Self‐reported pain sensitivity: Lack of correlation with pain threshold and tolerance

Many recent studies and several reviews have highlighted the potential clinical applications of experimental pain testing (e.g., for predicting post‐surgical pain, treatment responsiveness, etc.). However, the implementation of quantitative sensory testing of pain sensitivity on a broad scale is limited by requirements of time, equipment, and expertise, and their associated costs. One reasonable question is whether one can obtain, via self‐report, a valid index of an individual's pain sensitivity and pain tolerance. We analyzed data from a large number of subjects (n=505) who had undergone standardized thermal pain testing, and found that while higher self‐reported pain sensitivity was associated with higher scores on a measure of anxiety, no relationship was observed between subjects’ self‐report of pain sensitivity and subjects’ actual pain threshold or tolerance. These findings suggest that circumventing psychophysical pain testing by assessing individuals’ self‐reported pain sensitivity is unlikely to be a useful strategy.

[1]  Daniel J Clauw,et al.  Increased pain sensitivity in fibromyalgia: effects of stimulus type and mode of presentation , 2003, Pain.

[2]  Robert C. Coghill,et al.  Neural correlates of interindividual differences in the subjective experience of pain , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[3]  S. Shiffman,et al.  Patient compliance with paper and electronic diaries. , 2003, Controlled clinical trials.

[4]  W. Maixner,et al.  Associations among four modalities of experimental pain in women. , 2005, The journal of pain : official journal of the American Pain Society.

[5]  Timothy T Houle,et al.  Multifactorial Preoperative Predictors for Postcesarean Section Pain and Analgesic Requirement , 2006, Anesthesiology.

[6]  G. Rollman,et al.  Generalized hypervigilance in fibromyalgia: evidence of perceptual amplification , 1996, PAIN®.

[7]  Robert J Glynn,et al.  How well do patients report noncompliance with antihypertensive medications?: a comparison of self‐report versus filled prescriptions , 2004, Pharmacoepidemiology and drug safety.

[8]  Dieter Kleinböhl,et al.  Psychophysical measures of sensitization to tonic heat discriminate chronic pain patients , 1999, Pain.

[9]  W. Maixner,et al.  Genetic basis for individual variations in pain perception and the development of a chronic pain condition. , 2005, Human molecular genetics.

[10]  R. Edwards,et al.  Individual differences in endogenous pain modulation as a risk factor for chronic pain , 2005, Neurology.

[11]  R. Fillingim,et al.  Individual differences in pain responses , 2005, Current rheumatology reports.

[12]  R. Fillingim,et al.  Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain , 2004, Pain.

[13]  Bonica Jj History of pain concepts and pain therapy. , 1991 .

[14]  Joshua A. Bueller,et al.  COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor , 2003, Science.

[15]  R. Fillingim,et al.  Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adults , 2003, Pain.

[16]  D. Yarnitsky,et al.  Postcesarean Section Pain Prediction by Preoperative Experimental Pain Assessment , 2003, Anesthesiology.

[17]  R. Fillingim,et al.  Influences of gender role and anxiety on sex differences in temporal summation of pain. , 2004, The journal of pain : official journal of the American Pain Society.

[18]  M. Max,et al.  Basal Heat Pain Thresholds Predict Opioid Analgesia in Patients with Postherpetic Neuralgia , 2006, Anesthesiology.

[19]  R. Fillingim,et al.  Ethnic differences in responses to multiple experimental pain stimuli , 2005, Pain.

[20]  Robert R. Edwards,et al.  Quantitative assessment of experimental pain perception: multiple domains of clinical relevance , 2005, Pain.

[21]  Roger B. Fillingim,et al.  Cluster analysis of multiple experimental pain modalities , 2005, Pain.

[22]  H. Doll,et al.  Heightened accuracy of self-reported weight in bulimia nervosa: a useful cognitive "distortion". , 1998, The International journal of eating disorders.

[23]  R. Fillingim,et al.  Sex differences in the perception of noxious experimental stimuli: a meta-analysis , 1998, Pain.

[24]  D. Yarnitsky,et al.  Association between quantitative sensory testing, treatment choice, and subsequent pain reduction in vulvar vestibulitis syndrome. , 2004, The journal of pain : official journal of the American Pain Society.

[25]  R. Fillingim,et al.  Ethnic differences in thermal pain responses. , 1999, Psychosomatic medicine.

[26]  G. Carli,et al.  Reactivity to superficial and deep stimuli in patients with chronic musculoskeletal pain , 2002, Pain.

[27]  R. Fillingim,et al.  Age-associated differences in responses to noxious stimuli. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.