Binding between Prion Protein and Aβ Oligomers Contributes to the Pathogenesis of Alzheimer’s Disease
暂无分享,去创建一个
Taolei Sun | Ming Shao | Chaoyang Li | Chang Kong | Run Shi | Shanshan Gao | Lili Cai | Zhenxing Gao | Huan Li | Hao Xie
[1] C. Becker,et al. Prion protein—Semisynthetic prion protein (PrP) variants with posttranslational modifications , 2019, Journal of peptide science : an official publication of the European Peptide Society.
[2] M. Luo,et al. Prion dimer is heterogenous and is modulated by multiple negative and positive motifs. , 2019, Biochemical and biophysical research communications.
[3] D. Raha,et al. Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors , 2019, Science Advances.
[4] Jie Chen,et al. Glycosylation Significantly Inhibits the Aggregation of Human Prion Protein and Decreases Its Cytotoxicity , 2018, Scientific Reports.
[5] Joanne Rich,et al. Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups , 2018, bioRxiv.
[6] Y. Fang,et al. Genetic association of the cytochrome c oxidase-related genes with Alzheimer’s disease in Han Chinese , 2018, Neuropsychopharmacology.
[7] Nathan D. Price,et al. Summary of the 11th International Conference on Human Herpesviruses‐6A, ‐6B, and ‐7 , 2018, Neuron.
[8] J. H. Viles,et al. Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease , 2018, The Journal of Biological Chemistry.
[9] D. Stephan,et al. An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk , 2018, Neurobiology of Aging.
[10] S. Prusiner,et al. β-Amyloid Prions and the Pathobiology of Alzheimer's Disease. , 2018, Cold Spring Harbor perspectives in medicine.
[11] Chaoyang Li. Prion protein is required for tumor necrosis factor alpha (TNFα)‐triggered nuclear factor kappa B (NF‐κB) signaling and cytokine production. , 2018 .
[12] J. Hardy,et al. Alzheimer's disease , 2018, European journal of neurology.
[13] J. Leszek,et al. The Infectious Etiology of Alzheimer’s Disease , 2017, Current neuropharmacology.
[14] Jun Wang,et al. Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production , 2017, The Journal of Biological Chemistry.
[15] R. Itzhaki. Herpes simplex virus type 1 and Alzheimer's disease: possible mechanisms and signposts , 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[16] L. Lannfelt,et al. Decreased HHV-6 IgG in Alzheimer’s Disease , 2017, Front. Neurol..
[17] O. Uthman. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. , 2016, Lancet.
[18] Ying Zhu,et al. Glycan-deficient PrP stimulates VEGFR2 signaling via glycosaminoglycan. , 2016, Cellular signalling.
[19] C. Betzel,et al. Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta‐mediated neurotoxicity , 2016, Journal of neurochemistry.
[20] J. Schott. Infection, inflammation and Alzheimer's disease , 2015, European journal of neurology.
[21] A. Hill,et al. The prion protein constitutively controls neuronal store-operated Ca2+ entry through Fyn kinase , 2015, Front. Cell. Neurosci..
[22] J. Gilthorpe,et al. Reactivated herpes simplex infection increases the risk of Alzheimer's disease , 2015, Alzheimer's & Dementia.
[23] A. Vortmeyer,et al. Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models* , 2015, The Journal of Biological Chemistry.
[24] P. Wolf,et al. Gender and incidence of dementia in the Framingham Heart Study from mid-adult life , 2015, Alzheimer's & Dementia.
[25] C. Dobson,et al. Single-Molecule Imaging Reveals that Small Amyloid-β1–42 Oligomers Interact with the Cellular Prion Protein (PrPC) , 2014, ChemBioChem.
[26] D. Dunstan,et al. A brief overview of amyloids and Alzheimer's disease , 2014, Protein science : a publication of the Protein Society.
[27] S. Strittmatter,et al. Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)* , 2014, The Journal of Biological Chemistry.
[28] S. Prusiner,et al. Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients , 2014, Proceedings of the National Academy of Sciences.
[29] S. Prusiner,et al. Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice , 2014, Proceedings of the National Academy of Sciences.
[30] L. Spinney. Alzheimer's disease: The forgetting gene , 2014, Nature.
