et al.  Myocardial postconditioning: reperfusion injury revisited. , 2005, American journal of physiology. Heart and circulatory physiology.

[8]  Mark R. Duranski,et al.  Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. , 2005, The Journal of clinical investigation.

[9]  Q. Feng,et al.  Modulation of apoptosis by nitric oxide: implications in myocardial ischemia and heart failure. , 2005, Pharmacology & therapeutics.

[10]  T. Meinertz,et al.  Myeloperoxidase enhances nitric oxide catabolism during myocardial ischemia and reperfusion. , 2004, Free radical biology & medicine.

[11]  R. Bolli,et al.  Myocardial Protection at a Crossroads: The Need for Translation Into Clinical Therapy , 2004, Circulation research.

[12]  G. Ambrosio,et al.  The multi-faceted behavior of nitric oxide in vascular "inflammation": catchy terminology or true phenomenon? , 2004, Cardiovascular research.

[13]  Xiaoping Liu,et al.  Characterization of the Effects of Oxygen on Xanthine Oxidase-mediated Nitric Oxide Formation* , 2004, Journal of Biological Chemistry.

[14]  J. Zweier,et al.  Nitrosyl-Heme Complexes Are Formed in the Ischemic Heart , 2004, Journal of Biological Chemistry.

[15]  P. Kubes,et al.  Enhanced S-Nitroso-Albumin Formation From Inhaled NO During Ischemia/Reperfusion , 2004, Circulation research.

[16]  M. Fujii,et al.  Nicorandil versus isosorbide dinitrate as adjunctive treatment to direct balloon angioplasty in acute myocardial infarction , 2004, Heart.

[17]  M. Gladwin,et al.  Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation , 2003, Nature Medicine.

[18]  P. Boekstegers,et al.  VEGF165 transfection decreases postischemic NF‐κB‐dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation , 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  M. Gladwin,et al.  Methodologies for the Sensitive and Specific Measurement of S -nitrosothiols, Iron-nitrosyls, and Nitrite in Biological Samples , 2003, Free radical research.

[20]  H. Drexler,et al.  Regulation of Cardiac Remodeling by Nitric Oxide: Focus on Cardiac Myocyte Hypertrophy and Apoptosis , 2002, Heart Failure Reviews.

[21]  R. de Caterina,et al.  Inhaled nitric oxide: more than a selective pulmonary vasodilator , 2002, European journal of clinical investigation.

[22]  Chunxiang Zhang,et al.  Myeloperoxidase, a Leukocyte-Derived Vascular NO Oxidase , 2002, Science.

[23]  George Dangas,et al.  Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction. , 2002, Journal of the American College of Cardiology.

[24]  M. Gladwin,et al.  Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery. , 2001, The Journal of clinical investigation.

[25]  L. Becker,et al.  Neutrophils are primary source of O2 radicals during reperfusion after prolonged myocardial ischemia. , 2001, American journal of physiology. Heart and circulatory physiology.

[26]  P. Sjöquist,et al.  Relationship between ischaemic time and ischaemia/reperfusion injury in isolated Langendorff-perfused mouse hearts. , 2001, Acta physiologica Scandinavica.

[27]  T. Higenbottam,et al.  A therapeutic role for chronic inhaled nitric oxide? , 2000, The Lancet.

[28]  Katherine C. Wu,et al.  Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction. , 2000, Circulation.

[29]  S. Mordon,et al.  Inhaled NO reduces leukocyte-endothelial cell interactions and myocardial dysfunction in endotoxemic rats. , 2000, American journal of physiology. Heart and circulatory physiology.

[30]  R. Testa,et al.  Beneficial effects of intracoronary adenosine as an adjunct to primary angioplasty in acute myocardial infarction. , 2000, Circulation.

[31]  D. Granger,et al.  Pathophysiology of ischaemia–reperfusion injury , 2000, The Journal of pathology.

[32]  C M Gibson,et al.  Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs. , 2000, Circulation.