[31] Lihua Zhang,et al. Prion protein and cancers. , 2014, Acta biochimica et biophysica Sinica.
[32] Lifeng Yang,et al. Prion Protein Participates in the Protection of Mice from Lipopolysaccharide Infection by Regulating the Inflammatory Process , 2014, Journal of Molecular Neuroscience.
[33] C. Porro,et al. Biological role of Toll-like receptor-4 in the brain , 2014, Journal of Neuroimmunology.
[34] H. Schlüter,et al. High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease. , 2014, Brain : a journal of neurology.
[35] E. Masliah,et al. Herpes virus in Alzheimer's disease: relation to progression of the disease , 2014, Neurobiology of Aging.
[36] Ottavio Arancio,et al. Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors , 2014, PloS one.
[37] P. Vemuri,et al. Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences , 2014, Clinical epidemiology.
[38] Nick C Fox,et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.
[39] A. Vortmeyer,et al. Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein , 2013, Neuron.
[40] Peter R Schofield,et al. The Genetics of Dementia , 2013 .
[41] Bin Zhang,et al. Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons , 2013, Cell.
[42] J. Weuve,et al. Alzheimer disease in the United States (2010–2050) estimated using the 2010 census , 2013, Neurology.
[43] N. Hooper,et al. Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1* , 2013, The Journal of Biological Chemistry.
[44] Cornelia M. Wilson,et al. Tau protein kinases: Involvement in Alzheimer's disease , 2013, Ageing Research Reviews.
[45] M. Gobbi,et al. An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicity in Vivo* , 2013, The Journal of Biological Chemistry.
[46] Deming Zhao,et al. Cellular Prion Protein Participates in the Regulation of Inflammatory Response and Apoptosis in BV2 Microglia During Infection with Mycobacterium bovis , 2013, Journal of Molecular Neuroscience.
[47] J. H. Viles,et al. The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[48] D. Bennett,et al. The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease , 2012, The Journal of Neuroscience.
[49] Thomas C. Südhof,et al. Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities , 2012, The Journal of Neuroscience.
[50] R. Tanzi. The genetics of Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.
[51] A. Vortmeyer,et al. Alzheimer Amyloid-β Oligomer Bound to Post-Synaptic Prion Protein Activates Fyn to Impair Neurons , 2012, Nature Neuroscience.
[52] B. Riveau,et al. Requirement of cellular prion protein for intestinal barrier function and mislocalization in patients with inflammatory bowel disease. , 2012, Gastroenterology.
[53] Anne M. Remes,et al. Molecular Genetic Analysis of the APP, PSEN1, and PSEN2 Genes in Finnish Patients With Early-onset Alzheimer Disease and Frontotemporal Lobar Degeneration , 2012, Alzheimer disease and associated disorders.
[54] Stephen J. DeArmond,et al. Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions , 2012, Proceedings of the National Academy of Sciences.
[55] R. Tanzi,et al. Role of common and rare APP DNA sequence variants in Alzheimer disease , 2012, Neurology.
[56] Wei Yang,et al. Air Pollution, Oxidative Stress, and Alzheimer's Disease , 2012, Journal of environmental and public health.
[57] Guojun Bu,et al. Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. , 2012, Cold Spring Harbor perspectives in medicine.
[58] A. Nicot,et al. Exacerbation of experimental autoimmune encephalomyelitis in prion protein (PrPc)-null mice: evidence for a critical role of the central nervous system , 2012, Journal of Neuroinflammation.
[59] S. Lipton,et al. Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-d-aspartate receptors , 2012, Proceedings of the National Academy of Sciences.
[60] Stefan F. T. Weiss,et al. Global Alzheimer Research Summit , 2012, Prion.
[61] Alun Williams,et al. Amyloid-β-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins , 2011, The Journal of Biological Chemistry.
[62] Richard Mayeux,et al. Genetic counseling and testing for Alzheimer disease: Joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors , 2011, Genetics in Medicine.
[63] L. Cendron,et al. Aluminum, copper, iron and zinc differentially alter amyloid-Aβ(1-42) aggregation and toxicity. , 2011, The international journal of biochemistry & cell biology.
[64] M. Hoch,et al. Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease , 2011, The EMBO journal.
[65] M. Rowan,et al. Alzheimer's Disease Brain-Derived Amyloid-β-Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein , 2011, The Journal of Neuroscience.
[66] Anne Corbett,et al. Alzheimer's disease , 2011, The Lancet.
[67] Chengjie Xiong,et al. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease , 2011, Alzheimer's Research & Therapy.
[68] S. Faraone,et al. Review Article: Genetics of Alzheimer Disease , 2010, Journal of geriatric psychiatry and neurology.
[69] S. Strittmatter,et al. Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse , 2010, BMC Neuroscience.
[70] Jason J. Corneveaux,et al. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. , 2010, Human molecular genetics.
[71] V. Pankratz,et al. Replication of CLU, CR1, and PICALM associations with alzheimer disease. , 2010, Archives of neurology.
[72] J. Falsig,et al. Prion protein and Aβ-related synaptic toxicity impairment , 2010, EMBO molecular medicine.
[73] W. Surewicz,et al. Interaction between Human Prion Protein and Amyloid-β (Aβ) Oligomers , 2010, The Journal of Biological Chemistry.
[74] S. Strittmatter,et al. Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein , 2010, The Journal of Neuroscience.
[75] K. Jellinger,et al. Prevalence of dementia disorders in the oldest-old: an autopsy study , 2010, Acta Neuropathologica.
[76] T. Zako,et al. Amyloid oligomers: formation and toxicity of Aβ oligomers , 2010, The FEBS journal.
[77] L. Stitz,et al. Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling , 2010, Brain : a journal of neurology.
[78] C. Jack,et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade , 2010, The Lancet Neurology.
[79] M. Gobbi,et al. Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein , 2010, Proceedings of the National Academy of Sciences.
[80] C. Glabe,et al. Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction , 2009, Neurobiology of Disease.
[81] W. M. van der Flier,et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. , 2009, JAMA.
[82] P. Paoli,et al. PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin‐1 in the signal transduction pathway , 2009, Journal of neurochemistry.
[83] S. Sensi,et al. Alzheimer's disease, metal ions and metal homeostatic therapy. , 2009, Trends in pharmacological sciences.
[84] G. Zamponi. Faculty Opinions recommendation of Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. , 2009 .
[85] John W. Gilbert,et al. Cellular Prion Protein Mediates Impairment of Synaptic Plasticity by Amyloid-β Oligomers , 2009, Nature.
[86] F. Jirik,et al. Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis. , 2008, The American journal of pathology.
[87] Jia Longfei,et al. PRNP mutations in a series of apparently sporadic neurodegenerative dementias in China , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[88] Shaomin Li,et al. Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory , 2008, Nature Medicine.
[89] N. Ben-Tal,et al. Stress‐protective signalling of prion protein is corrupted by scrapie prions , 2008, The EMBO journal.
[90] T. Bird. Genetic aspects of Alzheimer disease , 2008, Genetics in Medicine.
[91] M. Wozniak,et al. Herpes simplex virus infection causes cellular β-amyloid accumulation and secretase upregulation , 2007, Neuroscience Letters.
[92] J. Trojanowski,et al. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders , 2007, Nature Reviews Neuroscience.
[93] W. Banks,et al. Aluminum complexing enhances amyloid β protein penetration of blood–brain barrier , 2006, Brain Research.
[94] D. Walsh,et al. Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host , 2006, Science.
[95] G. Schellenberg,et al. Early-onset Alzheimer disease in families with late-onset Alzheimer disease: a potential important subtype of familial Alzheimer disease. , 2006, Archives of neurology.
[96] Hilkka Soininen,et al. Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study , 2006, The Lancet Neurology.
[97] Henrik Zetterberg,et al. Alzheimer's disease , 2006, The Lancet.
[98] K. Beyer. α-Synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers , 2006, Acta Neuropathologica.
[99] T. Bliss,et al. Plasticity in the human central nervous system. , 2006, Brain : a journal of neurology.
[100] M. Tsolaki,et al. Relationship between Helicobacter pylori infection and Alzheimer disease , 2006, Neurology.
[101] R. Martins,et al. Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes , 2006, Neurobiology of Aging.
[102] D. Schuppan,et al. Helicobacter pylori upregulates prion protein expression in gastric mucosa: a possible link to prion disease. , 2005, World journal of gastroenterology.