[33]  A. Lefer,et al.  Mechanisms of cardioprotection by peroxynitrite in myocardial ischemia and reperfusion injury. , 1998, American journal of physiology. Heart and circulatory physiology.

[34]  H. Suryapranata,et al.  Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Zwolle Myocardial Infarction Study Group. , 1998, Circulation.

[35]  P. Kubes,et al.  Inhaled NO as a viable antiadhesive therapy for ischemia/reperfusion injury of distal microvascular beds. , 1998, The Journal of clinical investigation.

[36]  L. Becker,et al.  Apoptosis is prevented by administration of superoxide dismutase in dogs with reperfused myocardial infarction , 1998, Basic Research in Cardiology.

[37]  D. Collen,et al.  Nitric oxide inhalation inhibits platelet aggregation and platelet-mediated pulmonary thrombosis in rats. , 1997, Circulation research.

[38]  J. Zweier,et al.  Measurement of Nitric Oxide and Peroxynitrite Generation in the Postischemic Heart , 1996, The Journal of Biological Chemistry.

[39]  H. Gold,et al.  Inhaled nitric oxide increases coronary artery patency after thrombolysis. , 1996, Circulation.

[40]  Jesse D. Roberts,et al.  Chronic inhalation of nitric oxide inhibits neointimal formation after balloon-induced arterial injury. , 1996, Circulation research.

[41]  J. Zweier,et al.  Enzyme-independent formation of nitric oxide in biological tissues , 1995, Nature Medicine.

[42]  C. Schade-Brittinger,et al.  Comparative study on the effects of intracoronary nicorandil and nitroglycerin in ischaemic, reperfused porcine hearts. , 1995, European heart journal.

[43]  J. Perrard,et al.  Molecular evidence for induction of intracellular adhesion molecule-1 in the viable border zone associated with ischemia-reperfusion injury of the dog heart. , 1994, Circulation.

[44]  D. Lefer,et al.  Antineutrophil and Myocardial Protecting Actions of a Novel Nitric Oxide Donor After Acute Myocardial Ischemia and Reperfusion in Dogs , 1993, Circulation.

[45]  J. Zweier,et al.  Cardioprotective Actions of a Monoclonal Antibody Against CD‐18 in Myocardial Ischemia‐Reperfusion Injury , 1993, Circulation.

[46]  E. Ohman,et al.  Temporal creatine kinase curves in acute myocardial infarction. Implications of a good empiric fit with the log-normal function. , 1993, American journal of clinical pathology.

[47]  R W Glenny,et al.  Validation of fluorescent-labeled microspheres for measurement of regional organ perfusion. , 1993, Journal of applied physiology.

[48]  M. Condorelli,et al.  Endothelium-derived relaxing factor modulates platelet aggregation in an in vivo model of recurrent platelet activation. , 1992, Circulation research.

[49]  L. Becker,et al.  Progressive impairment of regional myocardial perfusion after initial restoration of postischemic blood flow. , 1989, Circulation.

[50]  U. Elkayam,et al.  Hemodynamic effects of intravenous isosorbide dinitrate and nitroglycerine in acute myocardial infarction and elevated pulmonary artery wedge pressure. , 1987, Chest.

[51]  K. Mullane,et al.  Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. , 1985, Journal of pharmacological methods.

[52]  B. Jugdutt Use of nitroglycerin for the treatment of acute myocardial infarction , 2005, Heart and Vessels.

[53]  J. Zweier,et al.  Does Lethal Myocardial Reperfusion Injury Exist? , 2004, Journal of Thrombosis and Thrombolysis.

[54]  F. Epstein,et al.  Infarct involution and improved function during healing of acute myocardial infarction: the role of microvascular obstruction. , 2004, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[55]  GISSI-3: effects of lisinopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction. Gruppo Italiano per lo Studio della Sopravvivenza nell'infarto Miocardico. , 1994, Lancet.