[103] Thomas C. Südhof,et al. α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration , 2005, Cell.
[104] L. Mucke,et al. Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.
[105] T. Wisniewski,et al. An Aggregation-Specific Enzyme-Linked Immunosorbent Assay: Detection of Conformational Differences between Recombinant PrP Protein Dimers and PrPSc Aggregates , 2005, Journal of Virology.
[106] P. Lantos,et al. Overlap between neurodegenerative disorders , 2005, Neuropathology : official journal of the Japanese Society of Neuropathology.
[107] E. M. Jones,et al. Fibril Conformation as the Basis of Species- and Strain-Dependent Seeding Specificity of Mammalian Prion Amyloids , 2005, Cell.
[108] R. Linden,et al. The cellular prion protein modulates phagocytosis and inflammatory response , 2005, Journal of leukocyte biology.
[109] G. Wilcock,et al. Productive herpes simplex virus in brain of elderly normal subjects and Alzheimer's disease patients , 2005, Journal of medical virology.
[110] M. Mattson,et al. Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils , 2005, Science.
[111] I. Grundke‐Iqbal,et al. Tau pathology in Alzheimer disease and other tauopathies. , 2005, Biochimica et biophysica acta.
[112] P. Deyn,et al. Differential diagnosis of 201 possible Creutzfeldt-Jakob disease patients , 2004, Journal of Neurology.
[113] Susan Lindquist,et al. Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein , 2003, Science.
[114] F. Denaro,et al. Coexistence of Alzheimer disease neuropathology with herpes simplex encephalitis. , 2003, Cellular and Molecular Biology.
[115] N. Hooper,et al. ADAMs family members as amyloid precursor protein α‐secretases , 2003 .
[116] J. Regula,et al. Reconstitution of γ-secretase activity , 2003, Nature Cell Biology.
[117] Reinhard Jahn,et al. A Broken α-Helix in Folded α-Synuclein* , 2003, The Journal of Biological Chemistry.
[118] M. V. van Breemen,et al. Amyloid β plaque-associated proteins C1q and SAP enhance the Aβ1–42 peptide-induced cytokine secretion by adult human microglia in vitro , 2003, Acta Neuropathologica.
[119] M. Sy,et al. Cell-surface prion protein interacts with glycosaminoglycans. , 2002, The Biochemical journal.
[120] H. Budka,et al. Mutations of the Prion Protein Gene , 2002, Journal of Neurology.
[121] J. Sodroski,et al. Stimulation of Enveloped Virus Infection by β-Amyloid Fibrils* , 2002, The Journal of Biological Chemistry.
[122] Y. Kitamura,et al. NACP/α-Synuclein, NAC, and β-amyloid pathology of familial Alzheimer's disease with the E184D presenilin-1 mutation: a clinicopathological study of two autopsy cases , 2002, Acta Neuropathologica.
[123] J. Trojanowski,et al. Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[124] G. Wilcock,et al. Herpesviruses in brain and Alzheimer's disease , 2002, The Journal of pathology.
[125] G. Riviere,et al. Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease. , 2002, Oral microbiology and immunology.
[126] K. Arima,et al. Tubulin Seeds α-Synuclein Fibril Formation* , 2002, The Journal of Biological Chemistry.
[127] Seung-Jae Lee,et al. Membrane-bound α-Synuclein Has a High Aggregation Propensity and the Ability to Seed the Aggregation of the Cytosolic Form* , 2002, The Journal of Biological Chemistry.
[128] M. J. Wade,et al. Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease. , 2001, Archives of neurology.
[129] R. Nitsch,et al. Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils , 2001, Science.
[130] B. Steinhoff,et al. Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease , 2001, Journal of neurology, neurosurgery, and psychiatry.
[131] H. Lipp,et al. Learning deficits in mice with persistent Borna disease virus infection of the CNS associated with elevated chemokine expression , 2001, Behavioural Brain Research.
[132] Y. Ono,et al. Phosphorylation of Tau Is Regulated by PKN* , 2001, The Journal of Biological Chemistry.
[133] T. Suzutani,et al. Direct and mononuclear cell mediated effects on interleukin 6 production by glioma cells in infection with herpes simplex virus type 1 , 2001, Journal of medical virology.
[134] L A Beckett,et al. Is the risk of developing Alzheimer's disease greater for women than for men? , 2001, American journal of epidemiology.
[135] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[136] Patrick R. Hof,et al. Tau protein isoforms, phosphorylation and role in neurodegenerative disorders 1 1 These authors contributed equally to this work. , 2000, Brain Research Reviews.
[137] V. Haroutunian,et al. Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. , 2000, Archives of neurology.
[138] A. Roher,et al. Evidence for Seeding of β-Amyloid by Intracerebral Infusion of Alzheimer Brain Extracts in β-Amyloid Precursor Protein-Transgenic Mice , 2000, The Journal of Neuroscience.
[139] B. Hyman,et al. Membrane Association and Protein Conformation of α-Synuclein in Intact Neurons , 2000, The Journal of Biological Chemistry.
[140] B. Dubois,et al. Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. , 1999, American journal of human genetics.
[141] T. Wight,et al. The Sulfate Moieties of Glycosaminoglycans Are Critical for the Enhancement of β‐Amyloid Protein Fibril Formation , 1999, Journal of neurochemistry.
[142] S. Bansil,et al. Correlation between sex hormones and magnetic resonance imaging lesions in multiple sclerosis , 1999, Acta neurologica Scandinavica.
[143] Stanley B. Prusiner,et al. Nobel Lecture: Prions , 1998 .
[144] E. Tschachler,et al. Human keratinocytes express cellular prion-related protein in vitro and during inflammatory skin diseases. , 1998, The American journal of pathology.
[145] E. Corder,et al. Apolipoprotein E and herpes simplex virus 1 in Alzheimer's disease , 1998, The Lancet.
[146] David F. Clayton,et al. The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease , 1998, Trends in Neurosciences.
[147] D. Appelt,et al. Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain , 1998, Medical Microbiology and Immunology.
[148] R B D'Agostino,et al. Lifetime risk of dementia and Alzheimer's disease , 1997, Neurology.
[149] M. L. Schmidt,et al. α-Synuclein in Lewy bodies , 1997, Nature.
[150] Konrad Maurer,et al. Auguste D and Alzheimer's disease , 1997, The Lancet.
[151] M. Billingsley,et al. Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration. , 1997, The Biochemical journal.
[152] J. Kim. Evidence that the precursor protein of non-A beta component of Alzheimer's disease amyloid (NACP) has an extended structure primarily composed of random-coil. , 1997, Molecules and cells.
[153] G. Wilcock,et al. Herpes simplex virus type 1 in brain and risk of Alzheimer's disease , 1997, The Lancet.
[154] Khadija Iqbal,et al. Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[155] P. Lansbury,et al. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. , 1996, Biochemistry.
[156] B. Ghetti,et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[157] J. Trojanowski,et al. Neurofibrillary pathology and aluminum in Alzheimer's disease. , 1995, Histology and histopathology.
[158] David F. Clayton,et al. Characterization of a novel protein regulated during the critical period for song learning in the zebra finch , 1995, Neuron.
[159] B. Chesebro,et al. A 60-kDa Prion Protein (PrP) with Properties of Both the Normal and Scrapie-associated Forms of PrP (*) , 1995, The Journal of Biological Chemistry.
[160] Akihiko Iwai,et al. The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system , 1995, Neuron.
[161] F. Cohen,et al. Prion protein gene variation among primates. , 1995, Journal of molecular biology.
[162] H. Mori,et al. Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. , 1994, Biochemical and biophysical research communications.
[163] J. Trojanowski,et al. Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau , 1994, Neuron.
[164] H. van der Loos,et al. Further ultrastructural evidence that spirochaetes may play a role in the aetiology of Alzheimer's disease. , 1994, Neuroreport.
[165] D. Gajdusek,et al. Spontaneous generation of infectious nucleating amyloids in the transmissible and nontransmissible cerebral amyloidoses , 1994, Molecular Neurobiology.
[166] E. Masliah,et al. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[167] Khadija Iqbal,et al. Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. , 1993, The Journal of biological chemistry.
[168] J. Miklossy,et al. Alzheimer's disease—a spirochetosis? , 1993, Neuroreport.
[169] W. D. Ehmann,et al. Laser microprobe analysis of brain aluminum in Alzheimer' disease , 1993, Annals of neurology.
[170] G. Wilcock,et al. Herpes simplex virus type 1 DNA is present in specific regions of brain from aged people with and without senile dementia of the Alzheimer type , 1992, The Journal of pathology.
[171] W. Müller,et al. Accumulation of transcripts coding for prion protein in human astrocytes during infection with human immunodeficiency virus. , 1992, Biochimica et biophysica acta.
[172] G. Wilcock,et al. Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains , 1991, Journal of medical virology.
[173] J. Trojanowski,et al. A68: a major subunit of paired helical filaments and derivatized forms of normal Tau. , 1991, Science.
[174] W. Dittrich,et al. Learning deficiencies in borna disease virus-infected but clinically healthy rats , 1989, Biological Psychiatry.
[175] R. A. Crowther,et al. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease , 1989, Neuron.
[176] R. Scheller,et al. Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[177] J. Walker,et al. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[178] D. Bal,et al. Perspectives on the etiology of Alzheimer's disease. , 1987, JAMA.
[179] D. McLachlan,et al. Aluminum and alzheimer's disease , 1986, Neurobiology of Aging.
[180] S. Prusiner,et al. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene , 1986, Cell.
[181] S. Mirra,et al. HTLV-III/LAV infection of the central nervous system in a 57-year-old man with progressive dementia of unknown cause. , 1986, The New England journal of medicine.
[182] C. Masters,et al. Amyloid plaque core protein in Alzheimer disease and Down syndrome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[183] H. Wiśniewski,et al. Senile dementia of the Alzheimer type: Possibility of infectious etiology in genetically susceptible individuals , 1984, Acta neurologica Scandinavica. Supplementum.
[184] E. Renvoize,et al. Cytomegalovirus infection and Alzheimer's disease. , 1984, Age and Ageing.
[185] G. Glenner,et al. Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein , 1984 .
[186] A. Salazar,et al. Alzheimer's Disease and Transmissible Virus Dementia (Creutzfeldt‐Jakob Disease) , 1982, Annals of the New York Academy of Sciences.
[187] C. Masters,et al. The familial occurrence of Creutzfeldt-Jakob disease and Alzheimer's disease. , 1981, Brain : a journal of neurology.
[188] M. Petrič,et al. HERPES-SIMPLEX VIRAL GENOME AND SENILE AND PRESENILE DEMENTIAS OF ALZHEIMER AND PICK , 1980, The Lancet.
[189] Ball Mj. Features of Creutzfeldt-Jakob Disease in Brains of Patients with Familial Dementia of Alzheimer Type , 1980, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.
[190] C Peter N Watson. Clinical similarity of Alzheimer and Creutzfeldt‐Jakob disease , 1979, Annals of neurology.
[191] R. Sutton,et al. DETECTION OF HERPES-SIMPLEX VIRAL GENOME IN BRAIN TISSUE , 1979, The Lancet.
[192] S. Rajah,et al. POSSIBLE ASSOCIATION OF ALZHEIMER'S DISEASE WITH HLA-BW15 AND CYTOMEGALOVIRUS INFECTION , 1979, The Lancet.
[193] J. Austin,et al. Precautions in familial transmissible dementia: including familial Alzheimer's disease. , 1978, Archives of neurology.
[194] M. Kirschner,et al. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. , 1977, Journal of molecular biology.
[195] G. Ladurner,et al. IMPROVED LOCALISATION BY SUBTRACTION OF E.M.I. SCANS , 1975, The Lancet.
[196] M. Kirschner,et al. A protein factor essential for microtubule assembly. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[197] G. Keele. COOPERATION BETWEEN SOCIAL WORKERS AND GENERAL PRACTITIONERS , 1975, The Lancet.
[198] E. Lycke,et al. A Serological Study on Mentally Ill Patients , 1974, British Journal of Psychiatry.
[199] M. Thouless,et al. Association between Psychopathic Disorder and Serum Antibody to Herpes Simplex Virus (Type 1) , 1971, British medical journal.
[200] O. Latham,et al. ALZHEIMER'S DISEASE COMPLICATED BY A TERMINAL SALMONELLA INFECTION , 1947, Medical Journal of Australia.
[201] N. Qadi,et al. Genetic Study of Alzheimer's Disease in Saudi Population. , 2019, Journal of Alzheimer's disease : JAD.
[202] M. Pohanka. Oxidative stress in Alzheimer disease as a target for therapy. , 2018, Bratislavske lekarske listy.
[203] T. Murray,et al. Connections Between Herpes Simplex Virus Type 1 and Alzheimer's Disease Pathogenesis. , 2016, Current Alzheimer Research.
[204] F. Mollinedo,et al. Lipid rafts as major platforms for signaling regulation in cancer. , 2015, Advances in biological regulation.
[206] R. Mayeux,et al. Review - Part of the Special Issue: Alzheimer's Disease - Amyloid, Tau and Beyond Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers , 2014 .
[207] W. Deng,et al. Validating GWAS-Identified Risk Loci for Alzheimer’s Disease in Han Chinese Populations , 2014, Molecular Neurobiology.
[208] M. J. BALL,et al. Features of Creutzfeldt-Jakob Disease in Brains of Patients with Familial Dementia of Alzheimer Type , 2014 .
[209] Sudha Seshadri,et al. Genetics of Alzheimer's disease. , 2014, Advances in genetics.
[210] D. Selkoe. Alzheimer's disease. , 2011, Cold Spring Harbor perspectives in biology.
[211] S. Glantz,et al. Cigarette smoking is a risk factor for Alzheimer's Disease: an analysis controlling for tobacco industry affiliation. , 2010, Journal of Alzheimer's disease : JAD.
[212] D. Blacker,et al. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database , 2007, Nature Genetics.
[213] A. Roses. On the discovery of the genetic association of Apolipoprotein E genotypes and common late-onset Alzheimer disease. , 2006, Journal of Alzheimer's disease : JAD.
[214] T. Südhof,et al. Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. , 2005, Cell.
[215] A. Serretti,et al. Genes involved in Alzheimer's disease, a survey of possible candidates. , 2005, Journal of Alzheimer's disease : JAD.
[216] R. Vassar. BACE1: the beta-secretase enzyme in Alzheimer's disease. , 2004, Journal of molecular neuroscience : MN.
[217] N. Hooper,et al. ADAMs family members as amyloid precursor protein alpha-secretases. , 2003, Journal of neuroscience research.
[218] J. Regula,et al. Reconstitution of gamma-secretase activity. , 2003, Nature cell biology.
[219] M. V. van Breemen,et al. Amyloid beta plaque-associated proteins C1q and SAP enhance the Abeta1-42 peptide-induced cytokine secretion by adult human microglia in vitro. , 2003, Acta neuropathologica.
[220] S. Lindquist,et al. Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. , 2003, Science.
[221] J. Sodroski,et al. Stimulation of enveloped virus infection by beta-amyloid fibrils. , 2002, The Journal of biological chemistry.
[222] Y. Kitamura,et al. NACP/alpha-synuclein, NAC, and beta-amyloid pathology of familial Alzheimer's disease with the E184D presenilin-1 mutation: a clinicopathological study of two autopsy cases. , 2002, Acta neuropathologica.
[223] K. Arima,et al. Tubulin seeds alpha-synuclein fibril formation. , 2002, The Journal of biological chemistry.
[224] L. Thal,et al. Characterization of the human alpha-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms. , 2001, Journal of Alzheimer's disease : JAD.
[225] L. Thal,et al. Characterization of the human α-synuclein gene: Genomic structure, transcription start site, promoter region and polymorphisms 1 , 2001 .
[226] R. Mahley,et al. Apolipoprotein E: far more than a lipid transport protein. , 2000, Annual review of genomics and human genetics.
[227] Sheila M. Thomas,et al. Cellular functions regulated by Src family kinases. , 1997, Annual review of cell and developmental biology.
[228] F E Cohen,et al. Prion protein gene variation among primates. , 1997, Journal of molecular biology.
[229] P. Levallois. Aluminum and Alzheimer's disease. , 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
[230] P. Fraser,et al. Aluminium and the pathogenesis of Alzheimer's disease: a summary of evidence. , 1992, Ciba Foundation symposium.
[231] Martin N. Rossor,et al. GENETICS OF ALZHEIMERS-DISEASE , 1990 .
[232] D. Bal,et al. Perspectives on the etiology of Alzheimerʼs disease , 1987 .